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Condition: Dementia
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Total 430 results found since Jan 2013.

Sleep Complaints and Incident Disability in a Community-Based Cohort Study of Older Persons.
CONCLUSION: Non-disabled older adults with more sleep complaints have an increased risk of developing disability. PMID: 23567404 [PubMed - as supplied by publisher]
Source: The American Journal of Geriatric Psychiatry - April 10, 2013 Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research

UCLA Nursing research on women and heart disease among key topics at nursing conference
New findings on the role gender plays in the diagnosis, treatment and prevention of heart disease will be among the research topics highlighted by faculty members and students from the UCLA School of Nursing at the annual Western Institute of Nursing Conference, which runs from April 11 to 13 in Anaheim, Calif.   At a special state-of-the-science panel on Saturday, April 13, UCLA professor Lynn V. Doering will present a review of gender differences in identification, treatment and outcomes for cardiovascular disease, with a focus on coronary atherosclerosis, heart failure and stroke. During the same panel, UCLA profes...
Source: UCLA Newsroom: Health Sciences - April 9, 2013 Category: Universities & Medical Training Source Type: news

Background of the Sociedad Neurologica Argentina: Current state and concerns about neurologic education
Neurology in Argentina emerged toward the end of the 19th century, following the origin of the specialty in Europe. Its development can be divided into 3 periods. The first is the specialty of neurology as part of internal medicine. Doctoral theses and publication about neurologic topics are found early in the history of medicine, but merged into internal medicine. The second period is the foundation of clinical neurology under the typical European influence, mainly French, when the first neurologists appear. This period started in 1885 with the creation of the Hospital San Roque de Buenos Aires' first nervous diseases dep...
Source: Neurology - May 20, 2013 Category: Neurology Authors: Correale, J., Allegri, R. F., Pelli-Noble, R. F. Tags: History of Neurology, CME, Methods of education GLOBAL PERSPECTIVES Source Type: research

Optimal Blood Pressure for Cognitive Function: Findings from an Elderly African‐American Cohort Study
ConclusionHigh and low BP were associated with poorer cognitive performance. A joint optimal region of SBP and DBP for cognitive function has been identified, which may provide useful clinical information on optimal BP control in cognitive health and lead to better quality of life for elderly adults.
Source: Journal of the American Geriatrics Society - May 6, 2013 Category: Geriatrics Authors: Hai Liu, Sujuan Gao, Kathleen S. Hall, Frederick W. Unverzagt, Kathleen A. Lane, Christopher M. Callahan, Hugh C. Hendrie Tags: Clinical Investigations Source Type: research

Risk factors for dementia with Lewy bodies: A case-control study
Conclusion: DLB risk factors are an amalgam of those for AD and PD. Smoking and education, which have opposing risk effects on AD and PD, are not risk factors for DLB; however, depression and low caffeine intake, both risk factors for AD and PD, increase risk of DLB more strongly than in either.
Source: Neurology - August 26, 2013 Category: Neurology Authors: Boot, B. P., Orr, C. F., Ahlskog, J. E., Ferman, T. J., Roberts, R., Pankratz, V. S., Dickson, D. W., Parisi, J., Aakre, J. A., Geda, Y. E., Knopman, D. S., Petersen, R. C., Boeve, B. F. Tags: Parkinson's disease/Parkinsonism, All Cognitive Disorders/Dementia, Alzheimer's disease, Dementia with Lewy bodies, Case control studies ARTICLE Source Type: research

Substantial effects of apolipoprotein E ε4 on memory decline in very old age: longitudinal findings from a population-based sample
We examined associations between the apolipoprotein E (APOE) ε4 allele and levels of performance and rates of change in cognition in late life taking incident dementia into account. The sample consisted of 482 nondemented individuals, aged 80 years and older at baseline, drawn from the OCTO twin study. A battery of 10 cognitive tests was administered at 5 occasions with measurements intervals of 2 years. We fitted hierarchical linear models with time specified as time to death and controlled for baseline age, sex, education, stroke, cardiovascular disease, hypertension, diabetes, and incident dementia. The ε4 allele was ...
Source: Neurobiology of Aging - July 15, 2013 Category: Neuroscience Authors: Marcus Praetorius, Valgeir Thorvaldsson, Linda B. Hassing, Boo Johansson Tags: Regular Articles Source Type: research

