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Condition: Heart Failure
Therapy: Cardiac Resynchronization Therapy

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Total 117 results found since Jan 2013.

Prediction of long-term outcome of cardiac resynchronization therapy by acute pressure-volume loop measurements
Conclusion Invasive assessment of acute haemodynamics is a reliable tool to determine individual response to CRT. An acute increase in SW predicts long-term response to CRT with a higher accuracy than an acute increase in dP/dtmax, baseline QRS duration, and degree of LV mechanical dyssynchrony.
Source: European Journal of Heart Failure - February 20, 2013 Category: Cardiology Authors: de Roest, G. J., Allaart, C. P., Kleijn, S. A., Delnoy, P. P. H. M., Wu, L., Hendriks, M. L., Bronzwaer, J. G. F., van Rossum, A. C., de Cock, C. C. Tags: CRT Source Type: research

Abstract 227: Prescribing Warfarin at Discharge for Heart Failure Patients without Atrial Fibrillation Findings from the Get With The Guidelines-Heart Failure Registry Poster Session II
Conclusions: Approximately 1 in 10 HF patients without AF or other documented indications are prescribed warfarin at discharge, and prescription rates vary widely across hospitals. Further research is needed to understand why anticoagulation is prescribed to patients with HF in the absence of documented indications.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Eapen, Z., Grau-Sepulveda, M., Fonarow, G., Heidenreich, P., Peterson, E., Hernandez, A. Tags: Poster Session II Source Type: research

Effect of atrioventricular and ventriculoventricular delay optimization on clinical and echocardiographic outcomes of patients treated with cardiac resynchronization therapy: A meta-analysis
Conclusion: The current literature suggests that routine AV and/or VV delay optimization has a neutral effect on clinical and echocardiographic outcomes based on pooled data from randomized and nonrandomized studies. Standardization of patient selection and optimization timing and method may help to further define the role of CRT device optimization.
Source: American Heart Journal - May 2, 2013 Category: Cardiology Authors: Dominique Auger, Ulas Hoke, Jeroen J. Bax, Eric Boersma, Victoria Delgado Tags: Curriculum in Cardiology Source Type: research

CHADS2 and CHA2DS2-VASc scores to predict morbidity and mortality in heart failure patients candidates to cardiac resynchronization therapy
Conclusion In CRT-D patients, pre-implant CHA2DS2-VASc score is an independent predictor of major clinical events at 30-month follow-up.
Source: Europace - December 16, 2013 Category: Cardiology Authors: Paoletti Perini, A., Bartolini, S., Pieragnoli, P., Ricciardi, G., Perrotta, L., Valleggi, A., Vergaro, G., Michelotti, F., Boggian, G., Sassone, B., Mascioli, G., Emdin, M., Padeletti, L. Tags: Pacing and resynchronization therapy Source Type: research

Scar tissue–guided left ventricular lead placement for cardiac resynchronization therapy in patients with ischemic cardiomyopathy: An acute pressure-volume loop study
Background: Response to cardiac resynchronization therapy (CRT) is hampered by the extent and location of left ventricular (LV) scar tissue. It is commonly advised to avoid scar tissue while placing the LV lead. However, whether individual patients benefit from this strategy remains unclear.Methods: Thirty-two CRT candidates with ischemic cardiomyopathy were enrolled from 2 successive clinical trials (TBS and E-pot study). Magnetic resonance imaging with late contrast enhancement was performed to assess location, degree and transmurality of LV scar tissue. Patients underwent invasive pressure-volume loop measurements to as...
Source: American Heart Journal - January 16, 2014 Category: Cardiology Authors: Gerben Jan de Roest, LiNa Wu, Carel C. de Cock, Matthijs L. Hendriks, Peter Paul H.M. Delnoy, Albert C. van Rossum, Cornelis P. Allaart Tags: Heart Failure Source Type: research

Cardiac Responses to Left Ventricular Pacing in Hearts with Normal Electrical Conduction: Beneficial Effect of Improved Filling is Counteracted by Dyssynchrony.
In conclusion, pacing of the LV lateral wall increased LVEDV by displacing the septum rightwards, suggesting a mechanism for a favorable effect of CRT in narrow QRS. The pacing, however, induced dyssynchrony and therefore reduced LV systolic function. These observations suggest that detrimental effects should be considered when applying CRT in patients with narrow QRS. PMID: 24906920 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - June 6, 2014 Category: Physiology Authors: Boe E, Russell K, Remme EW, Gjesdal O, Smiseth OA, Skulstad H Tags: Am J Physiol Heart Circ Physiol Source Type: research

Complex cardiac pacing in the setting of a district general hospital: procedural success and complications
Conclusions In the presence of necessary clinical expertise, complex cardiac devices can be implanted successfully and with a high degree of safety in the setting of a district general hospital.
Source: Heart Asia - June 24, 2014 Category: Cardiology Authors: Rahbi, H., El-din, M., Salloum, M., Shaukat, N., Farooq, M. Tags: Original research Source Type: research

Cardiac responses to left ventricular pacing in hearts with normal electrical conduction: beneficial effect of improved filling is counteracted by dyssynchrony
In conclusion, pacing of the LV lateral wall increased LVEDV by displacing the septum rightward, suggesting a mechanism for a favorable effect of CRT in narrow QRS. The pacing, however, induced dyssynchrony and therefore reduced LV systolic function. These observations suggest that detrimental effects should be considered when applying CRT in patients with narrow QRS.
Source: AJP: Heart and Circulatory Physiology - August 1, 2014 Category: Cardiology Authors: Boe, E., Russell, K., Remme, E. W., Gjesdal, O., Smiseth, O. A., Skulstad, H. Tags: MUSCLE MECHANICS AND VENTRICULAR FUNCTION Source Type: research

