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Condition: Heart Disease
Procedure: Heart Valve Surgery

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Total 250 results found since Jan 2013.

Impact of Flow and Left Ventricular Strain on Outcome of Patients With Preserved Left Ventricular Ejection Fraction and Low Gradient Severe Aortic Stenosis Undergoing Aortic Valve Replacement
The prognostic implications of flow, assessed by stroke volume index (SVi), and left ventricular (LV) global longitudinal strain on survival of patients with low-gradient severe aortic stenosis (AS) and preserved LV ejection fraction are debated. The aim of this study was to evaluate the impact of flow and LV global longitudinal strain on survival in these patients treated with aortic valve replacement (AVR). Patients with low-gradient severe AS with preserved LV ejection fraction treated with AVR (n = 134, mean age 76 ± 10 years, 50% men) were included in the present study.
Source: The American Journal of Cardiology - September 25, 2014 Category: Cardiology Authors: Vasileios Kamperidis, Philippe J. van Rosendael, Arnold C.T. Ng, Spyridon Katsanos, Frank van der Kley, Philippe Debonnaire, Emer Joyce, Georgios Sianos, Nina Ajmone Marsan, Jeroen J. Bax, Victoria Delgado Tags: Valvular Heart Disease Source Type: research

Importance of Exercise Capacity in Predicting Outcomes and Determining Optimal Timing of Surgery in Significant Primary Mitral Regurgitation Valvular Heart Disease
Conclusion In patients with primary MR that underwent exercise echocardiography followed by MV surgery, lower achieved metabolic equivalents were associated with worse long-term outcomes. In those with preserved exercise capacity, delaying MV surgery by ≥1 year did not adversely affect outcomes.
Source: JAHA:Journal of the American Heart Association - September 11, 2014 Category: Cardiology Authors: Naji, P., Griffin, B. P., Barr, T., Asfahan, F., Gillinov, A. M., Grimm, R. A., Rodriguez, L. L., Mihaljevic, T., Stewart, W. J., Desai, M. Y. Tags: Valvular Heart Disease Source Type: research

Anti-streptokinase antibodies and outcome of fibrinolytic therapy with streptokinase for left-sided prosthetic valve thrombosis
Conclusion Anti-SK antibody titres are not associated with success of fibrinolytic therapy using SK in patients with left-sided PVT.
Source: American Heart Journal - October 31, 2014 Category: Cardiology Source Type: research

Approach to the new oral anticoagulants in family practice: Part 2: addressing frequently asked questions.
CONCLUSION: Management of "what if" scenarios for patients taking NOACs have been proposed, but additional study is needed to address these issues, especially periprocedural management and bleeding. PMID: 25392439 [PubMed - as supplied by publisher]
Source: Canadian Family Physician Medecin de Famille Canadien - November 1, 2014 Category: Primary Care Authors: Douketis J, Bell AD, Eikelboom J, Liew A Tags: Can Fam Physician Source Type: research

Antistreptokinase antibodies and outcome of fibrinolytic therapy with streptokinase for left-sided prosthetic valve thrombosis
Conclusion Anti-SK antibody titers are not associated with success of fibrinolytic therapy using SK in patients with left-sided PVT.
Source: American Heart Journal - November 17, 2014 Category: Cardiology Source Type: research

Have antibiotic changes upped heart infections?
Conclusion This is valuable and timely research, which has looked at trends before and after NICE's 2008 guidance on the prevention of infective endocarditis in people undergoing invasive procedures. This examined: changes in the prescription of antibiotics for the prevention of infective endocarditis changes in the number of cases of infective endocarditis diagnosed NICE's recommendation was based on an examination of the evidence of the effectiveness of antibiotics in preventing infective endocarditis, weighing the benefits and health outcomes (such as reduction in illness and deaths), risks and costs.   The ...
Source: NHS News Feed - November 19, 2014 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news

Transcatheter aortic valve implantation.
Authors: Oliemy A, Al-Attar N Abstract Transcatheter aortic valve implantation was developed to offer a therapeutic solution to patients with severe symptomatic aortic stenosis who are not candidates for conventional aortic valve replacement. The improvement in transcatheter aortic valve implantation outcomes is still of concern in the areas of stroke, vascular injury, heart block, paravalvular regurgitation and valve durability. Concomitantly, the progress, both technical and in terms of material advances of transcatheter valve systems, as well as in patient selection, renders transcatheter aortic valve implantati...
Source: F1000 Medicine Reports - December 1, 2014 Category: Biomedical Science Tags: F1000Prime Rep Source Type: research

Aortic stenosis: flow matters
The presence of a low transvalvular pressure gradient (<40 mm Hg) in conjunction with a small aortic valve area (AVA ≤1 cm2) is a challenging situation as it raises uncertainty about the actual severity of aortic stenosis (AS) and therefore about the indication of aortic valve replacement (AVR) if the patient is symptomatic. This low-gradient ‘severe’ (small AVA) AS entity may in fact be related to: (i) measurement errors: underestimation of stroke volume (SV), AVA and/or gradient;S1 (ii) small body size: a small AVA in a small patient may correspond to moderate AS and low gradient; (iii) i...
Source: Heart - December 12, 2014 Category: Cardiology Authors: Pibarot, P. Tags: Drugs: cardiovascular system, Echocardiography, Hypertension, Aortic valve disease, Mitral valve disease, Right sided valvular heart disease, Clinical diagnostic tests, Epidemiology Editorials Source Type: research

