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Johnson & Johnson Single-Shot COVID-19 Vaccine Phase 3 Data Published in New England Journal of Medicine
NEW BRUNSWICK, N.J., April 21, 2021 – Johnson & Johnson (the Company) today announced publication in the New England Journal of Medicine of primary data from the Phase 3 ENSEMBLE clinical trial for its single-dose COVID-19 vaccine, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen). The publication of the primary analysis follows the topline efficacy and safety data announced in January, showing the trial met all primary and key secondary endpoints, and found that the Johnson & Johnson single-dose COVID-19 vaccine prevented hospitalization and death across all study participants ...
Source: Johnson and Johnson - April 21, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Emergency Considerations in COVID-19 Vaccine Administration
Conclusion The joint response of science and medicine to develop safe and effective COVID-19 vaccines has been brisk and productive. Distribution efforts will now be the next step in limiting the breadth of this pandemic. EMS agencies will play a key role in some areas in the administration of vaccinations for their communities. The authors suggest that to better clarify the side effects of the COVID-19 vaccines, EMS systems must maintain a log of the type and incidence of adverse events following vaccine administration, EMS responses to the adverse events, as well as those patients’ outcomes from this management. ...
Source: JEMS Patient Care - December 16, 2020 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus Exclusives EMS EMT Paramedic Source Type: news

The influence of allergic rhinoconjunctivitis on migraine disability in children
Conclusions Current allergic rhinoconjunctivitis is related to enhanced disability caused by headache in childhood migraine.RESUMO A enxaqueca é condição comum na população pediátrica e causa significativo impacto na qualidade de vida. Doenças atópicas estão entre as principais morbidades associadas. Objetivo Teorizamos que a rinite alérgica possa agravar a enxaqueca na população pediátrica. Métodos Este estudo transversa l avaliou consecutivamente 90 pacientes pediátricos (46 crianças de 6 a 12 anos; 44 adolescentes até 18 anos) que procuraram assistência por enxaqueca em clínica neurológica de Passo F...
Source: Arquivos de Neuro-Psiquiatria - July 16, 2019 Category: Neurology Source Type: research

Drought in the Semiarid Region of Brazil: Exposure, Vulnerabilities and Health Impacts from the Perspectives of Local Actors
Conclusion The results obtained from this research shows, in general, the fragility in the social and political infrastructure necessary to improve the living conditions of populations, particularly those that depend on family agriculture in drought prone areas. The conditions of social, economic and environmental vulnerabilities presented in the region can be amplified by the drought process, and can aggravate the impacts resulting drought events, thus disadvantaging the population of this region, as shown in the Fig. 1. The general perception of the interviewees of the health sector shows an agreement with what is found...
Source: PLOS Currents Disasters - October 29, 2018 Category: International Medicine & Public Health Authors: Aderita Sena Source Type: research

Clinical and Laboratory Profile of Zika and Dengue Infected Patients: Lessons Learned From the Co-circulation of Dengue, Zika and Chikungunya in Brazil
In conclusion, our data characterized the occurrence of an ongoing triple epidemic caused by DENV, ZIKV and CHIKV in Campo Grande, MS, Brazil. Importantly, the knowledge about dengue or zika severity in co-infected individuals is still unknown, however we provided here, new contributions related to the clinical presentations and laboratorial parameters during DENV and ZIKV infections, in an endemic scenario. Author Contributions Performed the experiments: ELA, TMALS, RVC, FBS. Contribute reagents material analyses tools: ELA, FBS, RVC. Wrote the paper: ELA. RVC. Participate in patient enrollment and records: ELA, RVC, TMA...
Source: PLOS Currents Outbreaks - February 15, 2018 Category: Epidemiology Authors: Elzinandes Leal de Azeredo Source Type: research