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Similar 5-year clinical outcomes in patients with stable coronary artery disease and myocardial ischaemia managed with an initial approach of medical therapy compared with medical therapy plus percutaneous coronary intervention
Commentary on: Stergiopoulos K, Boden WE, Hartigan P, et al.. Percutaneous coronary intervention outcomes in patients with stable obstructive coronary artery disease and myocardial ischaemia: a collaborative meta-analysis of contemporary randomized clinical trials. JAMA Intern Med 2014;174:232–40. Context In patients with stable coronary artery disease (CAD), the presence of myocardial ischaemia is associated with increased cardiac event rates. Percutaneous coronary intervention (PCI) achieves greater short-term reductions in myocardial ischaemia and angina than medical therapy. In contrast to patients with acute cor...
Source: Evidence-Based Medicine - September 15, 2014 Category: Internal Medicine Authors: Archbold, R. A. Tags: Clinical trials (epidemiology), Epidemiologic studies, Drugs: cardiovascular system, Stroke, Interventional cardiology, Ischaemic heart disease, Radiology, Clinical diagnostic tests, Radiology (diagnostics) Therapeutics Source Type: research

Medtronic Sponsors American Diabetes Association Educational Campaign "Make the Link" for 2nd Year
To help educate people about this connection with heart disease, and provide materials to help with prevention, as well as treatment, Medtronic has announced that it is continuing its sponsorship of the American Diabetes Association's Make the Link! Diabetes, Heart Disease and Stroke initiative for a second year. The "Make the Link" website has a series of downloadable information packets to help educate people about diabetes and coronary artery disease (CAD).
Source: News from Angioplasty.Org - November 14, 2014 Category: Cardiology Source Type: news

Long-term follow-up results in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents: results from a single high-volume PCI centre
Conclusions PCI patients with STEMI had the worst hospital and long-term prognosis. The mortality rate after hospital increased markedly in patients with NSTE-ACS. SESs seem to be more effective than PESs.
Source: BMJ Open - August 11, 2014 Category: Journals (General) Authors: Yao, H.-M., Wan, Y.-D., Zhang, X.-J., Shen, D.-L., Zhang, J.-Y., Li, L., Zhao, L.-S., Sun, T.-W. Tags: Open access, Cardiovascular medicine, Surgery Research Source Type: research

Optimal medical therapy for coronary artery disease in 2011 - perspectives from the STICH Trial.
Authors: Whayne TF, Saha SP, Quevedo K, Mukherjee D Abstract Medical, percutaneous interventional, and surgical treatments for the management of coronary heart disease have progressed markedly during the past decade. There is evidence to suggest that for patients with stable coronary heart disease optimal medical therapy is equal in effectiveness for lowering the risk of major cardiovascular events, such as cardiovascular death, myocardial infarction, and stroke, as are revascularization procedures, such as coronary artery bypass grafting or percutaneous coronary intervention. The landmark Surgical Treatment for Is...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - November 23, 2014 Category: Cardiology Tags: Cardiovasc Hematol Agents Med Chem Source Type: research

Anemia and inflammation have an additive value in risk stratification of patients undergoing coronary interventions
Aims: Anemia and inflammation are both associated with unfavorable outcomes in patients with ischemic heart disease and might be pathophysiologically linked. We aimed to analyze the additive value of anemia and inflammation on the outcomes of patients undergoing percutaneous coronary intervention. Methods: Cox regression models were fitted for hemoglobin and C-reactive protein (CRP) cut-offs and performed separately for myocardial infarction (MI) and angina pectoris patients undergoing catheterization at a tertiary hospital between 2006 and 2011. Major adverse cardiovascular events (MACEs) were defined as all-cause mortali...
Source: Journal of Cardiovascular Medicine - January 2, 2015 Category: Cardiology Tags: Original articles: Coronary revascularization Source Type: research