Cardiac Resynchronization Therapy Acutely Improves Ventricular‐Arterial Coupling by Reducing the Arterial Load: Assessment by Pressure–Volume Loops
ConclusionOur data indicate that switching CRT on induces an immediate reduction in arterial load, conceivably as a consequence of restored autonomic balance.
Source: Pacing and Clinical Electrophysiology : PACE - January 28, 2015 Category: Cardiology Authors: PAOLO PIERAGNOLI, GIOVANNI BATTISTA PEREGO, GIUSEPPE RICCIARDI, STEFANIA SACCHI, MARGHERITA PADELETTI, ANTONIO MICHELUCCI, SERGIO VALSECCHI, LUIGI PADELETTI Tags: ORIGINAL ARTICLE Source Type: research

Biotronik launches Itrevia MRI-safe quad CRT-D in Japan
Biotronik said today that it launched its Itrevia MRI-safe quad cardiac resynchronization therapy defibrillator in Japan, part of a Japanese rollout of new devices for 2015. The device is equipped with home monitoring connectivity, as well as compatibility with up to 1.5 tesla MRI machines, the German medical device giant said. “As a producer of superior medical technologies, it is imperative for us to have a presence in the world’s leading technologies market. It also makes sense that the world’s biggest producer of ProMRI technology should have a strong presence in the country where MRI scanning is the...
Source: Mass Device - July 2, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Cardiac Assist Devices Cardiac Implants Cardiovascular Surgical Biotronik Source Type: news

Echocardiography and cardiac resynchronization therapy
Publication date: Available online 12 September 2015 Source:Cor et Vasa Author(s): Josef Marek, Jana Gandalovičová, Eva Kejřová, Miroslav Pšenička, Aleš Linhart, Tomáš Paleček Cardiac resynchronization therapy (CRT) is an effective therapeutic option in patients with congestive heart failure, left ventricular ejection fraction≤35%, and a widened QRS complex. However, a significant proportion of individuals do not respond to CRT favorably. Understandably, a large number of studies have addressed various techniques to improve patient selection for CRT and to improve responder rate in patients with CRT dev...
Source: Cor et Vasa - September 12, 2015 Category: Cardiology Source Type: research

Letter by Cacko, et al Regarding Article, "Improvement of Cardiac Function by Increasing Stimulus Strength During Left Ventricular Pacing in Cardiac Resynchronization Therapy".
Authors: Cacko A, Michalak M, Główczyńska R, Kochanowski J, Grabowski M Abstract Dear Editor,We have read with great interest the article discussing an improvement of cardiac function by increasing stimulus strength during left ventricular pacing in cardiac resynchronization therapy (CRT) by Ishibashi, et al.(1)) The authors investigated whether increasing stimulus strength of left ventricle (LV) pacing improves LV mechanical dyssynchrony and cardiac function in patients treated with CRT. According to their observation higher stimulus strength may result in statistically significant decreases in QRS duration, se...
Source: International Heart Journal - September 16, 2015 Category: Cardiology Tags: Int Heart J Source Type: research

Dynamic Changes in High‐Sensitivity Cardiac Troponin I Are Associated with Dynamic Changes in Sum Absolute QRST Integral on Surface Electrocardiogram in Acute Decompensated Heart Failure
ConclusionPatient‐specific time‐varying changes in the surface ECG scalar measure of global electrical heterogeneity, as measured by SAI QRST, and in myocardial injury as measured by hsTnI, are independently and directly associated with each other, likely reflecting a common underlying mechanism.
Source: Annals of Noninvasive Electrocardiology - June 5, 2016 Category: Cardiology Authors: Larisa G. Tereshchenko, Albert Feeny, Erica Shelton, Thomas Metkus, Andrew Stolbach, Ernest Mavunga, Shannon Putman, Frederick K. Korley Tags: Original Article Source Type: research

Mortality After Atrioventricular Nodal Radiofrequency Catheter Ablation With Permanent Ventricular Pacing in Atrial Fibrillation: Outcomes From a Controlled Nonrandomized Study Original Article
Conclusions— In sick AF patients with multiple comorbidities, AVNA with permanent ventricular pacing for rate control seems safe during follow-up and may be associated with lower mortality.
Source: Circulation: Arrhythmia and Electrophysiology - June 29, 2016 Category: Cardiology Authors: Garcia, B., Clementy, N., Benhenda, N., Pierre, B., Babuty, D., Olshansky, B., Fauchier, L. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Atrial Fibrillation Original Article Source Type: research

Dynamic Changes in High ‐Sensitivity Cardiac Troponin I Are Associated with Dynamic Changes in Sum Absolute QRST Integral on Surface Electrocardiogram in Acute Decompensated Heart Failure
ConclusionPatient‐specific time‐varying changes in the surface ECG scalar measure of global electrical heterogeneity, as measured by SAI QRST, and in myocardial injury as measured by hsTnI, are independently and directly associated with each other, likely reflecting a common underlying mechanism.
Source: Annals of Noninvasive Electrocardiology - June 5, 2016 Category: Cardiology Authors: Larisa G. Tereshchenko, Albert Feeny, Erica Shelton, Thomas Metkus, Andrew Stolbach, Ernest Mavunga, Shannon Putman, Frederick K. Korley Tags: Original Article Source Type: research