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Condition: Diabetes Mellitus
Procedure: Kidney Transplant

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Total 2601 results found since Jan 2013.

Self-organized insulin-producing β-cells differentiated from human omentum-derived stem cells and their in vivo therapeutic potential
CONCLUSIONS: Our findings suggest that the FGF2-immobilized matrix can support initial cell adhesion, maturation, and glucose-stimulated insulin secretion within the host microenvironment. Such a cell culture platform can offer novel strategies to obtain functional pancreatic β-cells from patient-specific cell sources, ultimately enabling better treatment for diabetes mellitus.PMID:37644502 | DOI:10.1186/s40824-023-00419-1
Source: Cell Research - August 29, 2023 Category: Cytology Authors: Ji Hoon Jeong Ki Nam Park Joo Hyun Kim KyungMu Noh Sung Sik Hur Yunhye Kim Moonju Hong Jun Chul Chung Jae Hong Park Jongsoon Lee Young-Ik Son Ju Hun Lee Sang-Heon Kim Yongsung Hwang Source Type: research

A Case of Herpes Zoster Ophthalmicus in a Recently Transplanted Renal Patient
Cureus. 2023 Jun 24;15(6):e40899. doi: 10.7759/cureus.40899. eCollection 2023 Jun.ABSTRACTHerpes Zoster Ophthalmicus (HZO) is a common manifestation of the reactivated Varicella Zoster virus, primarily affecting the eye and trigeminal nerve. This case study presents the clinical course of a 51-year-old male who underwent a renal transplant due to end-stage renal disease, further complicating the management of HZO. The patient's medical history also includes hypertension, type 2 diabetes mellitus, chronic kidney disease (CKD), cerebrovascular accident (CVA), and retinal detachment. Upon examination, the diagnosis of HZO was...
Source: Herpes - July 26, 2023 Category: Infectious Diseases Authors: Mohamad Jabin Zaryab Alam Evan Chung Mojahed Shalabi Bismah Siddiqui Source Type: research

Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1 to 3) non-diabetic chronic kidney disease
CONCLUSIONS: There is currently insufficient evidence to determine the effectiveness of ACEi or ARB in patients with stage 1 to 3 CKD who do not have DM. The available evidence is overall of very low certainty and high risk of bias. We have identified an area of large uncertainty for a group of patients who account for most of those diagnosed as having CKD.PMID:37466151 | DOI:10.1002/14651858.CD007751.pub3
Source: Cochrane Database of Systematic Reviews - July 19, 2023 Category: General Medicine Authors: Tess E Cooper Claris Teng David J Tunnicliffe Brydee A Cashmore Giovanni Fm Strippoli Source Type: research

Prediction of diabetes mellitus after kidney transplantation using patient-specific induced pluripotent stem cells
CONCLUSION: Taken together, these results indicate that PP cells of the DM group showed low developmental potency accompanied by a significantly different genetic background compared with the non-DM group. Thus, genetic analysis can be used to predict the risk of DM before KT.PMID:37448282 | DOI:10.23876/j.krcp.22.251
Source: Cell Research - July 14, 2023 Category: Cytology Authors: Sun Woo Lim Yoo Jin Shin Sheng Cui Eun Jeong Ko Byung Ha Chung Chul Woo Yang Source Type: research

Interleukin-6 to albumin ratio as a superior predictor of mortality in end stage kidney disease patients
CONCLUSIONS: Higher IL-6 to albumin ratio was independently associated with significantly higher all-cause mortality risk in incident dialysis patients. These results suggest that IAR may provide useful prognostic information in patients with CKD.PMID:37231796 | DOI:10.1159/000531191
Source: American Journal of Nephrology - May 26, 2023 Category: Urology & Nephrology Authors: Xiejia Li Abdul Rashid Qureshi Mohamed E Suliman Olof Heimburger Peter Barany Peter Stenvinkel Bengt Lindholm Source Type: research

Assessing the Relationship Between Gut Microbiota and Posttransplant Diabetes Mellitus
CONCLUSIONS: To our knowledge, this is the first comprehensive analysis of the gut microbiota from posttransplant diabetes mellitus recipients. The microbial composition of stool samples of post- transplant diabetes mellitus recipients was significantly different from recipients without diabetes and with preexisting diabetes. The number of bacteria producing short-chain fatty acids decreased, whereas pathogenic bacteria increased.PMID:37154595 | DOI:10.6002/ect.2022.0366
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 8, 2023 Category: Transplant Surgery Authors: Jianhua Long Zhimin Feng Huidong Zhou Jia Liu Jianglei Zhang Jun Ouyang Source Type: research