Filtered By:
Condition: Cholesterol
Nutrition: Vitamins
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1962 results found since Jan 2013.
Effect of oral versus parenteral vitamin D3 supplementation on nuclear factor- κB and platelet aggregation in type 2 diabetic patients
In conclusion, restoring normal levels of vitamin D is an important determinant to maintain normal platelet function and reduce inflammation. Nevertheless, further long-term studies are still needed.PMID:37721213 | DOI:10.1139/cjpp-2022-0359
Source: Canadian Journal of Physiology and Pharmacology - September 18, 2023 Category: Drugs & Pharmacology Authors: Esraa Habiba Samia Ali Yehia Ghanem Ola Sharaki Wafaa Hewedy Source Type: research
Genomically anchored vitamin D receptor mediates an abundance of bioprotective actions elicited by its 1,25-dihydroxyvitamin D hormonal ligand
Vitam Horm. 2023;123:313-383. doi: 10.1016/bs.vh.2022.12.008. Epub 2023 Jun 8.ABSTRACTThe nuclear vitamin D receptor (VDR) mediates the actions of its physiologic 1,25-dihydroxyvitamin D3 (1,25D) ligand produced in kidney and at extrarenal sites during times of physiologic and cellular stress. The ligand-receptor complex transcriptionally controls genes encoding factors that regulate calcium and phosphate sensing/transport, bone remodeling, immune function, and nervous system maintenance. With the aid of parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23), 1,25D/VDR primarily participates in an intricate netw...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Mark R Haussler Carol A Haussler Peter W Jurutka Source Type: research
A structural perspective of liver X receptors
Vitam Horm. 2023;123:231-247. doi: 10.1016/bs.vh.2023.01.008. Epub 2023 Feb 6.ABSTRACTLiver X receptors α and β are members of the nuclear receptor family, which comprise a flexible N-terminal domain, a DNA binding domain, a hinge linker, and a ligand binding domain. Liver X receptors are important regulators of cholesterol and lipid homeostasis by controlling the transcription of numerous genes. Key to their transcriptional role is synergetic interaction among the domains. DNA binding domain binds on DNA; ligand binding domain is a crucial switch to control the transcription activity through conformational change caused...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Jan- Åke Gustafsson Xian Chang Li Ji Ho Suh Xiaohua Lou Source Type: research
Genomically anchored vitamin D receptor mediates an abundance of bioprotective actions elicited by its 1,25-dihydroxyvitamin D hormonal ligand
Vitam Horm. 2023;123:313-383. doi: 10.1016/bs.vh.2022.12.008. Epub 2023 Jun 8.ABSTRACTThe nuclear vitamin D receptor (VDR) mediates the actions of its physiologic 1,25-dihydroxyvitamin D3 (1,25D) ligand produced in kidney and at extrarenal sites during times of physiologic and cellular stress. The ligand-receptor complex transcriptionally controls genes encoding factors that regulate calcium and phosphate sensing/transport, bone remodeling, immune function, and nervous system maintenance. With the aid of parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23), 1,25D/VDR primarily participates in an intricate netw...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Mark R Haussler Carol A Haussler Peter W Jurutka Source Type: research
A structural perspective of liver X receptors
Vitam Horm. 2023;123:231-247. doi: 10.1016/bs.vh.2023.01.008. Epub 2023 Feb 6.ABSTRACTLiver X receptors α and β are members of the nuclear receptor family, which comprise a flexible N-terminal domain, a DNA binding domain, a hinge linker, and a ligand binding domain. Liver X receptors are important regulators of cholesterol and lipid homeostasis by controlling the transcription of numerous genes. Key to their transcriptional role is synergetic interaction among the domains. DNA binding domain binds on DNA; ligand binding domain is a crucial switch to control the transcription activity through conformational change caused...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Jan- Åke Gustafsson Xian Chang Li Ji Ho Suh Xiaohua Lou Source Type: research
Genomically anchored vitamin D receptor mediates an abundance of bioprotective actions elicited by its 1,25-dihydroxyvitamin D hormonal ligand
