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Condition: Dementia
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Total 430 results found since Jan 2013.

Association between carotid stenosis or lacunar infarction and incident dementia in patients with vascular risk factors
ConclusionsThis study demonstrated that carotid stenosis had little association with dementia, but lacunar infarction had a significant association. The impact of SVD on dementia could be much greater than that of LVD.
Source: European Journal of Neurology - August 28, 2014 Category: Neurology Authors: K. Kitagawa, K. Miwa, Y. Yagita, S. Okazaki, M. Sakaguchi, H. Mochizuki Tags: Original Article Source Type: research

Prescription sleeping pills linked to Alzheimer's risk
Conclusion This case control study has suggested that long-term use of benzodiazepines (over six months) may be linked with an increased risk of Alzheimer’s disease in older people. These findings are reported to be similar to other previous studies, but add weight to these by showing that risk increases with increasing length of exposure to the drugs, and with those benzodiazepines that remain in the body for longer. The strengths of this study include that it could establish when people started taking benzodiazepines and when they had their diagnosis using medical insurance records, rather than having to ask people to ...
Source: NHS News Feed - September 10, 2014 Category: Consumer Health News Tags: Neurology Mental health Source Type: news

Report on the 5‘th scientific meeting of the “Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie” (NEUROWIND e.V.) held in Motzen, Germany, Oct. 25th – Oct. 27th, 2013
Abstract From october 25th - 27th 2013, the 5th NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. This year more than 60 doctoral students and postdocs from over 25 different groups working in German university hospitals or research institutes attended the meeting to discuss their latest findings in the fields of neuroimmunology, neurodegeneration and neurovascular research. All participants appreciated the stimulating environment in Motzen, Brandenburg, and people took the opportunity for scientific exchange, discussion about ongoing projects and already started further collaborations. Like in the...
Source: Experimental and Translational Stroke Medicine - December 11, 2013 Category: Neurology Source Type: research

Risk of dementia in elderly patients with the use of proton pump inhibitors
Abstract Drugs that modify the risk of dementia in the elderly are of potential interest for dementia prevention. Proton pump inhibitors (PPIs) are widely used to reduce gastric acid production, but information on the risk of dementia is lacking. We assessed association between the use of PPIs and the risk of dementia in elderly people. Data were derived from a longitudinal, multicenter cohort study in elderly primary care patients, the German Study on Aging, Cognition and Dementia in Primary Care Patients (AgeCoDe), including 3,327 community-dwelling persons aged ≥75 years. From follow-up 1 to follow-up 4 (fol...
Source: European Archives of Psychiatry and Clinical Neuroscience - October 24, 2014 Category: Neuroscience Source Type: research

Risk of dementia in elderly patients with the use of proton pump inhibitors.
Authors: Haenisch B, von Holt K, Wiese B, Prokein J, Lange C, Ernst A, Brettschneider C, König HH, Werle J, Weyerer S, Luppa M, Riedel-Heller SG, Fuchs A, Pentzek M, Weeg D, Bickel H, Broich K, Jessen F, Maier W, Scherer M Abstract Drugs that modify the risk of dementia in the elderly are of potential interest for dementia prevention. Proton pump inhibitors (PPIs) are widely used to reduce gastric acid production, but information on the risk of dementia is lacking. We assessed association between the use of PPIs and the risk of dementia in elderly people. Data were derived from a longitudinal, multicenter cohort s...
Source: European Archives of Psychiatry and Clinical Neuroscience - October 25, 2014 Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research

Physical activity in the elderly is associated with improved executive function and processing speed: the LADIS Study
ConclusionOur findings confirm previous findings of a positive effect of physical activity on cognitive functions in elderly subjects, and further extends these by showing that the association is also present in patients with ARWMC. Copyright © 2014 John Wiley & Sons, Ltd.
Source: International Journal of Geriatric Psychiatry - November 3, 2014 Category: Geriatrics Authors: Kristian Steen Frederiksen, Ana Verdelho, Sofia Madureira, Hansjörg Bäzner, John T. O'Brien, Franz Fazekas, Philip Scheltens, Reinhold Schmidt, Anders Wallin, Lars‐Olof Wahlund, Timo Erkinjunttii, Anna Poggesi, Leonardo Pantoni, Domenico Inzitari, Gun Tags: Research Article Source Type: research

Correction to Wendell, Waldstein, and Zonderman (2013).
Conclusions: Overall, results indicate nonlinear longitudinal relations of total cholesterol to cognitive decline. Whereas higher cholesterol levels were associated with cognitive decline in the middle-aged or young-old, lower cholesterol levels were related to cognitive decline among old-old participants. (PsycINFO Database Record (c) 2014 APA, all rights reserved)
Source: Neuropsychology - September 22, 2014 Category: Neurology Authors: No authorship indicated Source Type: research

