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Condition: Obesity
Nutrition: Weight Loss

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Total 226 results found since Jan 2013.

Just a few extra pounds increases heart failure risk
Conclusion This large study uses an interesting genetic approach (Mendelian randomisation) to suggest obesity increases the risk of heart failure and adverse changes in liver enzymes. The combination of a very large sample, prospectively collected information, and a wide range of cardiometabolic measures lend credibility to the findings. The method the researchers used is also thought to reduce the chances of factors other than BMI influencing results, and the chance that the ‘outcome’ could be causing the ‘exposure’ (reverse causality). The main limitation of this kind of research is that assumptions need to be m...
Source: NHS News Feed - June 26, 2013 Category: Consumer Health News Tags: Obesity Lifestyle/exercise Source Type: news

If you could propose one idea to help improve health care delivery in the United States, what would it be?
Thumbnail: Tags: conversationsphrma conversationslarry hausnermyrl weinbergchris hansennancy brownContributors: 11621161115911631173Contributions: Read Larry Hausner's bio Despite the rapid development of innovative technologies in the health care field, we have yet to discover a panacea that will easily transform our health care system into one that provides high-quality and cost-effective care.  What we have discovered and come to agree on over the last decade is that our sick care system must be reconfigured to a health care system that emphasizes wellness and prevention.  For that reason, I offer ...
Source: PHRMA - June 24, 2013 Category: Pharmaceuticals Authors: rlowe Source Type: news

Diabetes drugs may be linked to pancreatic cancer
Conclusion This article presents important concerns that glucagon-like peptide-1 (GLP-1) agonists and dipeptidylpeptidase-4 (DPP-4) inhibitors could potentially increase the risk of inflammation and cancerous changes in the pancreas. The agencies that regulate medicines in Europe and the USA are aware of these issues, and told the BMJ that their analyses show increased reporting of pancreatic cancer among people taking these types of drugs. However, the agencies note that it has not been established whether these drugs directly cause the adverse effects seen in the pancreas. Both agencies are reviewing emerging eviden...
Source: NHS News Feed - June 10, 2013 Category: Consumer Health News Tags: Medication Diabetes QA articles Source Type: news

Should visceral fat be reduced to increase longevity?
Abstract Several epidemiologic studies have implicated visceral fat as a major risk factor for insulin resistance, type 2 diabetes mellitus, cardiovascular disease, stroke, metabolic syndrome and death. Utilizing novel models of visceral obesity, numerous studies have demonstrated that the relationship between visceral fat and longevity is causal while the accrual of subcutaneous fat does not appear to play an important role in the etiology of disease risk. Specific recommended intake levels vary based on a number of factors, including current weight, activity levels, and weight loss goals. It is discussed the nee...
Source: Ageing Research Reviews - June 10, 2013 Category: Genetics & Stem Cells Authors: Finelli C, Sommella L, Gioia S, La Sala N, Tarantino G Tags: Ageing Res Rev Source Type: research

Randomized controlled pilot study of a SystemCHANGETM weight management intervention in stroke survivors: rationale and protocol
This study will be the first randomized controlled trial to evaluate the efficacy and safety of a weight management intervention in stroke survivors using the SystemCHANGETM approach. Furthermore, it will be the first empirically-examined comprehensive lifestyle intervention designed to target physical activity, nutrition, and sleep to promote weight loss in stroke survivors.Trial registration: ClinicalTrials.gov Identifier: NCT01776034
Source: Trials - May 7, 2013 Category: Journals (General) Authors: Matthew PlowShirley MooreJohn KirwanFredrick FrostIrene KatzanSue JaegerJay Alberts Source Type: research

Risk Factors For Heart Disease Likely Decrease Brain Function Too
Brain function in adults as young as 35 may decline as their heart disease risk factors increase, according to new research in the American Heart Association journal Stroke. "Young adults may think the consequences of smoking or being overweight are years down the road, but they aren't," said Hanneke Joosten, M.D., lead author and nephrology fellow at the University Medical Center in Groningen, The Netherlands. "Most people know the negative effects of heart risk factors such as heart attack, stroke and renal impairment, but they do not realize it affects cognitive health...
Source: Health News from Medical News Today - May 6, 2013 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news

Hard times in Cuba linked to better national health
Conclusion This is an interesting study that appears to show that modest weight loss within a relatively short period across the whole population is associated with a downward trend in diabetes and reductions in death rates from both diabetes and heart disease. Similarly, weight regain was associated with an increase in diabetes incidence, prevalence and mortality as well as a slowing down in the decline of cardiovascular deaths. This type of study draws on many different data sources and, as such, there is a possibility of error. Also, as the authors point out, data was missing on diabetes incidence during the crisis year...
Source: NHS News Feed - April 10, 2013 Category: Consumer Health News Tags: Food/diet Heart/lungs Diabetes Source Type: news

Pharmacotherapy of obesity: clinical treatments and considerations.
Abstract Obesity is a world-wide epidemic associated with significant morbidity and mortality which costs billions of dollars per year. The associated related conditions are many and include heart disease, stroke, type II diabetes mellitus, sleep apnea and certain types of cancer. Given that it is a multifactorial problem, the treatments must also address the numerous causes associated with the development of obesity. The neurohormonal regulation of feeding and energy is a complex system often necessitating modification through more than 1 pathway to achieve weight loss. Therefore, in addition to lifestyle changes...
Source: The American Journal of the Medical Sciences - April 1, 2013 Category: Journals (General) Authors: Holes-Lewis KA, Malcolm R, O'Neil PM Tags: Am J Med Sci Source Type: research

