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Condition: Diabetes
Drug: Estradiol
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Total 213 results found since Jan 2013.
Factors Associated With Circulating Sex Hormones in Men : Individual Participant Data Meta-analyses
CONCLUSION: Multiple factors are associated with variation in male testosterone, SHBG, and LH concentrations. Reduced testosterone and increased LH concentrations may indicate impaired testicular function after age 70 years. Interpretation of individual testosterone measurements should account particularly for age older than 70 years, obesity, diabetes, and cancer.PRIMARY FUNDING SOURCE: Medical Research Future Fund, Government of Western Australia, and Lawley Pharmaceuticals. (PROSPERO: CRD42019139668).PMID:37639720 | DOI:10.7326/M23-0342
Source: Annals of Internal Medicine - August 28, 2023 Category: Internal Medicine Authors: Ross J Marriott Kevin Murray Robert J Adams Leen Antonio Christie M Ballantyne Douglas C Bauer Shalender Bhasin Mary L Biggs Peggy M Cawthon David J Couper Adrian S Dobs Leon Flicker David J Handelsman Graeme J Hankey Anke Hannemann Robin Haring Benjumin Source Type: research
Accelerated bone loss in older men with severe abdominal aortic calcification - the prospective MINOS study
CONCLUSIONS: Severe AAC is associated with faster bone loss in older men and may contribute to the higher fracture risk observed in this population.PMID:37610245 | DOI:10.1210/clinem/dgad459
Source: The Journal of Clinical Endocrinology and Metabolism - August 23, 2023 Category: Endocrinology Authors: Pawel Szulc Joshua R Lewis Roland Chapurlat Source Type: research
The impact of non-caloric artificial sweetener aspartame on female reproductive system in mice model
CONCLUSION: Non-nutritive artificial sweeteners including aspartame negatively impact the function of ovaries and feedback mechanism of reproductive hormones by affecting the hypothalamic-pituitary-gonadal axis. In light of present findings the aspartame negatively impacted the reproductive system of female mice. More studies are required to identify the molecular mechanism and the pathways involved.PMID:37580716 | DOI:10.1186/s12958-023-01115-4
Source: Reproductive Biology - August 14, 2023 Category: Reproduction Medicine Authors: Ab Qayoom Naik Tabassum Zafar Vinoy K Shrivastava Source Type: research
The relation between vitamin D and the adolescents' mid-luteal estradiol and progesterone
CONCLUSIONS: The mid-luteal E2 and P statistically decreased after vit. D intake (50,000 IU of vit. D weekly for 2 months). Significant negative correlations between the 25(OH)D, and both the mid-luteal E2 and P were detected in this study. The relation between vit. D and ovarian steroids, and the effect of vit. D intake on ovarian steroids need further larger studies.PMID:37522690 | DOI:10.26355/eurrev_202307_33150
Source: Pharmacological Reviews - July 31, 2023 Category: Drugs & Pharmacology Authors: A Donayeva A Amanzholkyzy I A Abdelazim S Saparbayev R Nurgaliyeva A Kaldybayeva A Zhexenova E Stankevicius Z Khamidullina G Gubasheva D Ayaganov I I Samaha Source Type: research
Greb1 Transiently Accelerates Pancreatic β-Cell Proliferation in Diabetic Mice Exposed to Estradiol
Am J Pathol. 2023 Aug;193(8):1081-1100. doi: 10.1016/j.ajpath.2023.04.012.ABSTRACTDecrease of pancreatic β cells leads to diabetes. In an inducible cAMP early suppressor (ICER-Iγ) transgenic mouse model of severe type 2 diabetes with reduced insulin production and depleted β cells, supplementation with high concentrations of 17β-estradiol (E2) markedly enhances β-cell proliferation and normalizes glucose levels. The current study explored the underlying mechanisms leading to a dynamic increase of β cells and pathologic changes in diabetic mice exposed to E2. Gene expression profiling of pancreatic islets of 6-month-o...
Source: The American Journal of Pathology - July 29, 2023 Category: Pathology Authors: Akari Inada Yohichi Yasunami Atsushi Yoshiki Yo-Ichi Nabeshima Oogi Inada Source Type: research
Impact of 17 β-Estradiol on vascular function in ovariectomized rats with diabetes mellitus
Asian J Surg. 2023 Jul 18:S1015-9584(23)01056-4. doi: 10.1016/j.asjsur.2023.07.062. Online ahead of print.NO ABSTRACTPMID:37474384 | DOI:10.1016/j.asjsur.2023.07.062
Source: Asian Journal of Surgery - July 20, 2023 Category: Surgery Authors: Ye Yuan Rui Liu Rifang Gu Xuqiang Nie Source Type: research
