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Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research

Trans fatty acids and lipid profile: A serious risk factor to cardiovascular disease, cancer and diabetes
The objective of the review to demonstrate the causal association between trans fatty acid intake and increase the risk of coronary heart disease through their influence on lipoprotein, association with atherosclerosis, stroke, diabetes and cancer.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - March 17, 2019 Category: Endocrinology Source Type: research

Lead Anti-obesity Compounds from Nature.
Conclusion-Consumption of diets comprising high amounts of active anti-obesity natural compounds is a promising strategy for the suppression of lipid accumulation and adipogenesis in obese individuals. PMID: 32364084 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - May 2, 2020 Category: Endocrinology Authors: Dahiya V, Vasudeva N, Sharma S, Kumar A, Rowley D Tags: Endocr Metab Immune Disord Drug Targets Source Type: research

Pro-Neurotensin/Neuromedin N and Risk of Incident Metabolic Syndrome and Diabetes Mellitus in the REGARDS Cohort
CONCLUSIONS: Pro-NT/NMN was associated with MetS and two components, dysglycemia and low HDL, likely explained by insulin resistance.PMID:34013344 | DOI:10.1210/clinem/dgab355
Source: The Journal of Clinical Endocrinology and Metabolism - May 20, 2021 Category: Endocrinology Authors: Charles D Nicoli April P Carson Timothy B Plante D Leann Long Leslie A McClure Janin Schulte Mary Cushman Source Type: research

Developmental Origins of Metaflammation; A Bridge to the Future Between the DOHaD Theory and Evolutionary Biology
Metabolic syndrome refers to obesity-associated metabolic disorders that increase the risk of type 2 diabetes, coronary diseases, stroke, and other disabilities. Environmental imbalance during the early developmental period affects health and increases susceptibility to non-communicable diseases, including metabolic syndrome, in later life; therefore, the Developmental Origins of Health and Disease (DOHaD) theory was established. According to the DOHaD theory, the hypothesis of the energy-saving ‘Thrifty Phenotype’ in undernourished fetuses is one of the well-accepted schemes as a risk of developing metabolic syndrome....
Source: Frontiers in Endocrinology - February 3, 2022 Category: Endocrinology Source Type: research