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Stroke in supplementary motor area mimicking functional disorder: a case report
We report a 59-year-old man with previous history for myocardial infarction, referred to emergency room with an acute dense right-side hemiplegia, positive Hoover sign, asymmetrical Babinski responses and intermittent ability to move his arm in some specific reflex actions despite plegia. Since brain computed tomography scan was unremarkable we could not be sure whether his symptoms were organic or functional until a diffusion weighted imaging of magnetic resonance imaging elucidated the situation. To our knowledge, there is only one case report in the literature prior to ours, presenting a supplementary motor area stroke ...
Source: Journal of Neurology - September 28, 2019 Category: Neurology Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Visual field defect after ischemic stroke —impact on mortality
ConclusionsHaving a visual field defect after ischemic stroke is independently associated with increased mortality. This should be addressed when selecting candidates for thrombolysis and in the rehabilitation process.
Source: Acta Neurologica Scandinavica - November 17, 2017 Category: Neurology Authors: K. M. Sand, H. N æss, L. Thomassen, J. M. Hoff Tags: ORIGINAL ARTICLE Source Type: research

Accelerated atherosclerosis in ANCA ‐associated vasculitis
ConclusionsOur study adds weight to the presence of increased atherosclerosis in AAV‐patients. The association observed between CIMT and PI‐ICA with small vessel cerebral disease, points the possible association of easy to use carotid US in predicting microvascular brain injury.
Source: Acta Neurologica Scandinavica - June 13, 2017 Category: Neurology Authors: I. Gonz ález‐Suárez, J. J. Ríos‐Blanco, J. Arpa Tags: ORIGINAL ARTICLE Source Type: research

Lipid Changes Around the Final Menstrual Period Predict Carotid Subclinical Disease in Postmenopausal Women Clinical Sciences
Conclusions—Changes in lipids as women approach the FMP provide useful clinical information for understanding postmenopausal carotid indices.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Karen A. Matthews, Samar R. El Khoudary, Maria M. Brooks, Carol A. Derby, Sioban D. Harlow, Emma J.M. Barinas–Mitchell, Rebecca C. Thurston Tags: Epidemiology, Women, Atherosclerosis, Coronary Artery Disease Original Contributions Source Type: research

Dynamic Magnetic Resonance Angiography Provides Collateral Circulation and Hemodynamic Information in Acute Ischemic Stroke Brief Reports
Conclusions— As a fast, direct, feasible, noninvasive, and reliable method to assess site of occlusion, collateral circulation and hemodynamic alterations, dMRA provides profound insights in acute stroke.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Hernandez-Perez, M., Puig, J., Blasco, G., Perez de la Ossa, N., Dorado, L., Davalos, A., Munuera, J. Tags: Imaging, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke
Conclusions: Our data identify a genetic contribution to inflammatory and hemostatic biomarkers in a stroke population. Additionally, our results suggest shared genetic contributions to circulating CRP levels measured poststroke and risk for incident and recurrent ischemic stroke. These data broaden our understanding of genetic contributors to biomarker variation and ischemic stroke risk, which should be useful in clinical risk evaluation.
Source: Neurology - January 25, 2016 Category: Neurology Authors: Williams, S. R., Hsu, F.-C., Keene, K. L., Chen, W.-M., Nelson, S., Southerland, A. M., Madden, E. B., Coull, B., Gogarten, S. M., Furie, K. L., Dzhivhuho, G., Rowles, J. L., Mehndiratta, P., Malik, R., Dupuis, J., Lin, H., Seshadri, S., Rich, S. S., Sale Tags: All Cerebrovascular disease/Stroke, Case control studies, Risk factors in epidemiology, All Genetics, Association studies in genetics ARTICLE Source Type: research

The Role of FEIBA in Reversing Novel Oral Anticoagulants in Intracerebral Hemorrhage
Conclusion In this small case series, reversal of NOAC with FEIBA was not associated with ICH expansion or any thrombotic or hemorrhagic complications.
Source: Neurocritical Care - November 6, 2015 Category: Neurology Source Type: research

Effects of candesartan in acute stroke on vascular events during long‐term follow‐up: results from the Scandinavian Candesartan Acute Stroke Trial (SCAST)
ConclusionsTreatment with candesartan in the acute phase of stroke was not associated with clear long‐term clinical benefits. This result supports the conclusion from trials with short‐term follow‐up, that blood pressure lowering treatment with candesartan should not be given routinely to patients with acute stroke and raised blood pressure.
Source: International Journal of Stroke - March 23, 2015 Category: Neurology Authors: Astrid G. Hornslien, Else C. Sandset, Jannicke Igland, Andreas Terént, Gudrun Boysen, Philip M. W. Bath, Gordon D. Murray, Eivind Berge Tags: Research Source Type: research

Effects of Blood Pressure-Lowering Treatment in Different Subtypes of Acute Ischemic Stroke Brief Reports
Conclusions— The results suggest that the effect of blood pressure–lowering treatment with candesartan may differ according to different types of acute ischemic stroke, but this needs to be confirmed in future trials. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Sandset, E. C., Jusufovic, M., Sandset, P. M., Bath, P. M. W., Berge, E., on behalf of the SCAST Study Group Tags: Cerebrovascular disease/stroke, Clinical Studies Brief Reports Source Type: research

Effects of blood pressure lowering in patients with acute ischemic stroke and carotid artery stenosis
ConclusionsThere is no clear evidence that the effect of candesartan is qualitatively different in patients with carotid artery stenosis, but there are signals that patients with severe stenosis are at particularly high risk of stroke progression and poor functional outcome.
Source: International Journal of Stroke - December 3, 2014 Category: Neurology Authors: Mirza Jusufovic, Else Charlotte Sandset, Philip M. W. Bath, Björn W. Karlson, Eivind Berge, Tags: Research Source Type: research

Blood Pressure-Lowering Treatment With Candesartan in Patients With Acute Hemorrhagic Stroke Brief Reports
Conclusions— There was no evidence that blood pressure–lowering treatment with candesartan is beneficial during the first week of hemorrhagic stroke. Instead, there were signs that such treatment may be harmful, but this needs to be verified in larger studies. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Jusufovic, M., Sandset, E. C., Bath, P. M. W., Berge, E., on behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Brief Reports Source Type: research

Prediction of myocardial infarction in patients with transient ischaemic attack
ConclusionAccording to our results, discrimination was poor for all previous risk prediction models evaluated. Variables such as previous CHD, male sex, DWI and ECG abnormalities should be considered in new prediction models.
Source: Acta Neurologica Scandinavica - October 10, 2014 Category: Neurology Authors: M. B. Vilanova, G. Mauri‐Capdevila, J. Sanahuja, A. Quilez, G. Piñol‐Ripoll, R. Begué, M. I. Gil, M. C. Codina‐Barios, I. Benabdelhak, F. Purroy Tags: Original Article Source Type: research

Arterial stiffness as a risk factor for cerebral aneurysm
ConclusionsThe baPWV was associated with intracranial saccular aneurysms even after adjustment of hypertension and smoking. Assessment of the baPWV may aid the evaluation of the intracranial saccular aneurysm and the development of strategies for screening patients with intracranial saccular aneurysms.
Source: Acta Neurologica Scandinavica - September 1, 2014 Category: Neurology Authors: H. Matsukawa, M. Shinoda, M. Fujii, A. Uemura, O. Takahashi, Y. Niimi Tags: Original Article Source Type: research

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