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Total 6645 results found since Jan 2013.

Clinical predictors of wheeze trajectories and associations with allergy in Asian children
CONCLUSION: The timing of viral infection occurrence may determine the type of wheeze trajectory development in children. Children with family history of allergy and viral infections in early life may be predisposed to persistent wheeze development and the associated comorbidities early allergic sensitization and eczema.PMID:37419414 | DOI:10.1016/j.anai.2023.06.024
Source: Annals of Allergy, Asthma and Immunology - July 7, 2023 Category: Allergy & Immunology Authors: Hui Xing Lau Zhaojin Chen Hugo Van Bever Elizabeth Huiwen Tham Yiong Huak Chan Qai Ven Yep Anne Eng Neo Goh Oon Hoe Teoh Kok Hian Tan Fabian Kok Peng Yap Keith M Godfrey Johan G Eriksson Yap Seng Chong Bee Wah Lee Lynette Pei-Chi Shek Evelyn Xiu Ling Loo Source Type: research

Climate Change and Food Allergy
The role of environmental factors including climate change and consequent influences of air pollution on food allergy remains less explored compared with impacts on allergic rhinitis and asthma. In this review, we discuss the epithelial barrier hypothesis as a proposed mechanism of food allergy development that may be relevant in this context. We also discuss existing studies that provide insight into the intricate relationship between food allergy and climate-related environmental factors.
Source: Immunology and Allergy Clinics of North America - August 7, 2023 Category: Allergy & Immunology Authors: Ashley Sang Eun Lee, Nicole Ramsey Source Type: research

Therapeutic equivalence of triamcinolone acetonide hydrofluoroalkane and chlorofluorocarbon nasal inhalers in patients with seasonal allergic rhinitis.
CONCLUSION: In conclusion, a new formulation of TAA with a HFA propellant was found to be effective in the treatment of SAR and comparable with the previously available TAA CFC formulation. There was a dose response to TAA, with doses as low as 7 micrograms per nostril once daily producing statistically significant improvement in rhinitis symptoms. PMID: 23562198 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - March 1, 2013 Category: ENT & OMF Authors: Schenkel E, Newman KB Tags: Am J Rhinol Allergy Source Type: research

Can patients with common variable immunodeficiency have allergic rhinitis?
CONCLUSION: In CVID patients, chronic rhinitis may be allergic, because many have personal and family histories suggestive of atopy. However, in this study, allergy was confirmed by specific IgE detection in only 5.6% of cases. CVID patients with a history suggestive of AR commonly present negative results on traditional testing, so additional experiments may be necessary. One suggestion for the investigation of AR in CVID patients would be nasal provocation with the most prevalent allergens. PMID: 23562193 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - March 1, 2013 Category: ENT & OMF Authors: Agondi RC, Barros MT, Kokron CM, Cohon A, Oliveira AK, Kalil J, Giavina-Bianchi P Tags: Am J Rhinol Allergy Source Type: research

Chapter 17: Immunomodulation of allergic sinonasal disease.
Abstract IgE hypersensitivity is important to the pathogenesis of allergic diseases and the development and persistence of airway inflammation. Allergic immunomodulation encompasses various therapies that attempt to suppress or modify the immune mechanisms responsible for IgE-mediated disease. These include allergy immunotherapy (AIT) in the forms of subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT), as well as the emergence of biological agents, such as anti-IgE, for allergic respiratory disease. Clinical evidence strongly supports the efficacy and safety of AIT for the treatment of allergic r...
Source: American Journal of Rhinology and Allergy - May 1, 2013 Category: ENT & OMF Authors: Settipane RA, Peters AT, Borish L Tags: Am J Rhinol Allergy Source Type: research

Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status
Recently, our research team found a strong and significant association between loss-of-function (LOF) mutations in filaggrin (FLG), a gene that encodes a skin barrier protein, in European and Canadian individuals with peanut allergy (PA). These mutations result in a barrier defect and have been associated with atopic dermatitis, asthma, and allergic rhinitis. This finding represents the strongest genetic risk factor found to date for PA, a highly heritable disease, with an estimated odds ratio (OR) between 1.9 (Canadian) and 5.3 (English, Dutch, and Irish combined). Because there is no uniformly accepted definition of PA s...
Source: Journal of Allergy and Clinical Immunology - May 20, 2013 Category: Allergy & Immunology Authors: Yuka Asai, Celia Greenwood, Peter R. Hull, Reza Alizadehfar, Moshe Ben-Shoshan, Sara J. Brown, Linda Campbell, Deborah L. Michel, Johanne Bussières, François Rousseau, T. Mary Fujiwara, Kenneth Morgan, Alan D. Irvine, W.H. Irwin McLean, Ann Clarke Tags: Letters to the Editor Source Type: research