Meta-analysis compares anticoagulant strategies in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention
Commentary on: Bangalore S, Toklu B, Kotwal A, et al. Anticoagulant therapy during primary percutaneous coronary intervention for acute myocardial infarction: a meta-analysis of randomised trials in the era of stents and P2Y12 inhibitors. BMJ 2014;349:g6419 Context Optimal anticoagulant therapy in patients receiving primary intervention for acute myocardial infarction (MI) is widely debated. Prior studies have been heterogeneous in doses and concomitant treatments such that it has been unclear whether effects have been those of newer medication or a result of changes in these co-interventions. A meta-analytic approach can ...
Source: Evidence-Based Medicine - March 17, 2015 Category: Internal Medicine Authors: Patti, G. Tags: Clinical trials (epidemiology), Drugs: cardiovascular system, Stroke, Interventional cardiology, Ischaemic heart disease, Venous thromboembolism, Radiology, Clinical diagnostic tests Therapeutics/Prevention Source Type: research

Fasting may not be required before percutaneous coronary intervention
Commentary on: Hamid T, Aleem Q, Lau Y, et al.. Pre-procedural fasting for coronary interventions: is it time to change practice? Heart 2014;100:658–61. Implications for practice and research The results of this study suggest that percutaneous coronary intervention (PCI) can be safely conducted without preprocedural fasting. Revision is needed of current fasting protocols. The findings of Hamid and colleagues must be confirmed by further randomised trials. Context PCI is currently performed in hospitals around the world. This procedure is generally conducted with light sedation and local anaesthesia. Patients are rou...
Source: Evidence-Based Nursing - March 19, 2015 Category: Nursing Authors: de Aguilar-Nascimento, J. E., Feguri, G. R. Tags: Adult nursing, Pneumonia (infectious disease), TB and other respiratory infections, Stroke, Diet, Interventional cardiology, Ischaemic heart disease, Cardiothoracic surgery, Vascular surgery Source Type: research

Coronary heart disease in moyamoya disease: are they concomitant or coincidence?
Abstract The purpose of this study was to determine the prevalence and characteristics of symptomatic coronary heart disease (CHD) in patients with moyamoya disease (MMD). This retrospective study evaluated 456 patients who received examination for MMD between 1995 and 2012. We reviewed the patients' medical history and coronary imaging, including conventional coronary angiography and coronary computed tomography angiogram (CTA). Among 456 patients with MMD, 21 (4.6%) patients were found to have symptomatic CHD. Ten patients were treated with coronary artery bypass graft or percutaneous coronary intervention for u...
Source: J Korean Med Sci - April 1, 2015 Category: Journals (General) Authors: Nam TM, Jo KI, Yeon JY, Hong SC, Kim JS Tags: J Korean Med Sci Source Type: research

0018 : Antithrombotic management in patients with atrial fibrillation undergoing stent implantation: An assessment of the ESC guidelines adherence
Conclusion Guidelines for antithrombotic therapy in patients with AF who undergo PCI and stent implantation are still poorly followed in clinical practice. OAC underused was associated with an increased risk of death in this population.
Source: Archives of Cardiovascular Diseases Supplements - May 8, 2015 Category: Cardiology Source Type: research

Abstract 263: Incidence of Recurrent Cardiovascular Events and Disease Burden Among High-Risk Patients with Hyperlipidemia Session Title: Poster Session II
Conclusions: CV event-related risk and long-term costs are significantly greater among high-risk patients with shorter time intervals between recurrent CV events. Underutilization of LLTs in these patients highlights the need for improving clinical management and treatment options for these patients.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Punekar, R. S., Fox, K. M., Richhariya, A., Fisher, M. D., Gandra, S. R., Cziraky, M. J., Toth, P. P. Tags: Session Title: Poster Session II Source Type: research

