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Association of urinary nitrate with diabetes complication and disease-specific mortality among adults with hyperglycemia
CONCLUSIONS: Higher urinary nitrate is associated with lower risk of congestive heart failure and diabetic nephropathy, and lower risk of all-cause, CVD, and diabetes mortalities. These findings indicated that inorganic nitrate supplementation can be considered as a supplementary treatment for people with hyperglycemia.PMID:36576885 | DOI:10.1210/clinem/dgac741
Source: The Journal of Clinical Endocrinology and Metabolism - December 28, 2022 Category: Endocrinology Authors: Wenbo Jiang Jia Zhang Ruiming Yang Xinyi Sun Huanyu Wu Jiacheng Zhang Siyao Liu Changhao Sun Lifang Ma Tianshu Han Wei Wei Source Type: research

Hepatic-Metabolite-Based Intermittent Fasting Enables a Sustained Reduction in Insulin Resistance in Type 2 Diabetes and Metabolic Syndrome
Horm Metab Res DOI: 10.1055/a-1510-8896Insulin resistance is the hallmark of Type 2 Diabetes and is still an unmet medical need. Insulin resistance lies at the crossroads of non-alcoholic fatty liver disease, obesity, weight loss and exercise resistance, heart disease, stroke, depression, and brain health. Insulin resistance is purely nutrition related, with a typical molecular disease food intake pattern. The insulin resistant state is accessible by TyG as the appropriate surrogate marker, which is found to lead the personalized molecular hepatic nutrition system for highly efficient ins...
Source: Hormone and Metabolic Research - June 30, 2021 Category: Endocrinology Authors: Rohner, Markus Heiz, Robert Feldhaus, Simon Bornstein, Stefan R. Tags: Endocrine Care Source Type: research

Meal Timing of Subtypes of Macronutrients Consumption With Cardiovascular Diseases: NHANES, 2003 to 2016
CONCLUSION: This study indicated that overconsumption of low-quality carbohydrates and animal protein at dinner rather than breakfast was significantly associated with higher CVD risk and USFA consumption at dinner related to lower CVD risk among US adults. Substitution of low-quality carbohydrates or animal protein by high-quality carbohydrates or plant protein at dinner could reduce CVD risk.PMID:34038544 | DOI:10.1210/clinem/dgab288
Source: The Journal of Clinical Endocrinology and Metabolism - May 26, 2021 Category: Endocrinology Authors: Wanying Hou Jian Gao Wenbo Jiang Wei Wei Huanyu Wu Yuntao Zhang Changhao Sun Ying Li Tianshu Han Source Type: research

The dietary transition and its association with cardiometabolic mortality among Chinese adults, 1982–2012: a cross-sectional population-based study
Publication date: Available online 10 May 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Yuna He, Yanping Li, Xiaoguang Yang, Elena C Hemler, Yuehui Fang, Liyun Zhao, Jian Zhang, Zhenyu Yang, Zhu Wang, Li He, Jing Sun, Dong D Wang, Jingzhong Wang, Jianhua Piao, Xiaofeng Liang, Gangqiang Ding, Frank B HuSummaryBackgroundFew studies have used nationally representative data to describe dietary trends and the related cardiometabolic mortality burden in China. Thus, we aimed to characterise the trends in disease-related dietary factors as well as their associated disease burden among Chinese adults from 1982 to 2012....
Source: The Lancet Diabetes and Endocrinology - May 12, 2019 Category: Endocrinology Source Type: research

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research