Randomized double-blind placebo-controlled crossover study of efficacy of pollen blocker cream for perennial allergic rhinitis.
CONCLUSION: The pollen blocker was significantly more effective than the placebo in relieving allergy symptoms and improving life quality of PAR in 30 Chinese people. PMID: 23883812 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - July 1, 2013 Category: ENT & OMF Authors: Li Y, Wang D, Liu Q, Liu J Tags: Am J Rhinol Allergy Source Type: research

Comparison of the nasal release of IL-4, IL-10, IL-17, CCL13/MCP-4, and CCL26/eotaxin-3 in allergic rhinitis during season and after allergen challenge.
CONCLUSION: Nasal IL-17, MCP-4, and, possibly, eotaxin-3 may aggravate and IL-10 may alleviate nasal mucosal allergy. PMID: 23883806 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - July 1, 2013 Category: ENT & OMF Authors: Baumann R, Rabaszowski M, Stenin I, Tilgner L, Scheckenbach K, Wiltfang J, Schipper J, Chaker A, Wagenmann M Tags: Am J Rhinol Allergy Source Type: research

Paediatric rhinitis: position paper of the European Academy of Allergy and Clinical Immunology
Abstract Rhinitis is a common problem in childhood and adolescence and impacts negatively on physical, social and psychological well‐being. This position paper, prepared by the European Academy of Allergy and Clinical Immunology Taskforce on Rhinitis in Children, aims to provide evidence‐based recommendations for the diagnosis and therapy of paediatric rhinitis. Rhinitis is characterized by at least two nasal symptoms: rhinorrhoea, blockage, sneezing or itching. It is classified as allergic rhinitis, infectious rhinitis and nonallergic, noninfectious rhinitis. Similar symptoms may occur with other conditions such as ad...
Source: Allergy - July 1, 2013 Category: Allergy & Immunology Authors: G. Roberts, M. Xatzipsalti, L. M. Borrego, A. Custovic, S. Halken, P. W. Hellings, N. G. Papadopoulos, G. Rotiroti, G. Scadding, F. Timmermans, E. Valovirta Tags: Position Paper Source Type: research

Wheeze phenotypes in young children have different courses during the preschool period.
CONCLUSION: These results show that remission is most frequently observed in mild EVW and that no remission is observed in atopic MTW. PMID: 24054360 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - September 25, 2013 Category: Allergy & Immunology Authors: Just J, Saint-Pierre P, Gouvis-Echraghi R, Boutin B, Panayotopoulos V, Chebahi N, Ousidhoum-Zidi A, Khau CA Tags: Ann Allergy Asthma Immunol Source Type: research

Cytological changes in nasal secretions accompanying delayed nasal response to allergen challenge.
CONCLUSION: The DYNR is associated with cytological profiles in the NS different from those observed during the INR or LNR. The significant count changes of neutrophils, monocytes, lymphocytes, epithelial and goblet cells in NSs, and increased IFN-γ but not of IL-4 concentrations in the NLF, suggest a possible involvement of the cell-mediated hypersensitivity in the DYNR. These results also emphasize the diagnostic value of NPTs combined with cytological examination of the NSs in patients with nasal allergy. PMID: 24119599 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - September 1, 2013 Category: ENT & OMF Authors: Pelikan Z Tags: Am J Rhinol Allergy Source Type: research

Epidemiology of IgE-dependent allergic diseases in elderly patients in Poland.
CONCLUSION: This study confirms the high prevalence of allergic rhinitis and BA in elderly Polish patients. These findings are comparable with those involving groups of younger individuals with allergies. PMID: 24119595 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - September 1, 2013 Category: ENT & OMF Authors: Bozek A, Jarzab J Tags: Am J Rhinol Allergy Source Type: research

Characterizing rhinitis subtypes.
CONCLUSION: Other cellular, cytokine, genetic, and physiological markers have thus far been proven to be less useful. Ultimately, treatment response to medications will be most effective when they are individualized to the patient's diagnosis. PMID: 24274219 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - November 1, 2013 Category: ENT & OMF Authors: Bernstein JA Tags: Am J Rhinol Allergy Source Type: research