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Condition: Obesity
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Total 2966 results found since Jan 2013.

Association between the rs2241883 polymorphism of the fatty acid ‐binding protein‐1 (FABP1) gene and obesity in a population of MASHAD study cohort
ConclusionThe results showed that CC genotype for rs2241883 polymorphism is related to an increased risk of the obesity in dominant and codominant models in a population of MASHAD study cohort.
Source: Molecular Genetics & Genomic Medicine - April 8, 2023 Category: Genetics & Stem Cells Authors: Mohsen Valizadeh, Malihe Aghasizadeh, Fatemeh Shaghi, Ali Moradi, Haleh S. T. Afshari, Reza Zare ‐Feyzabadi, Maryam Saberi‐Karimian, Mohammad Hashemi, Fatemeh N. S. Doust, Mohsen Nematy, Ensieh A. Bahre, Seyed H. Aghaei‐Bakhtiari, Hamide Tags: ORIGINAL ARTICLE Source Type: research

Association between the rs2241883 polymorphism of the fatty acid-binding protein-1 (FABP1) gene and obesity in a population of MASHAD study cohort
CONCLUSION: The results showed that CC genotype for rs2241883 polymorphism is related to an increased risk of the obesity in dominant and codominant models in a population of MASHAD study cohort.PMID:37026586 | DOI:10.1002/mgg3.2173
Source: Atherosclerosis - April 7, 2023 Category: Cardiology Authors: Mohsen Valizadeh Malihe Aghasizadeh Fatemeh Shaghi Ali Moradi Haleh S T Afshari Reza Zare-Feyzabadi Maryam Saberi-Karimian Mohammad Hashemi Fatemeh N S Doust Mohsen Nematy Ensieh A Bahre Seyed H Aghaei-Bakhtiari Hamideh Ghazizadeh Hamideh Safarian-Bana Ni Source Type: research

Participation by patients from low- and middle-income countries (LMICs) in trial evidence supporting secondary stroke prevention guideline recommendations
CONCLUSIONS: Compared to their global burden of stroke, LMICs are underrepresented in key clinical trials used in formulating a prominent global stroke prevention guideline. While current therapeutic recommendations are likely applicable to practice settings throughout the world, greater involvement of patients from LMIC settings will enhance the contextual relevance and generalizability of recommendations to these disparate populations.PMID:37028264 | DOI:10.1016/j.jns.2023.120641
Source: Atherosclerosis - April 7, 2023 Category: Cardiology Authors: Priscilla Abrafi Opare-Addo Fred Stephen Sarfo Patrick Opoku Berchie Minas Aikins Bruce Ovbiagele Source Type: research

Association between the rs2241883 polymorphism of the fatty acid-binding protein-1 (FABP1) gene and obesity in a population of MASHAD study cohort
CONCLUSION: The results showed that CC genotype for rs2241883 polymorphism is related to an increased risk of the obesity in dominant and codominant models in a population of MASHAD study cohort.PMID:37026586 | DOI:10.1002/mgg3.2173
Source: Atherosclerosis - April 7, 2023 Category: Cardiology Authors: Mohsen Valizadeh Malihe Aghasizadeh Fatemeh Shaghi Ali Moradi Haleh S T Afshari Reza Zare-Feyzabadi Maryam Saberi-Karimian Mohammad Hashemi Fatemeh N S Doust Mohsen Nematy Ensieh A Bahre Seyed H Aghaei-Bakhtiari Hamideh Ghazizadeh Hamideh Safarian-Bana Ni Source Type: research

Preventing Adverse Cardiovascular Outcomes in Pregnancy Complicated by Obesity
AbstractPurpose of ReviewObesity is a chronic disease that is becoming increasingly prevalent, and more individuals of reproductive age have obesity prior to becoming pregnant. Obesity in pregnancy is associated with short- and long-term adverse consequences for both the birthing person and their offspring which have been associated with increased long-term cardiovascular morbidity and mortality. The goal of this review is to discuss what is currently understood about the relationship between maternal obesity and adverse pregnancy outcomes (APOs), the association between APOs and future cardiovascular disease (CVD) risk, a...
Source: Current Obstetrics and Gynecology Reports - April 6, 2023 Category: OBGYN Source Type: research

Clinical characteristics, etiological profile, treatment and long term outcomes in patients with non ischemic systolic heart failure; Himachal Pradesh heart failure registry (HP-HF registry)
CONCLUSIONS: Patients of NISHF were middle-aged population with severely depressed LV systolic function with significant incident morbidity and mortality. Early detection of risk factors and their risk management and enhancing the use of guideline directed treatment may improve the outcomes.PMID:37003535 | DOI:10.1016/j.ihj.2023.03.007
Source: Indian Heart J - April 1, 2023 Category: Cardiology Authors: Prakash Chand Negi Ashu Gupta Meena Rana Sanjeev Asotra Neeraj Ganju Rajeev Marwah Rajesh Sharma Arvind Kandoria Source Type: research

Mediterranean diet ‘can reduce heart attacks in people at higher risk’
First study of its kind finds diet can benefit hundreds of millions with obesity, diabetes or other risk factorsA Mediterranean diet can lower the risk of a heart attack, stroke or early death for hundreds of millions of people who have an increased possibility of cardiovascular disease, a global review of evidence suggests.A diet rich in olive oil, nuts, seafood, whole grains and vegetables has previously been linked to a number of benefits, and its effectiveness in helping healthy people to live longer is well known.Continue reading...
Source: Guardian Unlimited Science - March 29, 2023 Category: Science Authors: Andrew Gregory Health editor Tags: Food science Medical research Health & wellbeing Diets and dieting Heart attack Diabetes Life and style Society Source Type: news

