Filtered By:
Specialty: Cardiology
Condition: Heart Attack
This page shows you your search results in order of date. This is page number 8.
Order by Relevance | Date
Total 6275 results found since Jan 2013.
Anti-inflammatory therapies were associated with reduced risk of myocardial infarction in patients with established cardiovascular disease or high cardiovascular risks: A systematic review and meta-analysis of randomized controlled trials
CONCLUSIONS: Anti-inflammatory therapies, especially those targeting the central IL-6 signaling pathway, may serve as promising treating strategies to ameliorate the risk of MI. IL-1 inhibitor and colchicine were associated with decreased risks of heart failure and stroke, respectively. MI risk reduction by anti-inflammatory therapies seemed to be more prominent in older patients with long follow-up duration.PMID:37527612 | DOI:10.1016/j.atherosclerosis.2023.06.972
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: Zonglin Li Chu Lin Xiaoling Cai Suiyuan Hu Fang Lv Wenjia Yang Xingyun Zhu Linong Ji Source Type: research
Therapeutic targeting of the LncRNA IMSET suppresses inflammation and atherosclerotic plaque progression
Background and Aims: Perpetual monocyte/macrophage recruitment and subsequent foam cell formation characterises advanced atherosclerotic plaques, especially lesions precipitating myocardial infarction and stroke. Recent advances have illuminated macrophage diversity within atherosclerotic plaques, with select populations attributed a deleterious role. Accordingly, novel targets within specific macrophage subsets may yield therapeutic potential.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: K. Di Gregoli, A. Bond, S. Smith, S. George, J. Johnson Source Type: research
Differences in the peripheral immune cell landscape in atherosclerosis – Insights from the LURIC single cell RNA-sequencing study (LURNA)
Background and Aims: Atherosclerosis and its clinical sequelae, myocardial infarction and stroke, represent the main causes of death worldwide. Although preclinical evidence has suggested the existence of a sustained inflammatory and immune response driving disease and complications, the extend of cellular alterations in human atherosclerosis remains enigmatic. Here, we employ single cell RNA-sequencing (scRNA-seq) on peripheral blood mononucleated cells in a well-defined cardiovascular risk cohort from the the LURIC trial to define changes in the immune cell landscape in atherosclerotic patients.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: H. Horstmann, N. Anto-Michel, X. Sheng, S. Hansen, D. Westermann, W. M ärz, A. Zirlik, D. Wolf Source Type: research
Plasma TSH and cardiovascular risk in the general population
Background and Aims: The association between thyroid stimulating hormone (TSH) and cardiovascular disease has mainly been determined using clinical categories of disease. We tested the hypothesis that TSH on a continuous scale is associated with risk of atrial fibrillation (AF), myocardial infarction (MI), stroke, heart failure (HF), aortic valve stenosis (AVS), and major adverse cardiovascular events (MACE) and whether these associations are likely to be causal.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: N. Dalila, R. Frikke-Schmidt, B. Nordestgaard, A. Tybjaerg-Hansen Source Type: research
Inertial cavitation-mediated catheter- based Q-switched Nd: YAG laser therapy in combination with extracorporeal electrohydraulic low- level focused shock wave therapy for thrombolysis of embolic artery
Background and Aims: A plaque may rupture with high risk of subsequent thrombus mediated acute clinical events such as myocardial infarction and stroke. The aim of this study was to generate a rabbit model of carotid artery thromboembolic occlusion and the subsequent investigating the feasibility of catheter- based Q-switched Nd: YAG laser therapy accompanied by simultaneously extracorporeal shock wave therapy in this model.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: H. Mehrad Source Type: research
Elevated remnant cholesterol in atherosclerotic cardiovascular disease in diabetes: A population-based prospective cohort study
Background and Aims: Elevated remnant cholesterol is causally associated with increased risk of atherosclerotic cardiovascular disease (ASCVD) in the general population. We tested the hypothesis that elevated remnant cholesterol is associated with increased risk of peripheral artery disease, myocardial infarction, ischemic stroke, and any ASCVD in individuals with diabetes.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: B. Wadstr öm, K. Pedersen, A. Wulff, B. Nordestgaard Source Type: research
Efficacy of Percutaneous Coronary Intervention With Synergy Stents in Patients Aged ≥75 Years: 1-Year Clinical Outcomes from the Synergy Elderly Registry
This study investigated the 12-month clinical outcomes of older patients who underwent percutaneous coronary intervention with new-generation drug-eluting stents according to ischemic risks. This prospective multicenter study targeted patients aged ≥75 years who underwent S-EES implantation. The primary and secondary end points included 12-month device-oriented composite end point (DOCE) (cardiovascular death, target vessel myocardial infarction, or target lesion revascularization) and major adverse cardiac and cerebrovascular events (MACCE s; all-cause death, myocardial infarction, target vessel revascularization, sten...
