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CCR5- Δ32 polymorphism: a possible protective factor for post-stroke depressive symptoms
CONCLUSION: Carriers of the CCR5-Δ32 allele had a lower tendency to develop depressive symptoms post-stroke, and this phenomenon was more prominent in women. These findings could have clinical implications; they suggest a mechanism-based treatment target for post-stroke depression. Drugs mimicking this loss-of-function mutation exist and could serve as a novel antidepressant therapy.PMID:34291627 | DOI:10.1503/jpn.200197
Source: Journal of Psychiatry and Neuroscience - July 22, 2021 Category: Psychiatry Authors: Oren Tene Hen Hallevi Jeremy Molad Saly Usher Estelle Seyman Natan M Bornstein Shani Shenhar-Tsarfaty Einor Ben Assayag Source Type: research

IJERPH, Vol. 18, Pages 13001: Stroke Survivors & rsquo; Personal Efficacy Beliefs and Outcome Expectations of Tai Chi Exercise: A Qualitative Descriptive Study
IJERPH, Vol. 18, Pages 13001: Stroke Survivors’ Personal Efficacy Beliefs and Outcome Expectations of Tai Chi Exercise: A Qualitative Descriptive Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph182413001 Authors: Ruth Taylor-Piliae Hanne Dolan Aodet Yako Prior qualitative research conducted among stroke survivors to explore the potential benefits and challenges of participating in tai chi exercise during stroke recovery is limited to those without depression. A qualitative descriptive approach was used. Social Cognitive Theory and Complex Systems Biology prov...
Source: International Journal of Environmental Research and Public Health - December 9, 2021 Category: Environmental Health Authors: Ruth Taylor-Piliae Hanne Dolan Aodet Yako Tags: Article Source Type: research

The effects of racism and resilience on Black stroke- survivor quality of life: Study protocol and rationale for a mixed-methods approach
This study aims to examine the effects of experiences of racism and resilience on Black SS QoL during early stroke recovery. This article presents the study protocol.Methods and analysesThis will be a prospective observational mixed-methods study. Black community-dwelling adults who are within 4 weeks of a stroke will be eligible for inclusion. Baseline measures will include the exposure variables of experiences of racism and resilience. Covariates measured at baseline include sociodemographic variables (age, sex, marital status, education, income, health insurance, employment status, number of people in household, residen...
Source: Frontiers in Neurology - August 10, 2022 Category: Neurology Source Type: research

Cognitive impairment and hypothymia in post stroke patients
Abstract: 129 patients aged 18–84 in early rehabilitation period of the first hemispheric ischemic stroke and 48 patients with cerebrovascular disorders without stroke in anamnesis were observed. Cognitive functions (MMSE, FAB, Clock Drawing Test, the 5-Word test, attention assessment, Semantic Verbal Fluency test) and emotional sphere (CES-D) were studied. Investigation was carried out twice during the early recovery period 3–4weeks and 3months after the stroke. Statistically significant decrease of cognitive functions in comparison with control group data was revealed. Cognitive deficiency and depressed mood were fix...
Source: Journal of the Neurological Sciences - December 11, 2012 Category: Neurology Authors: L. Pustokhanova, E. Morozova Tags: Original Articles Source Type: research

Effectiveness of interventions for adults with psychological or emotional impairment after stroke: an evidence-based review.
Abstract This evidence-based review was conducted to evaluate the effectiveness of occupational therapy interventions to prevent or mitigate the effects of psychological or emotional impairments after stroke. Thirty-nine journal articles met the inclusion criteria. Six types of interventions were identified that addressed depression, anxiety, or mental health-related quality of life: exercise or movement based, behavioral therapy and stroke education, behavioral therapy only, stroke education only, care support and coordination, and community-based interventions that included occupational therapy. Evidence from we...
Source: The American Journal of Occupational Therapy - January 1, 2015 Category: Occupational Health Authors: Hildebrand MW Tags: Am J Occup Ther Source Type: research

Family Functioning and Depression in Primary Caregivers of Stroke Patients in China
Conclusion Assessment of family functioning may help determine which caregivers are most at risk for developing depressive syndrome.
Source: International Journal of Nursing Sciences - May 12, 2015 Category: Nursing Source Type: research

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