Prevalence And Association With Outcomes Of The Espen And Easo-Defined Diagnostic Criteria For Sarcopenic Obesity In Patients Undergoing Rehabilitation After Stroke
Rationale: Sarcopenic obesity, characterized by the coexistence of sarcopenia and obesity, is of growing research and clinical interest; however, validated diagnostic criteria are lacking. Therefore, the purpose of this study was to examine the prevalence of sarcopenic obesity, as diagnosed by the criteria recently proposed by the European Society for Clinical Nutrition and Metabolism (ESPEN) and the European Association for the Study of Obesity (EASO), and its association with outcomes among patients undergoing rehabilitation after stroke.
Source: Clinical Nutrition ESPEN - March 23, 2023 Category: Nutrition Authors: Y. Yoshimura, H. Wakabayashi, F. Nagano, A. Matsumoto, S. Shimazu, A. Shiraishi, Y. Kido, T. Bise Source Type: research

Epicardial adipocytes in the pathogenesis of atrial fibrillation: An update on basic and translational studies
Epicardial adipose tissue (EAT) is an endocrine organ containing a host of cell types and undoubtedly serving a multitude of important physiologic functions. Aging and obesity cause hypertrophy of EAT. There is great interest in the possible connection between EAT and cardiovascular disease, in particular, atrial fibrillation (AF). Increased EAT is independently associated with AF and adverse events after AF ablation (e.g., recurrence of AF, and stroke). In general, the amount of EAT correlates with BMI or visceral adiposity. Yet on a molecular level, there are similarities and differences between epicardial and abdominal ...
Source: Frontiers in Endocrinology - March 20, 2023 Category: Endocrinology Source Type: research

Effect of atherosclerosis on 5-year risk of major vascular events in patients with transient ischaemic attack or minor ischaemic stroke: an international prospective cohort study
Lancet Neurol. 2023 Apr;22(4):320-329. doi: 10.1016/S1474-4422(23)00067-4.ABSTRACTBACKGROUND: The prevalence of atherosclerosis and the long-term risk of major vascular events in people who have had a transient ischaemic attack or minor ischaemic stroke, regardless of the causal relationship between the index event and atherosclerosis, are not well known. In this analysis, we applied the ASCOD (atherosclerosis, small vessel disease, cardiac pathology, other causes, and dissection) grading system to estimate the 5-year risk of major vascular events according to whether there was a causal relationship between atherosclerosis...
Source: Atherosclerosis - March 17, 2023 Category: Cardiology Authors: Philippa C Lavall ée Hugo Charles Gregory W Albers Louis R Caplan Geoffrey A Donnan Jos é M Ferro Michael G Hennerici Julien Labreuche Carlos Molina Peter M Rothwell Philippe Gabriel Steg Pierre-Jean Touboul Shinichiro Uchiyama Éric Vicaut Lawrence K S Source Type: research

Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol
Stephanie Blendermann, 65, had good reason to worry about heart disease. Three of her sisters died in their 40s or early 50s from heart attacks, and her father needed surgery to bypass clogged arteries. She also suffered from an autoimmune disorder that results in chronic inflammation and boosts the odds of developing cardiovascular illnesses. “I have an interesting medical chart,” says Blendermann, a real estate agent in Prior Lake, Minnesota. Yet Blendermann’s routine lab results weren’t alarming. At checkups, her low-density lipoprotein (LDL), or “bad,” cholesterol hovered around the 100 milligrams-per-...
Source: Science of Aging Knowledge Environment - March 16, 2023 Category: Geriatrics Source Type: research

Deep-Learning for Epicardial Adipose Tissue Assessment With Computed  Tomography: Implications for Cardiovascular Risk Prediction
CONCLUSIONS: Automated assessment of EAT volume is possible in CCTA, including in patients who are technically challenging; it forms a powerful marker of metabolically unhealthy visceral obesity, which could be used for cardiovascular risk stratification.PMID:36881425 | DOI:10.1016/j.jcmg.2022.11.018
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Henry W West Muhammad Siddique Michelle C Williams Lucrezia Volpe Ria Desai Maria Lyasheva Sheena Thomas Katerina Dangas Christos P Kotanidis Pete Tomlins Ciara Mahon Attila Kardos David Adlam John Graby Jonathan C L Rodrigues Cheerag Shirodaria John Dean Source Type: research

Young Americans Face Rising Rates of Obesity, High Blood Pressure, Diabetes
MONDAY, March 6, 2023 -- Young adults in the United States carry an increasing burden of heart health risk factors, making it more likely they’ll suffer a heart attack and stroke as they age, a new study warns. More adults ages 20 to 44 are...
Source: Drugs.com - Daily MedNews - March 6, 2023 Category: General Medicine Source Type: news

A Real-World Exploration into Clinical Outcomes of Direct Oral Anticoagulant Dosing Regimens in Morbidly Obese Patients Using Data-Driven Approaches
ConclusionData-driven approaches can identify key factors associated with clinical outcomes following the dosing of DOACs in morbidly obese patients. This will help design further studies to explore well tolerated and effective DOAC doses for morbidly obese patients.
Source: American Journal of Cardiovascular Drugs - March 6, 2023 Category: Cardiology Source Type: research