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Specialty: Cardiology
Condition: Cholesterol

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Total 2240 results found since Jan 2013.

Aggressive LDL-C Lowering and the Brain: Impact on Risk for Dementia and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association
The objective of this scientific statement is to evaluate contemporary evidence that either supports or refutes the conclusion that aggressive low-density lipoprotein cholesterol lowering or lipid lowering exerts toxic effects on the brain, leading to cognitive impairment or dementia or hemorrhagic stroke. The writing group used literature reviews, references to published clinical and epidemiology studies, clinical and public health guidelines, authoritative statements, and expert opinion to summarize existing evidence and to identify gaps in current knowledge. Although some retrospective, case control, and prospective lon...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 14, 2023 Category: Cardiology Authors: Larry B Goldstein Peter P Toth Jennifer L Dearborn-Tomazos Robert P Giugliano Benjamin J Hirsh Jessica M Pe ña Magdy H Selim Daniel Woo American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Source Type: research

Predictors of congruency between self-reported hypertension status and measured blood pressure in the stroke belt
Conclusion: Self-report HTN information should be used with caution as an epidemiological investigation tool.
Source: Journal of the American Society of Hypertension - May 28, 2013 Category: Cardiology Authors: Gaurav J. Dave, Daniel L. Bibeau, Mark R. Schulz, Robert E. Aronson, Louise L. Ivanov, Adina Black, LaPronda Spann Tags: Research Articles Source Type: research

The American Heart Association Life's Simple 7 and Incident Cognitive Impairment: The REasons for Geographic And Racial Differences in Stroke (REGARDS) Study Epidemiology
Conclusions Compared with low CVH, intermediate and high CVH were both associated with substantially lower incidence of cognitive impairment. We did not observe a dose-response pattern; people with intermediate and high levels of CVH had similar incidence of cognitive impairment. This suggests that even when high CVH is not achieved, intermediate levels of CVH are preferable to low CVH.
Source: JAHA:Journal of the American Heart Association - June 11, 2014 Category: Cardiology Authors: Thacker, E. L., Gillett, S. R., Wadley, V. G., Unverzagt, F. W., Judd, S. E., McClure, L. A., Howard, V. J., Cushman, M. Tags: Epidemiology Source Type: research

Common Carotid Intima-Media Thickness Relates to Cardiovascular Events in Adults Aged
Although atherosclerosis starts in early life, evidence on risk factors and atherosclerosis in individuals aged <45 years is scarce. Therefore, we studied the relationship between risk factors, common carotid intima-media thickness (CIMT), and first-time cardiovascular events in adults aged <45 years. Our study population consisted of 3067 adults aged <45 years free from symptomatic cardiovascular disease at baseline, derived from 6 cohorts that are part of the USE-IMT initiative, an individual participant data meta-analysis of general-population–based cohort studies evaluating CIMT measurements. Information...
Source: Hypertension - March 11, 2015 Category: Cardiology Authors: Eikendal, A. L. M., Groenewegen, K. A., Anderson, T. J., Britton, A. R., Engstrom, G., Evans, G. W., de Graaf, J., Grobbee, D. E., Hedblad, B., Holewijn, S., Ikeda, A., Kitagawa, K., Kitamura, A., Lonn, E. M., Lorenz, M. W., Mathiesen, E. B., Nijpels, G., Tags: Risk Factors, Imaging, Acute myocardial infarction, Acute Stroke Syndromes, Epidemiology Epidemiology/Population Source Type: research

Comparison of four nontraditional lipid profiles in relation to ischemic stroke among hypertensive Chinese population
Stroke is a major global cause of disability and the second most common cause of death worldwide [1]. In China, stroke is already the leading cause of death and adult disability [2]. Identification of novel predictors is a crucial step to prevent stroke. A growing body of evidence suggests that nontraditional serum lipid variables, including total cholesterol (TC) / high-density lipoprotein cholesterol (HDL-C), triglycerides (TG) / HDL-C, low-density lipoprotein cholesterol (LDL-C) / HDL-C and non-HDL-C, may be better predictors of vascular risk than LDL-C [3–6].
Source: International Journal of Cardiology - August 4, 2015 Category: Cardiology Authors: Xiaofan Guo, Zhao Li, Guozhe Sun, Liang Guo, Liqiang Zheng, Shasha Yu, Hongmei Yang, Guowei Pan, Yonghong Zhang, Yingxian Sun Source Type: research

Long term risk factors for coronary heart disease and stroke: influence of duration of follow-up over four decades of mortality surveillance
Conclusion Despite a general diminution in the strength of effect over time, even in the fourth decade of follow-up, classic risk factors retained some predictive capacity for coronary heart disease and, to a lesser degree, stroke.
Source: European Journal of Preventive Cardiology - August 10, 2015 Category: Cardiology Authors: Batty, G. D., Shipley, M., Smith, G. D., Kivimaki, M. Tags: Original scientific papers Source Type: research