Young Women Witth High BMI At Increased Risk For Heart Attack, Stroke
A nationwide study of women in Denmark who are of child-bearing age finds that those who are obese appear to have a much greater risk of heart attack or stroke, according to research presented at the American College of Cardiology's 62nd Annual Scientific Session. In fact, women with a high body mass index (BMI) - a measure of the body's fat content - that is indicative of obesity were twice as likely as those of normal weight to suffer a potentially life-threatening heart attack or stroke within just four to five years following childbirth...
Source: Health News from Medical News Today - March 11, 2013 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news

Overweight and obese middle-aged women have increased risk of venous thromboembolism, particularly following surgery
Commentary on Parkin L, Sweetland S, Balkwill A, et al.. for the Million Women Study Collaborators. Body mass index, surgery and risk of venous thromboembolism in middle-aged women: a cohort study. Circulation 2012;125:1897–904. Implications for practice and research Obesity is associated with an increased risk of venous thromboembolism (VTE) including both spontaneous and postoperative events. Further research is needed regarding factors responsible for the increase in postoperative VTE in overweight patients, and whether management should be altered (eg, increased focus on postoperative mobilisation, altered doses ...
Source: Evidence-Based Nursing - March 8, 2013 Category: Nursing Authors: McRae, S. Tags: Drugs: cardiovascular system, Stroke, Hypertension, Obesity (nutrition), Venous thromboembolism, Health education, Obesity (public health), Screening (public health), Smoking, Tobacco use Women ' s health Source Type: research

Orlistat reduces weight but its cost-effectiveness remains unclear
This study aimed to evaluate the effectiveness and cost effectiveness of three pharmacological interventions (orlistat, sibutramine and rimonabant) in obese patients in...
Source: Evidence-Based Nursing - March 8, 2013 Category: Nursing Authors: Veerman, L. Tags: Health policy, General practice / family medicine, Drugs: cardiovascular system, Stroke, Obesity (nutrition), Health service research, Health education, Obesity (public health) Primary healthcare Source Type: research

Acute Stroke in Young Women Taking Phentermine (P01.249)
CONCLUSIONS: We present here two patients with mild underlying cerebrovascular risk factors who presented with acute stroke after taking diet pills containing phentermine. The public should be aware of the possible association between stroke and phentermine. More long-term outcomes research is necessary to understand the safety of phentermine-containing diet pills. Patients with cerebrovascular risk factors should be cautious about using Phentermine containing diet pills.Disclosure: Dr. Smit has nothing to disclose. Dr. Cutting has received personal compensation for activities with F1000. Dr. Conners has nothing to disclos...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Smit, L., Cutting, S., Conners, J., Lee, V., Song, S. Tags: P01 Cerebrovascular Disease I Source Type: research

Review of the key results from the Swedish Obese Subjects (SOS) trial – a prospective controlled intervention study of bariatric surgery
Abstract Obesity is a risk factor for diabetes, cardiovascular disease events, cancer and overall mortality. Weight loss may protect against these conditions, but robust evidence for this has been lacking. The Swedish Obese Subjects (SOS) study is the first long‐term, prospective, controlled trial to provide information on the effects of bariatric surgery on the incidence of these objective endpoints. The SOS study involved 2010 obese subjects who underwent bariatric surgery [gastric bypass (13%), banding (19%) and vertical banded gastroplasty (68%)] and 2037 contemporaneously matched obese control subjects receiving usu...
Source: Journal of Internal Medicine - February 8, 2013 Category: Internal Medicine Authors: L. Sjöström Tags: Review Source Type: research

Link Between TV Viewing, Sedentary Lifestyle In Teens And Disease Risk In Adulthood
A team of scientists at Umea University, in collaboration with colleagues in Melbourne, Australia, have found that television viewing and lack of exercise at age 16 is associated with the risk of developing metabolic syndrome at 43 years age. Metabolic syndrome is a name for the disorder of metabolism - a combination of abdominal obesity, elevated blood lipids, hypertension and impaired glucose tolerance - which provides for a significantly increased risk of developing type 2 diabetes, stroke and cardiovascular disease...
Source: Health News from Medical News Today - February 3, 2013 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news

Any defence of sugar is pure confection | Aseem Malhotra
More and more people are challenging the food industry's PR machine. The evidence shows that sugar, not fat, is the enemyThe public health minister, Anna Soubry, has commented that the poor are more likely to be obese. It is well known that social status is linked to health, but her comments were also motivated by a mentality that victimises the most vulnerable. She should really be directing her criticism at the food industry. There is no doubt that an oversupply of cheap junk food fuelled by unregulated and irresponsible marketing limits our ability to make healthy choices. But there is an equally important question that...
Source: Guardian Unlimited Science - January 24, 2013 Category: Science Authors: Aseem Malhotra Tags: Comment Food & drink industry Obesity Health guardian.co.uk Health policy Society UK news Life and style Business Science Comment is free Source Type: news