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Condition: Diabetes
Therapy: Corticosteroid Therapy

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Total 544 results found since Jan 2013.

Antenatal corticosteroids in specific groups at risk of preterm birth: a systematic review
Conclusions There is a paucity of evidence on ACS for women who have diabetes. ACS therapy may have benefits in women with chorioamnionitis and is probably beneficial in FGR. There is limited direct trial evidence on ACS efficacy in women undergoing planned CS in the late preterm period, though the totality of evidence suggests it is probably beneficial. PROSPERO registration number CRD42021267816.
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Saito, K., Nishimura, E., Ota, E., Namba, F., Swa, T., Ramson, J., Lavin, T., Cao, J., Vogel, J. P. Tags: Open access, Paediatrics Source Type: research

Mucormycosis: update on clinical presentation, diagnosis, and treatment
Curr Opin Infect Dis. 2023 Sep 22. doi: 10.1097/QCO.0000000000000976. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Mucormycosis (MCR) is a common opportunistic mold infection, and Mucorales were recently designated by WHO as priority pathogens. The interest in this infection has risen significantly since the major outbreak of MCR in the context of the COVID-19 pandemic, particularly in India. Herein, we summarize recently (last 24 months) published information regarding clinical aspects of MCR.RECENT FINDINGS: The disease remains protean in its clinical presentation, difficult to diagnose, and challenging to treat. In ...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Natalie J M Dailey Garnes Dimitrios P Kontoyiannis Source Type: research

Identifying clusters of coexisting conditions and outcomes among adults admitted to hospital with community-acquired pneumonia: a multicentre cohort study
We described differences in medications, imaging and outcomes.RESULTS: Patients clustered into 7 subgroups. The low comorbidity subgroup (n = 3052, 27.5%) had no comorbidities. The DM-HF-Pulm subgroup had prevalent diabetes, heart failure and chronic lung disease (n = 1710, 15.4%). One disease category defined each remaining subgroup, as follows: pulmonary (n = 1621, 14.6%), diabetes (n = 1281, 11.6%), heart failure (n = 1370, 12.4%), dementia (n = 1038, 9.4%) and cancer (n = 1013, 9.1%). Corticosteroid use ranged from 11.5% to 64.9% in the dementia and pulmonary subgroups, respectively. Piperacillin-tazobactam use ranged ...
Source: cmaj - September 5, 2023 Category: General Medicine Authors: Sarah L Malecki Hae Young Jung Anne Loffler Mark A Green Samir Gupta Derek MacFadden Nick Daneman Ross Upshur Michael Fralick Lauren Lapointe-Shaw Terence Tang Adina Weinerman Janice L Kwan Jessica J Liu Fahad Razak Amol A Verma Source Type: research

Imaging spectrum, associations and outcomes in acute invasive fungal rhino-ocular-cerebral sinusitis in patients with COVID-19 pneumonia
CONCLUSION: Cross-sectional imaging not only provides the extent of disease spread but also plays a vital role in providing a surgical roadmap to treating surgeons and in predicting prognosis in patients with invasive fungal infections.PMID:37636178 | PMC:PMC10451586 | DOI:10.4103/jfmpc.jfmpc_1189_22
Source: Primary Care - August 28, 2023 Category: Primary Care Authors: Viral B Patel Aashvi Patel Girish Mishra Nilay Shah Mayur K Shinde Raish K Musa Source Type: research

TWiV 1036: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses Florida local transmission of dengue cases reported in Broward and Miami-Dade counties, infants admitted to US intensive care units for RSV infection during the 2022 seasonal peak, long-term risk of death and readmission after hospital admission with COVID-19 among older adults, safety profile and clinical and virological outcomes of Nirmatrelvir-Ritonavir treatment in patients with advanced chronic kidney disease and COVID-19, Fluvoxamine vs placebo for outpatients with symptomatic COVID-19, the effect of corticosteroids, antibiotics, and anticoagulants on the developme...
Source: This Week in Virology - MP3 Edition - August 19, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Diabetes in stiff-person syndrome
Trends Endocrinol Metab. 2023 Aug 14:S1043-2760(23)00148-0. doi: 10.1016/j.tem.2023.07.005. Online ahead of print.ABSTRACTAnti-glutamic acid decarboxylase (GAD) autoantibodies are a hallmark of stiff-person syndrome (SPS) and insulin-dependent diabetes mellitus (IDDM). However, patients with concurrent IDDM and SPS often manifest insulin resistance, and SPS-associated IDDM probably has heterogeneous causes. Some patients manifest IDDM associated only with high titers of anti-GAD65 caused by SPS. By contrast, other patients develop IDDM only after being treated with high-dose corticosteroids or they progress to insulin depe...
Source: Trends in Endocrinology and Metabolism: TEM - August 16, 2023 Category: Endocrinology Authors: Petr Heneberg Source Type: research

A Comparison of the Effects of Dexamethasone and Methylprednisolone, Used on Level-3 Intensive Care COVID-19 Patients, on Mortality: A Multi-Center Retrospective Study
CONCLUSION: Corticosteroids are shown to be beneficial in critical COVID-19, but the role of early corticosteroids in mild COVID-19 patients remains unclear. The anti-inflammatory effects of corticosteroids may have a positive effect by reducing mortality in severe COVID-19 patients. Although dexamethasone was first used for this purpose, methylprednisolone was found to be as effective at standard doses. Methylprednisolone administered at standard doses was associated with greater PaO2/FiO2 ratios than dexamethasone, especially in the severe group requiring MV. High dose pulse steroid doses are closely associated with mort...
Source: J Korean Med Sci - July 25, 2023 Category: General Medicine Authors: Ahmet Sari Osman Ekinci Kemal Tolga Sara çoğlu Recep Bal ık Mesut Aslan Yelda Bal ık Ceren Önal Murat Aslan Semra Cevher Aylin Parmaks ız Şeule Vatansever M ünire Canan Çicek Özge Sayın Ayan Gaye Şensöz Çelik A çelya Toprak Mehmet Y ılmaz Source Type: research