Vitam Horm. 2023;123:313-383. doi: 10.1016/bs.vh.2022.12.008. Epub 2023 Jun 8.ABSTRACTThe nuclear vitamin D receptor (VDR) mediates the actions of its physiologic 1,25-dihydroxyvitamin D3 (1,25D) ligand produced in kidney and at extrarenal sites during times of physiologic and cellular stress. The ligand-receptor complex transcriptionally controls genes encoding factors that regulate calcium and phosphate sensing/transport, bone remodeling, immune function, and nervous system maintenance. With the aid of parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23), 1,25D/VDR primarily participates in an intricate netw...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Mark R Haussler Carol A Haussler Peter W Jurutka Source Type: research
A structural perspective of liver X receptors
Vitam Horm. 2023;123:231-247. doi: 10.1016/bs.vh.2023.01.008. Epub 2023 Feb 6.ABSTRACTLiver X receptors α and β are members of the nuclear receptor family, which comprise a flexible N-terminal domain, a DNA binding domain, a hinge linker, and a ligand binding domain. Liver X receptors are important regulators of cholesterol and lipid homeostasis by controlling the transcription of numerous genes. Key to their transcriptional role is synergetic interaction among the domains. DNA binding domain binds on DNA; ligand binding domain is a crucial switch to control the transcription activity through conformational change caused...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Jan- Åke Gustafsson Xian Chang Li Ji Ho Suh Xiaohua Lou Source Type: research
Efficacy of Vitamin D < sub > 2 < /sub > in maintaining serum total vitamin D concentrations and bone mineralization in adult dogs fed a plant-based (vegan) diet in a three-month randomized trial
Br J Nutr. 2023 Sep 6:1-41. doi: 10.1017/S0007114523001952. Online ahead of print.ABSTRACTDogs are considered omnivores based on their evolution, consuming diets that include animal tissue. Few feeding trials evaluating the nutritional suitability of exclusively plant-based (vegan) diets in dogs have been published, and the efficacy of vitamin D2 in maintaining canine serum vitamin D levels has not been clearly determined. A blinded dietary trial included 61 healthy desexed adult dogs: 31 fed an experimental extruded vegan diet (PLANT) and 30 fed a commercial extruded meat-based diet (MEAT) for three months. Dogs were scre...
Source: The British Journal of Nutrition - September 6, 2023 Category: Nutrition Authors: Sarah As Dodd Jennifer Adolphe Cate Dewey Deep Khosa Sarah K Abood Adronie Verbrugghe Source Type: research
Comparison of individuals doing sports in indoor and outdoor areas and sedentary individuals in terms of vitamin D, body fat content, and obesity values
CONCLUSIONS: Sport has a positive effect on body mass index and serum cholesterol levels. Outdoor sports have a more positive effect on the vit 25-OH levels and serum lipid profile than indoor sports.PMID:37667916 | DOI:10.26355/eurrev_202308_33391
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: S Çetin Daglı S Tunal ı Çokluk Z Ozkan Z Pancar Source Type: research
The magic of a methyl group: biochemistry at the service of medicine
Biochem Pharmacol. 2023 Sep 1:115786. doi: 10.1016/j.bcp.2023.115786. Online ahead of print.ABSTRACTA carbon-carbon linkage is created when a methyl group is implanted on dUMP, thus resulting in the formation of dTMP by thymidylate synthase. The methyl group is deleted by aromatase when androgens are converted to estrogens. The methyl group is rearranged with the help of vitamin B12 in the isomerization of methylmalonyl-CoA to succinyl-CoA. S-adenosylmethionine (SAM) serves as the universal methyl donor involved in the biosynthesis of adrenaline and creatine(phosphate). It also interferes with the 5'-mRNA capping and the d...
Source: Biochemical Pharmacology - September 3, 2023 Category: Drugs & Pharmacology Authors: Erik De Clercq Source Type: research
The necessity for improving lipid testing reagents: A real world study
CONCLUSION: VitC, glycerol fructose, LpX and lipemia significantly interfered with lipid assays. The reagent formulation should be improved to get reliable results.PMID:37640131 | DOI:10.1016/j.cca.2023.117529
Source: International Journal of Clinical Chemistry - August 28, 2023 Category: Chemistry Authors: Chuan Zheng Weiyan Zhou Ruyi Zhou He Zhang Shanshan Liang Wen Zhang GuiXing Li Chuanbao Zhang Wei Gan Source Type: research
