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Clinical Features and Risk Factors of Mortality in Patients with Posterior Reversible Encephalopathy Syndrome
CONCLUSIONS: Our results indicate that PRES could be considered as a sign of a very high-risk patient. We also demonstrated that heart failure and stroke were independent risk factors for death in patients with PRES; moreover, pregnancy was a protective factor.PMID:36419591 | PMC:PMC9678458 | DOI:10.1155/2022/9401661
Source: Behavioural Neurology - November 24, 2022 Category: Neurology Authors: Hong-Wei Cui Ru-Yi Lei Bo-Ai Zhang Source Type: research

Identification of magnetic resonance imaging features for the prediction of unrecognized atrial fibrillation in acute ischemic stroke
Conclusion Initial MRI at the time of stroke may be useful to predict which patients have cardioembolic stroke caused by unrecognized AF. Further studies are warranted to verify these findings and their application to high-risk patients.
Source: Frontiers in Neurology - September 13, 2022 Category: Neurology Source Type: research

Association Between Motor and Cognitive Performances in Elderly With Atrial Fibrillation: Strat-AF Study
Conclusions: In our cohort of elderly AF patients, a direct association between motor and cognitive functions consistently recurred using different evaluation of the performances, without an evident mediating role of cerebral lesions burden.
Source: Frontiers in Neurology - November 13, 2020 Category: Neurology Source Type: research

Effect of Remote Ischemic Conditioning in Patients With Takotsubo Syndrome After Acute Stroke: Study Protocol for a Randomized Controlled Trial
This study has been approved by the Medical Ethics Committee of Xuanwu Hospital, Capital Medical University ([2017] 072). The study findings will be presented at international conferences and published in a peer-reviewed journal.Trial registration: This study has been prospectively registered in the Chinese Clinical Trial Registry on September 10, 2018 (ChiCTR1800018290).
Source: Frontiers in Neurology - April 27, 2020 Category: Neurology Source Type: research

Potential Applications of Remote Limb Ischemic Conditioning for Chronic Cerebral Circulation Insufficiency
Conclusion Due to its long-term and often invisible course, CCCI has received less attention than acute cerebral ischemic stroke. However, without appropriate intervention, CCCI may lead to a variety of adverse events. Because the pathophysiological changes associated with CCCI are complex, pharmacological research in this area has been disappointing. Recent research suggests that RLIC, which is less invasive and more well-tolerated than drug treatment, can activate endogenous protective mechanisms during CCCI. In the present report, we reviewed studies related to CCCI (Table 1), as well as those related to stroke and sta...
Source: Frontiers in Neurology - May 2, 2019 Category: Neurology Source Type: research

Combination of Dexmedetomidine and Ketamine for Magnetic Resonance Imaging Sedation
Conclusions: The efficacy of DEX–KET sedation was comparable to that of midazolam for MRI examination. DEX–KET was related to shorter scan time and lower occurrence of complications compared to midazolam. Introduction Neurocritically ill patients often require brain magnetic resonance imaging (MRI) in addition to conventional neurological evaluations. Brain MRI can reveal structural lesions with a high sensitivity due to its excellent spatial resolution and enhanced soft tissue contrast (1–3). To acquire MRI images, patients' cooperation is imperative. However, keeping patients with ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Development of a cerebrovascular magnetic resonance imaging biomarker for cognitive aging
ObjectiveRecent availability of amyloid and tau positron emission tomography (PET) has provided us with a unique opportunity to measure the association of systemic vascular health with brain health after accounting for the impact of Alzheimer disease (AD) pathologies. We wanted to quantify early cerebrovascular health –related magnetic resonance imaging brain measures (structure, perfusion, microstructural integrity) and evaluate their utility as a biomarker for cerebrovascular health.MethodsWe used 2 independent samples (discovery, n  = 390; validation, n = 1,035) of individuals, aged ≥ 60 years, along the...
Source: Annals of Neurology - October 25, 2018 Category: Neurology Authors: Prashanthi Vemuri, Timothy G. Lesnick, Scott A. Przybelski, Jonathan Graff ‐Radford, Robert I. Reid, Val J. Lowe, Samantha M. Zuk, Matthew L. Senjem, Christopher G. Schwarz, Jeffrey L. Gunter, Kejal Kantarci, Mary M. Machulda, Michelle M. Mi Tags: Research Article Source Type: research

Age, vascular health, and Alzheimer disease biomarkers in an elderly sample
ObjectiveTo investigate the associations between age, vascular health, and Alzheimer disease (AD) imaging biomarkers in an elderly sample. MethodsWe identified 430 individuals along the cognitive continuum aged >60 years with amyloid positron emission tomography (PET), tau PET, and magnetic resonance imaging (MRI) scans from the population‐based Mayo Clinic Study of Aging. A subset of 329 individuals had fluorodeoxyglucose (FDG) PET. We ascertained presently existing cardiovascular and metabolic conditions (CMC) from health care records and used the summation of presence/absence of hypertension, hyperlipidemia, cardia...
Source: Annals of Neurology - October 26, 2017 Category: Neurology Authors: Prashanthi Vemuri, Timothy G. Lesnick, Scott A. Przybelski, David S. Knopman, Val J. Lowe, Jonathan Graff ‐Radford, Rosebud O. Roberts, Michelle M. Mielke, Mary M. Machulda, Ronald C. Petersen, Clifford R. Jack Tags: Research Article Source Type: research

Postpartum cardiomyopathy with cardioembolic stroke (p3.298)
Conclusions:Peripartum cardiomyopathy is a rare cause of stroke. Though seldom described, it should be considered in appropriate female patients presenting with neurological deficits. Definitive therapy with anticoagulation should be considered to prevent further complications.Disclosure: Dr. Kumbham has nothing to disclose. Dr. Sharma has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Masangkay has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Kumbham, P., Sharma, B., Patel, A., Masangkay, N. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Multiple Sclerosis Exacerbation Presenting as Stress Cardiomyopathy (P6.162)
Conclusions: Stress cardiomyopathy is increasingly suspected to be neurogenic in etiology. This case not only supports this theory, but also reports multiple sclerosis to be a potential cause of neurologic dysfunction leading to this cardiac phenomenon. In addition, it fortifies the theory that bilateral medullary lesions are required for many instances of autonomic dysfunction.Disclosure: Dr. Webb has nothing to disclose. Dr. Reyna has nothing to disclose. Dr. Blair has nothing to disclose. Dr. Foreman has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Webb, T., Reyna, T., Blair, R., Foreman, R. Tags: Multiple Sclerosis Symptoms and Comorbidities Source Type: research

Cardiovascular Biomarkers and Subclinical Brain Disease in the Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— NT-proBNP and hs-cTnT are independently associated with silent MRI-defined BI and WML, suggesting that cardiovascular biomarkers may be useful to identify individuals with subclinical cerebral injury.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Dadu, R. T., Fornage, M., Virani, S. S., Nambi, V., Hoogeveen, R. C., Boerwinkle, E., Alonso, A., Gottesman, R. F., Mosley, T. H., Ballantyne, C. M. Tags: Risk Factors, Brain Circulation and Metabolism, Cerebral Lacunes, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research