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Combining ultrasound with bio-indicators reveals progression of carotid stenosis
CONCLUSIONS: High-risk hs-CRP and hypoechoic plaque are independently associated with CAS progression. The progression of carotid stenosis is associated with a high risk of cerebrovascular events.PMID:34872279 | DOI:10.21037/apm-21-2666
Source: Atherosclerosis - December 7, 2021 Category: Cardiology Authors: Mingjian Liu Ziqian Zhang Yan Zhao Zhenghong Chen Bin Chen Yongxu Wei Yijun Cheng Lifeng Zhu Dehua Chen Derong Cui Hanbing Shang Source Type: research

Lowering Targeted Atherogenic Lipoprotein Cholesterol Goals for Patients at “Extreme” ASCVD Risk
AbstractPurpose of ReviewTo review randomized interventional clinical and imaging trials that support lower targeted atherogenic lipoprotein cholesterol goals in “extreme” and “very high” atherosclerotic cardiovascular disease (ASCVD) risk settings. Major atherosclerotic cardiovascular event (MACE) prevention among the highest risk patients with ASCVD requires aggressive management of global risks, including lowering of the fundamental atherogenic ap olipoprotein B-associated lipoprotein cholesterol particles [i.e., triglyceride-rich lipoprotein remnant cholesterol, low-density lipoprotein cholesterol (LDL-C), and ...
Source: Current Diabetes Reports - November 20, 2019 Category: Endocrinology Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Stroke associated with coronary artery bypass grafting
Abstract While coronary artery bypass grafting (CABG) has been playing a significant role in the revascularization for ischemic heart disease, neurological complications associated with CABG have been a primary concern. Stroke, although the incidence is low, is one of the most devastating complication of CABG. Many studies have identified the risk factors for stroke with CABG, such as prior stroke, carotid artery stenosis, aortic atherosclerosis, atrial fibrillation and cardiopulmonary bypass. Various rational approaches focusing on individual risk factor have been proposed for the stroke. Prophylactic carotid rev...
Source: General Thoracic and Cardiovascular Surgery - July 7, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Vascular Ultrasound Imaging for Screening Patients at Risk for Cardiovascular Events
Carotid intima-media thickness (IMT) has been proposed as a useful predictor of cardiovascular (CV) events in asymptomatic subjects in prospective observational studies, and has been used as a surrogate marker of efficacy in randomized therapeutic trials of statins [1]. Furthermore, meta-analyses have demonstrated incremental coronary heart disease and stroke risk prediction with IMT [2]. The evidence emerging from numerous observational, interventional, and meta-analytical studies led, at the AHA Prevention Conference V, to the recommendation of the use of “carefully performed carotid ultrasound in experienced laborator...
Source: CVD Prevention and Control - December 1, 2014 Category: Cardiology Authors: Tasneem Z. Naqvi Tags: Editorial Comment Source Type: research