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Johnson & Johnson Single-Shot COVID-19 Vaccine Phase 3 Data Published in New England Journal of Medicine
NEW BRUNSWICK, N.J., April 21, 2021 – Johnson & Johnson (the Company) today announced publication in the New England Journal of Medicine of primary data from the Phase 3 ENSEMBLE clinical trial for its single-dose COVID-19 vaccine, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen). The publication of the primary analysis follows the topline efficacy and safety data announced in January, showing the trial met all primary and key secondary endpoints, and found that the Johnson & Johnson single-dose COVID-19 vaccine prevented hospitalization and death across all study participants ...
Source: Johnson and Johnson - April 21, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Academies Call for Global Action to Reduce Air Pollution
The U.S. National Academy of Sciences and U.S. National Academy of Medicine joined the science academies of South Africa, Brazil, and Germany today in issuing a statement calling for urgent worldwide action to reduce air pollution. The statement was handed over to senior United Nations representatives and diplomats from the four nations at a ceremony today in New York. Air pollution is a cross-cutting aspect of many UN Sustainable Development Goals. Air pollution is estimated to contribute to the premature deaths of at least 5 million people worldwide per year, as well as to chronic health conditions such as heart disease,...
Source: News from the National Academies - June 19, 2019 Category: Science Source Type: news

Editorial: Shaping of Human Immune System and Metabolic Processes by Viruses and Microorganisms
Conclusions In conclusion, articles in this Research Topic made a very significant contribution to our understanding of the role played by environmental factors, dysbiotic conditions, and infections in triggering diseases. Since this is a rapidly expanding area of research, many other factors contributing to the onset of these diseases are not covered here. We are confident, however, that further studies will expand the list as well as bring a better understanding of mechanisms involved in the onset of autoimmune and autoinflammatory diseases. Author Contributions All authors listed have made a substantial, direct and i...
Source: Frontiers in Microbiology - April 16, 2019 Category: Microbiology Source Type: research

Drought in the Semiarid Region of Brazil: Exposure, Vulnerabilities and Health Impacts from the Perspectives of Local Actors
Conclusion The results obtained from this research shows, in general, the fragility in the social and political infrastructure necessary to improve the living conditions of populations, particularly those that depend on family agriculture in drought prone areas. The conditions of social, economic and environmental vulnerabilities presented in the region can be amplified by the drought process, and can aggravate the impacts resulting drought events, thus disadvantaging the population of this region, as shown in the Fig. 1. The general perception of the interviewees of the health sector shows an agreement with what is found...
Source: PLOS Currents Disasters - October 29, 2018 Category: International Medicine & Public Health Authors: Aderita Sena Source Type: research

Clinical and Laboratory Profile of Zika and Dengue Infected Patients: Lessons Learned From the Co-circulation of Dengue, Zika and Chikungunya in Brazil
In conclusion, our data characterized the occurrence of an ongoing triple epidemic caused by DENV, ZIKV and CHIKV in Campo Grande, MS, Brazil. Importantly, the knowledge about dengue or zika severity in co-infected individuals is still unknown, however we provided here, new contributions related to the clinical presentations and laboratorial parameters during DENV and ZIKV infections, in an endemic scenario. Author Contributions Performed the experiments: ELA, TMALS, RVC, FBS. Contribute reagents material analyses tools: ELA, FBS, RVC. Wrote the paper: ELA. RVC. Participate in patient enrollment and records: ELA, RVC, TMA...
Source: PLOS Currents Outbreaks - February 15, 2018 Category: Epidemiology Authors: Elzinandes Leal de Azeredo Source Type: research