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Condition: Encephalitis
Vaccination: Veterinary Vaccinations
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Total 356 results found since Jan 2013.
Efficacy and immunogenicity of a veterinary vaccine candidate against tick-borne encephalitis in dogs
Vaccine. 2023 Sep 14:S0264-410X(23)01089-7. doi: 10.1016/j.vaccine.2023.09.019. Online ahead of print.ABSTRACTTick-borne encephalitis (TBE) is a severe neuroinfection of humans. Dogs are also commonly infected with tick-borne encephalitis virus (TBEV). These infections are usually asymptomatic, but sometimes show clinical signs similar to those seen in humans and can be fatal. To date, there is no TBEV vaccine available for use in dogs. To address this need, a TBEV vaccine candidate for dogs based on inactivated whole virus antigen was developed. The safety, immunogenicity, and efficacy of the vaccine candidate were tested...
Source: Vaccine - September 16, 2023 Category: Allergy & Immunology Authors: Jiri Salat Milan Hunady Pavel Svoboda Lucie Strelcova Petra Strakova Andrea Fortova Martin Palus Daniel Ruzek Source Type: research
Advancements in Nipah virus treatment: Analysis of current progress in vaccines, antivirals, and therapeutics
Immunology. 2023 Sep 15. doi: 10.1111/imm.13695. Online ahead of print.ABSTRACTNipah virus (NiV) causes severe encephalitis in humans. Three NiV strains NiV-Malaysia (NiVM ), NiV Bangladesh (NiVB ), and NiV India (NiVI reported in 2019) have been circulating in South-Asian nations. Sporadic outbreak observed in South-East Asian countries but human to human transmission raises the concern about its pandemic potential. The presence of the viral genome in reservoir bats has further confirmed that NiV has spread to the African and Australian continents. NiV research activities have gained momentum to achieve specific preparedn...
Source: Immunology - September 15, 2023 Category: Allergy & Immunology Authors: Gayatree Mishra Vishal Prajapat Debasis Nayak Source Type: research
A roadmap for developing Venezuelan equine encephalitis virus (VEEV) vaccines: Lessons from the past, strategies for the future
Int J Biol Macromol. 2023 Jun 21:125514. doi: 10.1016/j.ijbiomac.2023.125514. Online ahead of print.ABSTRACTVenezuelan equine encephalitis (VEE) is a zoonotic infectious disease caused by the Venezuelan equine encephalitis virus (VEEV), which can lead to severe central nervous system infections in both humans and animals. At present, the medical community does not possess a viable means of addressing VEE, rendering the prevention of the virus a matter of paramount importance. Regarding the prevention and control of VEEV, the implementation of a vaccination program has been recognized as the most efficient strategy. Neverth...
Source: International Journal of Biological Macromolecules - June 23, 2023 Category: Biochemistry Authors: Lulu Han Shuai Song Huilin Feng Jing Ma Wenqiang Wei Fusheng Si Source Type: research
Human monkeypox virus in the shadow of the COVID-19 pandemic
CONCLUSIONS: monkeypox is a viral disease caused by the monkeypox virus (MPXV), which is primarily found in central and western Africa. The disease is transmitted from animals to humans and presents symptoms similar to those of smallpox, including fever, headache, muscle aches, and a rash. Monkeypox can lead to complications such as secondary integument infection, bronchopneumonia, sepsis, and encephalitis, as well as corneal infection that can result in blindness. There is no specific clinically proven treatment for monkeypox, and treatment is primarily supportive. However, antiviral drugs and vaccines are available for c...
Source: Cancer Control - June 3, 2023 Category: Cancer & Oncology Authors: Almu'atasim Khamees Sajeda Awadi Khayry Al-Shami Hayat Abu Alkhoun Sharaf F Al-Eitan Ahmad Malek Alsheikh Ahmad Saeed Raed M Al-Zoubi Mazhar Salim Al Zoubi Source Type: research
Live-attenuated Japanese encephalitis virus inhibits glioblastoma growth and elicits potent antitumor immunity
In this study, we investigated the safety of a live attenuated Japanese encephalitis vaccine strain (JEV-LAV) virus as an oncolytic virus for intracerebral injection in mice. We infected different GBM cell lines with JEV-LAV to investigate whether it had growth inhibitory effects on GBM cell lines in vitro. We used two models for evaluating the effect of JEV-LAV on GBM growth in mice. We investigated the antitumor immune mechanism of JEV-LAV through flow cytometry and immunohistochemistry. We explored the possibility of combining JEV-LAV with PD-L1 blocking therapy. This work suggested that JEV-LAV had oncolytic activity a...
Source: Cancer Control - April 28, 2023 Category: Cancer & Oncology Authors: Zhongbing Qi Jing Zhao Yuhua Li Bin Zhang Shichuan Hu Yanwei Chen Jinhu Ma Yongheng Shu Yunmeng Wang Ping Cheng Source Type: research
Dairy milk from cow and goat as a sentinel for tick-borne encephalitis virus surveillance
Comp Immunol Microbiol Infect Dis. 2023 Feb 17;95:101958. doi: 10.1016/j.cimid.2023.101958. Online ahead of print.ABSTRACTTick-borne encephalitis (TBE) is one of the most severe human tick-borne diseases in Europe. It is caused by the tick-borne encephalitis virus (TBEV), which is transmitted to humans mainly via bites of Ixodes ricinus or I. persulcatus ticks. The geographical distribution and abundance of I. ricinus is expanding in Sweden as has the number of reported human TBE cases. In addition to tick bites, alimentary TBEV infection has also been reported after consumption of unpasteurized dairy products. So far, no ...
Source: Comparative immunology, microbiology and infectious diseases. - March 9, 2023 Category: Allergy & Immunology Authors: Anna Omazic Am élie Wallenhammar Elina Lahti Naveed Asghar Alexander Hanberger Marika Hjertqvist Magnus Johansson Ann Albihn Source Type: research
Rabies, the cause of fatal encephalitis
Salud Publica Mex. 2023 Jan 2;65(1, ene-feb):93-98. doi: 10.21149/13899.ABSTRACTTo describe the clinical progression and medical protocols applied in a 41 year old man who was bited by a bat three months before. The patient did not ask for medical care until acute tremor and pain in the right thoracic limb and hydro-phobia started. For a history of a wild animal bite associated with a unique clinical condition, we suspected of rabies encephalitis, confirming the diagnostic by pathology after his death. This case ocurred in Guadalajara, Jalisco, México, in April, 2022. The last case of human rabies reported in Jalisco seco...
Source: Salud Publica de Mexico - February 7, 2023 Category: Epidemiology Authors: Manuel Elizaf án Torres-Pérez Idarmis Brisseida Reyes-Cort és Erik Mauricio Romero-Ramos Daniel Alejandro Reyna-Osorio M ónica Serrano-Murillo Jorge Arturo Mart ínez-Manjarrez Alfredo Kuri- Álvarez Jes ús Vladimir Arriaga-Ponce Erick Sierra-D íaz Source Type: research