Coronary artery bypass surgery continues to remain the treatment of choice for multivessel coronary artery disease even in the era of new-generation drug-eluting stents
Commentary on: Park SJ, Ahn JM, Kim YH, et al; BEST Trial Investigators. Trial of everolimus-eluting stents or bypass surgery for coronary disease. N Engl J Med 2015;372:1204–12. Context Multivessel coronary artery disease (MVCAD) may be found in patients subjected to coronary angiography. It is treated with coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI). The expanded use of PCI, following development of drug-eluting stents (DES), necessitated comparison of its outcomes with CABG (gold standard therapy). The SYNTAX (SYNergy between PCI with TAXUS and Cardiac Surgery) trial favoured...
Source: Evidence-Based Medicine - July 24, 2015 Category: Internal Medicine Authors: Mohr, F. W., Davierwala, P. M. Tags: Clinical trials (epidemiology), Drugs: cardiovascular system, Stroke, Interventional cardiology, Ischaemic heart disease, Venous thromboembolism, Radiology, Clinical diagnostic tests, Radiology (diagnostics) Therapeutics/Prevention Source Type: research

Cardiovascular Disease Treatment Outcomes in Patients with Diabetes: Prediction Models Using Artificial Neural Networks and Logistic Regression
Diabetes mellitus (DM) is not only a major risk factor for coronary heart disease (CHD); it also worsens CHD prognosis. The study's purpose was to investigate comparative effectiveness of two major CHD treatment procedures - coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) - in a population of CHD patients with DM (CHD-DM), using an artificial intelligence tool - artificial neural networks (ANN) - and a traditional multivariable logistic regression (MLR).
Source: Annals of Epidemiology - August 21, 2015 Category: Epidemiology Authors: Alexander V. Sergeev, Gary R. Weckman Tags: Cardiovascular Diseases and Stroke Source Type: research

Right care and high-value cardiology: doctors' responsibilities to the patient and the population
Significant advances in cardiovascular care, developed over the past three decades, are now routine treatment for people with heart disease—for example, primary angioplasty for acute ST elevation myocardial infarction is available to over 70% of the UK population, resynchronisation and defibrillator pacing devices are options for those with advanced heart failure, and drug therapies such as statins for secondary prevention have made significant impacts in reducing cardiovascular mortality in the past 50 years. Today, patients with cardiovascular disease can expect a better quality of life and greater longevity t...
Source: Postgraduate Medical Journal - August 24, 2015 Category: Journals (General) Authors: Malhotra, A., Apps, A., Saini, V., Gray, M. Tags: Patients, General practice / family medicine, Drugs: cardiovascular system, Stroke, Interventional cardiology, Ischaemic heart disease, Radiology, Clinical diagnostic tests, Cardiothoracic surgery, Vascular surgery, Epidemiology, Health economics Editor Source Type: research

Lean body mass index prognostic value for cardiovascular events in patients with coronary artery disease
Conclusions Lower LBMI values are associated with adverse outcomes in an Asian population with CHD undergoing PCI. LBMI is a better predictor of MACE than BMI or FMI. Clinical trial registration UMIN-ID; 000010070.
Source: Heart Asia - August 26, 2015 Category: Cardiology Authors: Hioki, H., Miura, T., Motoki, H., Kobayashi, H., Kobayashi, M., Nakajima, H., Kimura, H., Mawatari, E., Akanuma, H., Sato, T., Ebisawa, S., Miyashita, Y., Ikeda, U., On behalf of the SHINANO registry investigators, On behalf of the SHINANO registry invest Tags: Open access Cardiac risk factors and prevention Source Type: research

A retrospective cross-sectional study on the association between tobacco smoking and incidence of ST-segment elevation myocardial infarction and cardiovascular risk factors
Conclusion Cigarette smoking is associated with a fivefold increased risk of STEMI. Smoking cessation reduced this risk to a level similar to never-smokers.
Source: Postgraduate Medical Journal - September 2, 2015 Category: Journals (General) Authors: Steele, L., Lloyd, A., Fotheringham, J., Sultan, A., Iqbal, J., Grech, E. D. Tags: Drugs: cardiovascular system, Stroke, Interventional cardiology, Ischaemic heart disease, Cardiothoracic surgery, Vascular surgery, Epidemiology Original article Source Type: research

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