Filtered By:
Condition: Bipolar
Drug: Lithium
This page shows you your search results in order of date.
Order by Relevance | Date
Total 724 results found since Jan 2013.
Chronic Lithium Treatment Alters NMDA and AMPA Receptor Synaptic Availability and Dendritic Spine Organization in the Rat Hippocampus
CONCLUSION: Our findings highlight a previously unknown cohesive picture of the glutamatergic implications of LiCl action that persist long after the end of its administration, revealing for the first time a profound and persistent reorganization of the glutamatergic postsynaptic density receptor composition and structure.PMID:37711124 | DOI:10.2174/1570159X21666230913144420
Source: Current Neuropharmacology - September 15, 2023 Category: Drugs & Pharmacology Authors: Lucia Caffino Giorgia Targa Anne Stephanie Mallien Francesca Mottarlini Beatrice Rizzi Judith R Homberg Peter Gass Fabio Fumagalli Source Type: research
Preliminary results from the Australian Genetics of Bipolar Disorder Study: A nation-wide cohort
CONCLUSION: Our findings highlight the high rate of comorbidities and adverse drug reactions among adults living with bipolar disorder in the general Australian population. Future genomic analyses focus on identifying genetic variants influencing pharmacotherapy treatment response and side effects.PMID:37655588 | DOI:10.1177/00048674231195571
Source: The Australian and New Zealand Journal of Psychiatry - September 1, 2023 Category: Psychiatry Authors: Penelope A Lind Dan J Siskind Ian B Hickie Luc ía Colodro-Conde Simone Cross Richard Parker Nicholas G Martin Sarah E Medland Source Type: research
Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder
Res Sq. 2023 Jun 26:rs.3.rs-3068352. doi: 10.21203/rs.3.rs-3068352/v1. Preprint.ABSTRACTThe link between bipolar disorder (BP) and immune dysfunction remains controversial. While epidemiological studies have long suggested an association, recent research has found only limited evidence of such a relationship. To clarify this, we investigated the contributions of immune-relevant genetic factors to the response to lithium (Li) treatment and the clinical presentation of BP. First, we assessed the association of a large collection of immune-related genes (4,925) with Li response, defined by the Retrospective Assessment of the ...
Source: Cell Research - July 18, 2023 Category: Cytology Authors: Marisol Herrera-Rivero Karina Guti érrez-Fragoso Anbupalam Thalamuthu Azmeraw T Amare Mazda Adli Kazufumi Akiyama Nirmala Akula Raffaella Ardau B árbara Arias Jean-Michel Aubry Lena Backlund Frank Bellivier Antonio Benabarre Susanne Bengesser Bhattachar Source Type: research
The impact of quetiapine monotherapy or in combination with lithium on the thyroid function in patients with bipolar depression: A retrospective study
CONCLUSION: Both quetiapine monotherapy and a combined therapy with lithium significantly disturbed thyroid function in patients with bipolar depression, while quetiapine monotherapy seems to be associated with immune dysregulation in the thyroid.PMID:37424160 | DOI:10.1111/cns.14342
Source: CNS Neuroscience and Therapeutics - July 10, 2023 Category: Neuroscience Authors: Lingzhuo Kong Yuting Shen Shaohua Hu Jianbo Lai Source Type: research
Metabolic reprogramming of renal epithelial cells contributes to lithium-induced nephrogenic diabetes insipidus
Biochim Biophys Acta Mol Basis Dis. 2023 May 26:166765. doi: 10.1016/j.bbadis.2023.166765. Online ahead of print.ABSTRACTLithium, mainstay treatment for bipolar disorder, frequently causes nephrogenic diabetes insipidus (NDI) and renal injury. However, the detailed mechanism remains unclear. Here we used the analysis of metabolomics and transcriptomics and metabolic intervention in a lithium-induced NDI model. Mice were treated with lithium chloride (40 mmol/kg chow) and rotenone (ROT, 100 ppm) in diet for 28 days. Transmission electron microscopy showed extensive mitochondrial structural abnormalities in whole nephron. RO...
Source: Biochimica et Biophysica Acta - May 28, 2023 Category: Biochemistry Authors: Mi Liu Mokan Deng Qimei Luo Peng Sun Ailin Liang Xiulin Li Xiaojie Luo Jianyi Pan Wei Zhang Min Mo Xiangdong Guo Xianrui Dou Zhanjun Jia Source Type: research