Residual Ischemic Risk and Its Determinants in Patients With Previous Myocardial Infarction and Without Prior Stroke or TIA: Insights From the REACH Registry
ConclusionsIn this study, residual ischemic risk after MI accrued progressively up to 4 years of follow‐up, emphasizing the value of intensive secondary prevention strategies to minimize residual risk.
Source: Clinical Cardiology - July 31, 2016 Category: Cardiology Authors: J érémie Abtan, Deepak L. Bhatt, Yedid Elbez, Emmanuel Sorbets, Kim Eagle, Yasuo Ikeda, David Wu, Mary E. Hanson, Hakima Hannachi, Puneet K. Singhal, Philippe Gabriel Steg, Gregory Ducrocq, Tags: Clinical Investigations Source Type: research

Total cholesterol and stroke mortality in middle-aged and elderly adults: A prospective cohort study
This study aimed to examine the association between total cholesterol (TC) and mortality from total stroke and stroke subtypes.
Source: Atherosclerosis - December 6, 2017 Category: Cardiology Authors: Sang-Wook Yi, Dae-Hee Shin, Hyeyun Kim, Jee-Jeon Yi, Heechol Ohrr Source Type: research

Low Cholesterol Linked to Higher Hemorrhagic Stroke Risk Low Cholesterol Linked to Higher Hemorrhagic Stroke Risk
High LDL cholesterol is a known risk factor for ischemic stroke, but a new study suggests it may also increase the risk for hemorrhagic stroke.Medscape Medical News
Source: Medscape Cardiology Headlines - April 15, 2019 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Treating LDL to Below 70 Reduces Recurrent Stroke Treating LDL to Below 70 Reduces Recurrent Stroke
Results of Treat Stroke to Target (TST), a rare cholesterol study in patients with a history of ischemic stroke, explore the benefits of treating to a lower LDL target.Medscape Medical News
Source: Medscape Cardiology Headlines - November 21, 2019 Category: Cardiology Tags: Cardiology News Source Type: news

Oxidized low-density lipoprotein (LDL) and LDL cholesterol are associated with outcomes of minor stroke and TIA
Low-density lipoprotein (LDL) and oxidized low-density lipoprotein (oxLDL) levels are thought to be related to recurrent stroke. However, the joint association of circulating LDL and oxLDL levels with the outcomes of acute minor ischemic stroke and transient ischemic attack (TIA) remains unclear. The goal of the study was to evaluate whether LDL and oxLDL have a combined effect on outcomes of acute minor stroke and TIA.
Source: Atherosclerosis - February 17, 2020 Category: Cardiology Authors: Anxin Wang, Liye Dai, Nan Zhang, Jinxi Lin, Guojuan Chen, Yingting Zuo, Hao Li, Yilong Wang, Xia Meng, Yongjun Wang Source Type: research

Effect of Intensive and Standard Lipid-Lowering Therapy on the Progression of Stroke in Patients With Coronary Artery Syndromes: A Meta-Analysis of Randomized Controlled Trials
Abstract: This meta-analysis demonstrated the effect of intensive versus standard statins on the risk of stroke in patients with coronary artery syndromes (CAS). PubMed, Embase, the Cochrane library, and clinicaltrials.gov were searched, and the retrieved studies were undertaken for randomized controlled trials (RCTs) throughout September 2018. Studies that were designed as RCTs and recruited at least 1000 CAS patients followed up greater than 1 year were eligible for this study. The summary relative risk with the 95% confidence interval was used as an effect estimate and calculated using the random-effects model. Five R...
Source: Journal of Cardiovascular Pharmacology - March 1, 2020 Category: Cardiology Tags: Original Article Source Type: research

Cardiovascular disease, a major global burden: Epidemiology of stroke and ischemic heart disease in Japan
Glob Health Med. 2021 Dec 31;3(6):358-364. doi: 10.35772/ghm.2020.01113.ABSTRACTJapan ranks the highest globally, in terms of longevity. The average life expectancy was 81.4 years for men and 87.5 years for women in 2019. Such success in health is attributable to the substantial reduction in age-standardized mortality from cardiovascular diseases, especially stroke (136 per 105 in 1980 and 24 per 105 in 2015), when stroke mortality was the highest in the world between the 1960s and the 1990s. On the other hand, ischemic heart disease mortality was the lowest in the world between the 1960s and the 1980s and has continued to...
Source: Atherosclerosis - January 17, 2022 Category: Cardiology Authors: Hiroyasu Iso Source Type: research

Integrated head and neck imaging of symptomatic patients with stroke using simultaneous non-contrast cardiovascular magnetic resonance angiography and intraplaque hemorrhage imaging as compared with digital subtraction angiography
CONCLUSIONS: CMR SNAP is consistent with DSA in measuring vessel diameters and identifying atherosclerosis stenosis in each intracranial and carotid vessel segment. SNAP is also a potential alternative to HR-VWI in identifying stenosis and IPH.PMID:35307027 | DOI:10.1186/s12968-022-00849-1
Source: Atherosclerosis - March 21, 2022 Category: Cardiology Authors: Yuxi Jia Xiaoming Liu Lan Zhang Xiangchuang Kong Shuo Chen Lei Zhang Jiazheng Wang Shenglei Shu Jia Liu Xiaona Fu Dingxi Liu Jing Wang Heshui Shi Source Type: research