Long-Term Results of Transapical Versus Transfemoral TAVI in a Real World Population of 1000 Patients With Severe Symptomatic Aortic Stenosis Structural Heart Disease
Conclusions— The data demonstrate that in an experienced multidisciplinary heart team, either access route can be performed with comparable results.
Source: Circulation: Cardiovascular Interventions - December 31, 2014 Category: Cardiology Authors: Schymik, G., Wurth, A., Bramlage, P., Herbinger, T., Heimeshoff, M., Pilz, L., Schymik, J. S., Wondraschek, R., Suselbeck, T., Gerhardus, J., Luik, A., Gonska, B.-D., Posival, H., Schmitt, C., Schrofel, H. Tags: CV surgery: valvular disease Structural Heart Disease Source Type: research

Impact of exercise pulmonary hypertension on postoperative outcome in primary mitral regurgitation
Conclusions ExPHT is associated with increased risk of adverse cardiac events following mitral valve surgery in patients with primary MR.
Source: Heart - February 12, 2015 Category: Cardiology Authors: Magne, J., Donal, E., Mahjoub, H., Miltner, B., Dulgheru, R., Thebault, C., Pierard, L. A., Pibarot, P., Lancellotti, P. Tags: Drugs: cardiovascular system, Echocardiography, Hypertension, Mitral valve disease, Clinical diagnostic tests Valvular heart disease Source Type: research

Paravalvular regurgitation after transcatheter aortic valve replacement with the Edwards sapien valve in the PARTNER trial: characterizing patients and impact on outcomes
Conclusion Differences in baseline characteristics in patients with increasing severities of PVR may increase the risk of this complication. Despite these differences, multivariable analysis demonstrated that both mild and moderate/severe PVR predicted higher 1-year mortality.
Source: European Heart Journal - February 14, 2015 Category: Cardiology Authors: Kodali, S., Pibarot, P., Douglas, P. S., Williams, M., Xu, K., Thourani, V., Rihal, C. S., Zajarias, A., Doshi, D., Davidson, M., Tuzcu, E. M., Stewart, W., Weissman, N. J., Svensson, L., Greason, K., Maniar, H., Mack, M., Anwaruddin, S., Leon, M. B., Hah Tags: Valvular heart disease Source Type: research

Effect of Left Ventricular Ejection Fraction on Postoperative Outcome in Patients With Severe Aortic Stenosis Undergoing Aortic Valve Replacement Valvular Heart Disease
Conclusions— LVEF is a powerful predictor of outcome in patients with severe aortic stenosis undergoing aortic valve replacement, independent of the presence of valve-related symptoms.
Source: Circulation: Cardiovascular Imaging - April 7, 2015 Category: Radiology Authors: Dahl, J. S., Eleid, M. F., Michelena, H. I., Scott, C. G., Suri, R. M., Schaff, H. V., Pellikka, P. A. Tags: Contractile function, Valvular heart disease, Echocardiography, CV surgery: valvular disease Source Type: research

Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study)
Conclusion Rheumatic heart disease patients were young, predominantly female, and had high prevalence of major cardiovascular complications. There is suboptimal utilization of secondary antibiotic prophylaxis, oral anti-coagulation, and contraception, and variations in the use of percutaneous and surgical interventions by country income level.
Source: European Heart Journal - May 7, 2015 Category: Cardiology Authors: Zuhlke, L., Engel, M. E., Karthikeyan, G., Rangarajan, S., Mackie, P., Cupido, B., Mauff, K., Islam, S., Joachim, A., Daniels, R., Francis, V., Ogendo, S., Gitura, B., Mondo, C., Okello, E., Lwabi, P., Al-Kebsi, M. M., Hugo-Hamman, C., Sheta, S. S., Haile Tags: Valvular heart disease Source Type: research

Paradoxical low-flow, low-gradient severe aortic stenosis: a distinct disease entity
Low-flow, low-gradient (LFLG) severe aortic stenosis (AS), despite preserved LVEF, that is, paradoxical LFLG, is one of the most challenging entities in valvular heart disease.1 Hachicha et al were the first to report that patients with small aortic valve area (AVA) and preserved LVEF may concomitantly have an LF and thus often low gradient.1 This new entity is defined as an AVA ≤1.0 cm2 or indexed AVA ≤0.6 cm2/m2, a mean pressure gradient (MPG) <40 mm Hg, an LVEF ≥50% and a stroke volume index (SVi) <35 mL/m2. The most recent European2 and American3 guidelines have recognised parado...
Source: Heart - June 10, 2015 Category: Cardiology Authors: Magne, J., Mohty, D. Tags: Drugs: cardiovascular system, Echocardiography, Aortic valve disease, Right sided valvular heart disease, Clinical diagnostic tests Editorials Source Type: research

Evolution and prognostic impact of low flow after transcatheter aortic valve replacement
Conclusions The measurement of EP-SVi is useful to assess the immediate haemodynamic benefit of TAVR and to predict the risk of late mortality.
Source: Heart - July 9, 2015 Category: Cardiology Authors: Le Ven, F., Thebault, C., Dahou, A., Ribeiro, H. B., Capoulade, R., Mahjoub, H., Urena, M., Nombela-Franco, L., Allende Carrera, R., Clavel, M.-A., Dumont, E., Dumesnil, J., De Larochelliere, R., Rodes-Cabau, J., Pibarot, P. Tags: Drugs: cardiovascular system, Echocardiography, Clinical diagnostic tests, Epidemiology Valvular heart disease Source Type: research