Source: The American Journal of Cardiology - August 1, 2023 Category: Cardiology Authors: Jong-Il Park, Seung-Jun Lee, Young-Joon Hong, Sang-Yong Yoo, Yong-Sung Seo, Eui Im, Jong-Kwan Park, Jin-Bae Lee, Yong-Joon Lee, Sung-Jin Hong, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Byeong-Keuk Kim Source Type: research
BMP-7 attenuates TLR4-NLRP3 inflammasome mediated pyroptosis in vascular smooth muscle cells in atherosclerotic plaques
Background and Aims: Atherosclerosis (ATH) is an inflammation-mediated disease in which cell death underlies the formation of lesions along the intima layer of vascular walls resulting in vessel narrowing, decreased blood-flow, and increased risk of lesion rupture leading to myocardial infarction and stroke. The current study was undertaken to investigate whether inflammation in ATH can induce pyroptosis in vascular smooth muscle cells (vSMC ’s). To study this, we established disturbed flow-induced hemodynamic injury to the vascular wall using our partial left carotid artery ligation (PLCA) model.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: D. Singla, C. Narasimhulu Source Type: research
The attenuated metabolic suppression and elevated mTOR levels in replicatively aged fibroblasts may contribute to atherosclerosis in Hutchinson Gilford Progeria
Background and Aims: Hutchinson Gilford Progeria (HGP) is characterized by accelerated aging and premature death caused by myocardial infarction or stroke. Enhanced metabolism and proliferation may accelerate senescence entry and atherogenesis. We therefore related cellular proliferation and exogenous stress to mTOR signaling in four control and four HGP fibroblast cell lines.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: J. Mensch, K. J äger, M. Grimmig, A. Hartmann, M. Walter Source Type: research
Impact of Atherothrombotic risk stratification in patients with heavily calcified lesions following rotational Atherectomy
CONCLUSIONS: Atherothrombotic risk stratification using TRS 2°P was useful in identifying high-risk patients with heavily calcified lesions following RA.PMID:37524300 | DOI:10.1016/j.jjcc.2023.07.013
Source: Journal of Cardiology - July 31, 2023 Category: Cardiology Authors: Toru Yoshizaki Takamitsu Nakamura Takeo Horikoshi Yosuke Watanabe Tsuyoshi Kobayashi Yukio Saito Jun-Ei Obata Takao Sawanobori Hajime Takano Ken Umetani Tetsuya Asakawa Akira Sato Source Type: research
Association between coffee or tea consumption and cardiovascular outcomes in patients with stable coronary artery disease: Analysis from the CLARIFY registry
CONCLUSIONS: In outpatients with stable coronary artery disease, there was no association between coffee or tea consumption and ischaemic outcomes or all-cause mortality.PMID:37524628 | DOI:10.1016/j.acvd.2023.05.007
Source: Archives of Cardiovascular Diseases - July 31, 2023 Category: Cardiology Authors: Jeremie Abtan Gregory Ducrocq Yedid Elbez Roberto Ferrari Ian Ford Kim M Fox Jean-Claude Tardif Michal Tendera Nicolas Danchin Alexander Parkhomenko Christopher M Reid P Gabriel Steg Source Type: research
Impact of Atherothrombotic risk stratification in patients with heavily calcified lesions following rotational Atherectomy
CONCLUSIONS: Atherothrombotic risk stratification using TRS 2°P was useful in identifying high-risk patients with heavily calcified lesions following RA.PMID:37524300 | DOI:10.1016/j.jjcc.2023.07.013
Source: Journal of Cardiology - July 31, 2023 Category: Cardiology Authors: Toru Yoshizaki Takamitsu Nakamura Takeo Horikoshi Yosuke Watanabe Tsuyoshi Kobayashi Yukio Saito Jun-Ei Obata Takao Sawanobori Hajime Takano Ken Umetani Tetsuya Asakawa Akira Sato Source Type: research
