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Total 249 results found since Jan 2013.

Non-invasive monitoring of transplanted endothelial progenitor cells in diabetic ischemic stroke models.
The objectives of this study were to establish a non-invasive imaging strategy to monitor the homing of transplanted EPCs in diabetic stroke mice and to assess the effect of RWJ 67657, an inhibitor of p38 MAPK, on the homing ability of exogenous EPCs. Bone marrow-derived EPCs were labeled in vitro with a multi-functional nanoprobe modified with paramagnetic chelators and fluorophores before being infused into stroke mice. The signal of the nanoprobe reached its peak on day 5 in both magnetic resonance imaging and near-infrared fluorescence imaging after EPC transplantation in wild-type stroke models. The signal enhancemen...
Source: Biomaterials - November 26, 2014 Category: Materials Science Authors: Bai YY, Wang L, Peng XG, Wang YC, Chang D, Zheng S, Ding J, Li C, Ju S Tags: Biomaterials Source Type: research

Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study
ConclusionIschemic stroke subtypes differ between the two phenotypes. Diabetes and male sex have a stronger association with PCiS than ACiS. Definitive MRI-based PCiS diagnosis aids etiological investigation and contributes additional insights into specific risk factors and mechanisms of injury in PCiS.
Source: Journal of Neurology - November 10, 2019 Category: Neurology Source Type: research

Comparison of carotid atherosclerotic plaque characteristics between symptomatic patients with transient ischemic attack and stroke using high-resolution magnetic resonance imaging
CONCLUSIONS: Ischemic stroke patients had larger plaque burden and greater proportion of LRNC in carotid plaques compared to those with TIA. This study suggests that ischemic stroke patients had more vulnerable plaques compared to those with TIA.PMID:35448952 | DOI:10.1186/s12872-022-02624-7
Source: Atherosclerosis - April 22, 2022 Category: Cardiology Authors: Mingming Lu Lichen Zhang Fei Yuan Peng Peng Hongtao Zhang Shitong Liu Yao He Jianming Cai Xihai Zhao Source Type: research

Bilateral medial medullary stroke: A rare stroke syndrome masquerading as myasthenia crisis in a young diabetic lady
J R Coll Physicians Edinb. 2022 Mar;52(1):30-33. doi: 10.1177/14782715221088914.ABSTRACTBilateral medial medullary stroke is a rare stroke syndrome. The clinical presentation of bilateral medial medullary stroke is heterogenous and often overlaps with other non-stroke neurology emergencies such as Guillain-Barrésyndrome, myasthenic crisis and acute vestibular syndrome, leading to misdiagnosis. We wish to present a case of a young lady with type 1 diabetes mellitus, who had presented with subacute neuromuscular weakness which was erroneously treated as myasthenic crisis. Her case was subsequently diagnosed as bilateral med...
Source: Journal of the Royal College of Physicians of Edinburgh - September 23, 2022 Category: General Medicine Authors: Ng Han Sim Benjamin Teo Hock Gin Ong Yoke Ling Elora Wong Kee Yung Kelly Source Type: research

Review of Cardiac Abnormalities with Hypercoagulable Testing in Ischemic Stroke Patients (P4.234)
CONCLUSIONS: We found no relationship between abnormal HT findings and RTLS among individuals with ischemic stroke. However, there may be an association between abnormal HT results and severe LVH that is worthy of further exploration. Previous literature has demonstrated an association between hypertension and hypercoagulability. Disclosure: Dr. Anderson has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Drake has received personal compensation for activities with UCB Pharma as a speaker. Dr. Proytcheva has nothing to disclose. Dr. Coull has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Anderson, N., Shah, A., Drake, K., Proytcheva, M., Coull, B. Tags: Cerebrovascular Disease and Interventional Neurology: Cardiac Source Type: research

Value of Eye Movement Exam in Aiding Precise Localization in Stroke (P1.016)
We present an unusual presentation of midbrain stroke presenting with bilateral ptosis in an African American male with vascular risk factors and concurrent use of bevacizumab. This case illustrates how detailed knowledge of anatomy and detailed neurologic exam remain valuable tools for localizing and diagnosing subtle presentations of common neurologic disease. Case description: A 69 year-old African American man with vascular risk factors including hypertension, hyperlipidemia and poorly controlled diabetes experienced sudden onset horizontal diplopia associated with fatigue. The patient presented to the Emergency Depart...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Khandker, N., Schmerler, D., Mahajan, S., Serra, A., Strbian, D. Tags: Cerebrovascular Disease and Interventional Neurology I ePosters Source Type: research

Brain Infarction MRI Pattern in Stroke Patients with Intracardiac Thrombus
Conclusions: ICT-related stroke is associated with acute SCCI presence on MRI.Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT04456309.Cerebrovasc Dis
Source: Cerebrovascular Diseases - June 17, 2021 Category: Neurology Source Type: research

Trimethylamine N-Oxide and White Matter Hyperintensity Volume Among Patients With Acute Ischemic Stroke
CONCLUSIONS AND RELEVANCE: In this observational study, TMAO was associated with cerebral small vessel disease determined by WMHV and acute lacunar infarction. The association was independent of traditional vascular risk factors.PMID:37610752 | DOI:10.1001/jamanetworkopen.2023.30446
Source: Atherosclerosis - August 23, 2023 Category: Cardiology Authors: Naruchorn Kijpaisalratana Zsuzsanna Ament Matthew B Bevers Varun M Bhave Ana-Lucia Garcia Guarniz Catharine A Couch M Ryan Irvin W Taylor Kimberly Source Type: research