Development and validation of a brief dementia screening indicator for primary care
Conclusions The Dementia Screening Indicator is a simple tool that may be useful in primary care settings to identify high-risk patients to target for cognitive screening.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2014 Category: Geriatrics Source Type: research

Protocol for REducing Anti-Psychotic use in residential care-Huntington Disease (REAP-HD): a pilot cluster randomised controlled trial of a multifaceted intervention for health professionals
This study aims to test the hypothesis that the multifaceted REducing Anti-Psychotic use in residential care-Huntington Disease (REAP-HD) programme is more effective than standard staff education (SSE) in reducing antipsychotic use for people with HD in residential care facilities (RCF). Methods and analysis this is a cluster randomised controlled trial with blinded outcome assessment. The study population is healthcare professionals looking after people with HD in individual RCF, in the state of New South Wales. Each RCF will be centrally randomised to the REAP-HD programme or the comparator, SSE. Blinded outcome assessm...
Source: BMJ Open - December 2, 2014 Category: Journals (General) Authors: Loy, C. T., Hayen, A., McKinnon, C. Tags: Open access, Mental health, Neurology Protocol Source Type: research

Comparisons of clinical symptoms in biomarker‐confirmed Alzheimer's disease, dementia with Lewy bodies, and frontotemporal dementia patients in a local memory clinic
ConclusionMemory impairment and apathy are not useful discriminative symptoms in diagnosing AD, DLB, and FTD. Apraxia favours AD. Hallucinations, particularly well‐formed visual hallucinations, favour DLB. Overall, behavioural and neuropsychiatric symptoms of dementia symptoms are common among the three groups of dementia patients.
Source: Psychogeriatrics - December 1, 2014 Category: Geriatrics Authors: Yat Fung Shea, Joyce Ha, Leung‐Wing Chu Tags: ORIGINAL ARTICLE Source Type: research

Improving Dementia Health Literacy Using the FLOW Mnemonic: Pilot Findings From the Old SCHOOL Hip-Hop Program
Conclusions. This study suggests our hip-hop health education model may be an effective method to improve AD health literacy.
Source: Health Education - January 12, 2015 Category: Health Management Authors: Noble, J. M., Hedmann, M. G., Williams, O. Tags: Regular Articles Source Type: research

Associations Between Oral Health and Risk of Dementia in a 37‐Year Follow‐Up Study: The Prospective Population Study of Women in Gothenburg
ConclusionIn most of the analyses, lower tooth count was not associated with dementia, although a significant association was found for one of the three examinations. Further research may benefit from more‐direct measures of dental and periodontal disease.
Source: Journal of the American Geriatrics Society - January 17, 2015 Category: Geriatrics Authors: Robert Stewart, Ulrika Stenman, Magnus Hakeberg, Catharina Hägglin, Deb Gustafson, Ingmar Skoog Tags: Brief Reports Source Type: research

Media dementia scare over hay fever and sleep drugs
Conclusion This large US prospective cohort study suggests a link between those taking high levels of anticholinergic medicines for more than three years and developing dementia in adults over 65. The main statistically significant finding was in a group taking the equivalent of any of the following medications daily for more than three years: xybutynin chloride, 5mg chlorpheniramine maleate, 4mg olanzapine, 2.5mg meclizine hydrochloride, 25mg doxepin hydrochloride, 10mg These are not unrealistic doses of medicine, so the results may be applicable to a significant proportion of older adults. The main lim...
Source: NHS News Feed - January 27, 2015 Category: Consumer Health News Tags: Medication Neurology Source Type: news

Mid-Life Proteinuria and Late-Life Cognitive Function and Dementia in Elderly Men: The Honolulu-Asia Aging Study.
CONCLUSION:: Mid-life proteinuria was an independent predictor for late-life incident all-cause dementia and cognitive decline over 8 years. PMID: 25626635 [PubMed - as supplied by publisher]
Source: Alzheimer Disease and Associated Disorders - February 1, 2015 Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research

What are the predictors of an inadequate preparation?
Predictors of an inadequate bowel preparation include: history of stroke or dementia, opioid use, male sex, calcium channel blocker use, and antidepressant use. Comprehensive patient education is an area for further research to improve quality of bowel preparation.
Source: American Journal of Surgery - February 11, 2015 Category: Surgery Authors: Ruby Yee, Shiana Manoharan, Christine Hall, Allen Hayashi Tags: Clinical Surgery--International Source Type: research