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Specialty: Neurology
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Total 1259 results found since Jan 2013.

The reasons for not returning to work and health-related quality of life among young and middle-aged patients with stroke: A cross-sectional study
ConclusionsMore than half did not RTW within 1 year in our study. The results will help inform future research to identify interventions to promote RTW and improve HRQoL for young and middle-aged patients with stroke.
Source: Frontiers in Neurology - February 23, 2023 Category: Neurology Source Type: research

Risk factor identification and prediction models for prolonged length of stay in hospital after acute ischemic stroke using artificial neural networks
ConclusionThe artificial neural network model achieved adequate discriminative power for predicting prolonged length of stay after acute ischemic stroke and identified crucial factors associated with a prolonged hospital stay. The proposed model can assist in clinically assessing the risk of prolonged hospitalization, informing decision-making, and developing individualized medical care plans for patients with acute ischemic stroke.
Source: Frontiers in Neurology - February 9, 2023 Category: Neurology Source Type: research

The association between HDL ‐C and stroke in the middle‐aged and elderly: A cross‐sectional study
ConclusionWe found a nonlinear relationship between HDL-C and total stroke. Our study reveals a range of inverse associations between HDL-C and stroke (HDL-C<1.55  mmol/L), especially among men and Whites. This finding suggested that maintaining an appropriate HDL-C range may be beneficial in reducing the incidence of stroke.
Source: Brain and Behavior - February 7, 2023 Category: Neurology Authors: Yang Hu, Min Song, Dongmei Wu, Yuqing Zhang, Gongbo Li, Haiyan Luo Tags: ORIGINAL ARTICLE Source Type: research

Sex differences and risk factors in recurrent ischemic stroke
ConclusionHypertension and dyslipidemia were significant risk factors of recurrent ischemic stroke in both genders. Smoking and alcohol drinking were significant risk factors associated with ischemic stroke recurrence in males. Therefore, smoking cessation and alcohol abstinence are recommended after the first stroke to prevent recurrent ischemic stroke especially for males. Diabetes was a significant risk factor of ischemic stroke recurrence in females. More extensive studies are needed to understand the causal relationship of each factors with ischemic stroke recurrence according to sex differences and specification of p...
Source: Frontiers in Neurology - January 26, 2023 Category: Neurology Source Type: research

Role of plaque inflammation in symptomatic carotid stenosis
ConclusionPlaque inflammation as quantified on FDG-PET may serve as a reliable biomarker for risk stratification among patients with ECAD and recent TIA or ischemic stroke. Future studies should evaluate whether patients with significant plaque inflammation as quantified on FDG-PET benefit from carotid revascularization and/or anti-inflammatory therapy.
Source: Frontiers in Neurology - January 24, 2023 Category: Neurology Source Type: research

Blood pressure and Alzheimer's disease: A review of meta-analysis
ConclusionSBP is associated with both cerebrovascular disease and AD. Therefore, future studies should use other uncontrolled factors, such as cardiovascular diseases, diabetes, and stroke, to explain the relationship between SBP and AD.
Source: Frontiers in Neurology - January 11, 2023 Category: Neurology Source Type: research

Metformin enhances neural precursor cells migration and functional recovery after ischemic stroke in mice
Exp Brain Res. 2023 Jan 8. doi: 10.1007/s00221-023-06547-3. Online ahead of print.ABSTRACTResident neural precursor cells (NPCs) activation is a promising therapeutic strategy for brain repair. This strategy involves stimulating multiple stages of NPCs development, including proliferation, self-renewal, migration, and differentiation. Metformin, an FDA-approved diabetes drug, has been shown to promote the proliferation and differentiation of NPCs. However, it is still unclear whether metformin promotes the migration of NPCs. EVOS living cell imaging system was used for observing the migration for primary NPCs dynamically i...
Source: Brain Research - January 7, 2023 Category: Neurology Authors: Liang Zhang Jing Zhang Xiaoming Zhu Wei Jiao Yang Yang Youping Wu Likun Yang Yuhai Wang Source Type: research

Prognostic Value of Stress Hyperglycaemia Ratio in Young Patients with Ischaemic Stroke or Transient Ischaemic Attack
Conclusion: The SHR is independently related to more severe stroke and an increased risk of poor functional outcomes among young adults with ischaemic stroke or TIA.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 4, 2023 Category: Neurology Source Type: research

Dizziness in a tertiary neurological department: A cross ‐sectional study
ConclusionThe diagnosis and management of dizziness remain a challenge for clinicians. Vertigo and light-headedness were the most common symptoms among different types of dizziness. Benign paroxysmal positional vertigo and stroke/transient ischemic attack were among the leading causes for common dizziness disorders. The prognosis of most dizzy patients was good.
Source: Brain and Behavior - December 30, 2022 Category: Neurology Authors: Youjin Shen, Wentao Liu, Xiaokun Qi Tags: ORIGINAL ARTICLE Source Type: research

Fluoxetine or Venlafaxine for Early Post Stroke Depression
Conclusions: PSD in the early phase affects a substantial number of the stroke patients. Venlafaxine has got a better outcome and adverse event profile compared to fluoxetine in this group of patients. However, larger multicenter studies will provide more helpful data in this area.
Source: Neurology India - December 19, 2022 Category: Neurology Authors: Vivek K Nambiar J Parvathy Tania M Philip K Abhijith S Sreeni Naveen K Panicker Amrutha V Ajai TS Dhanya Source Type: research

Global Cortical Atrophy Is Associated with an Unfavorable Outcome in Stroke Patients on Oral Anticoagulation
Conclusion: GCA was associated with our composite outcome also after adjusting for other cSVD markers (i.e., CMB, WMH) and age, indicating that GCA may potentially serve as a prognostic marker for stroke patients with atrial fibrillation on oral anticoagulation.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 13, 2022 Category: Neurology Source Type: research

Factors associated with cognitive impairment at 3, 6, and 12 months after the first stroke among Lebanese survivors
ConclusionThe risk of PSCI among Lebanese stroke survivors was high especially in the acute phase, depending on various determinants. Health care providers are invited to implement an emergency rehabilitation program for an appropriate successful management of the risk factors in order to reduce stroke burden and to improve overall cognitive performance.
Source: Brain and Behavior - December 10, 2022 Category: Neurology Authors: Celina F. Boutros, Walaa Khazaal, Maram Taliani, Najwane Said Sadier, Pascale Salameh, Hassan Hosseini Tags: ORIGINAL ARTICLE Source Type: research

White matter hyperintensities are an independent predictor of cognitive decline 3 years following first-ever stroke —results from the PROSCIS-B study
ConclusionHigher WMH burden was associated with a significant decline in cognition 3 years post-stroke in this cohort of first-ever stroke patients.
Source: Journal of Neurology - December 6, 2022 Category: Neurology Source Type: research

Genetic loci, rs17817449 and rs6567160, known for obesity and the risk of stroke events among middle-aged and older Chinese people
ConclusionThe G allele of rs17817449 at the FTO, not rs6567160 at the MC4R, was associated with a decreased risk of fatal stroke occurrence; its functional role in stroke should be explored in relatively healthy middle-aged to older Chinese people.
Source: Frontiers in Neurology - December 2, 2022 Category: Neurology Source Type: research