Asymptomatic cervicocerebral atherosclerosis, intracranial vascular resistance and cognition: The AsIA-Neuropsychology Study
Conclusions: Carotid plaques and increased intracranial vascular resistance are independently associated with low cognitive functioning in Caucasian stroke and dementia-free subjects. We failed to find an independent association of intracranial large vessel stenosis with cognitive performance.Highlights:
Source: Atherosclerosis - September 26, 2013 Category: Cardiology Authors: Jorge López-Olóriz, Elena López-Cancio, Juan F. Arenillas, María Hernández, Marta Jiménez, Laura Dorado, Maite Barrios, Juan José Soriano-Raya, Júlia Miralbell, Cynthia Cáceres, Rosa Forés, Guillem Pera, Antoni Dávalos, Maria Mataró Tags: Clinical & Population Research - Imaging Measurement of Vessel Health Source Type: research

Lack of parental warmth, abuse in childhood linked to multiple health risks in adulthood
This study was also supported by the MacArthur Research Network on Socioeconomic Status and Health through grants from the John D. and Catherine T. MacArthur Foundation, and by grant T32-MH19925 and the Cousins Center for Psychoneuroimmunology at the UCLA.   The UCLA Cousins Center for Psychoneuroimmunology encompasses an interdisciplinary network of scientists working to advance the understanding of psychoneuroimmunology by linking basic and clinical research programs and by translating findings into clinical practice. The center is affiliated with the Semel Institute for Neuroscience and Human Behavior and the David...
Source: UCLA Newsroom: Health Sciences - October 1, 2013 Category: Universities & Medical Training Source Type: news

Grey matter correlations of cognitive impairment in early parkinson's disease: the incidence of cognitive impairment in cohorts with longitudinal evaluation-parkinson's disease (icicle-pd) study
Conclusion GM loss is not present in newly diagnosed PD, either in patients with PD–MCI or PD–NC. These data are consistent with neuropathological studies suggesting that GM loss occurs with disease progression and is not prominent in early PD where the neurodegenerative process is more limited.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Duncan, G. W., Firbank, M. J., Yarnall, A. J., Barker, R. A., O'Brien, J. T., Burn, D. J. Tags: Dementia, Drugs: CNS (not psychiatric), Parkinson's disease, Stroke, Memory disorders (psychiatry), Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 Octo Source Type: research

Depressive symptoms predict cognitive decline and dementia in older people independently of cerebral white matter changes: the LADIS study
Conclusions DS are associated with an increase risk of cognitive decline, independent of the effect of WMC, probably due to an additive or synergistic effect. In this context, DS probably represent a subtle ongoing organic dysfunction
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Verdelho, A., Madureira, S., Moleiro, C., Ferro, J. M., O'Brien, J. T., Poggesi, A., Pantoni, L., Fazekas, F., Scheltens, P., Waldemar, G., Wallin, A., Erkinjuntti, T., Inzitari, D., on behalf of the LADIS Study Tags: Long term care, Dementia, Stroke, Memory disorders (psychiatry), Mood disorders (including depression), Psychiatry of old age Cognition Source Type: research

Subclinical atherosclerotic calcification and cognitive functioning in middle-aged adults: The CARDIA study
We examined the association of coronary artery and abdominal aortic calcified plaque (CAC and AAC, respectively) with cognitive functioning in middle-aged adults.Methods: This cross-sectional study included 2510 black and white adults (age: 43–55 years) without heart disease or stroke who completed a year 25 follow-up exam (2010–11) as part of the Coronary Artery Risk Development in Young Adults Study. CAC and AAC were measured with non-contrast computed tomography. Cognition was assessed with the Digit Symbol Substitution Test (DSST) (psychomotor speed), Stroop Test (executive function), and Rey Auditory Verbal Learni...
Source: Atherosclerosis - October 14, 2013 Category: Cardiology Authors: Jared P. Reis, Lenore J. Launer, James G. Terry, Catherine M. Loria, Adina Zeki Al Hazzouri, Stephen Sidney, Kristine Yaffe, David R. Jacobs, Christopher T. Whitlow, Na Zhu, J. Jeffrey Carr Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research

How experienced community neurologists make diagnoses during clinical encounters
We describe 3 core domains of diagnosis: 1) clinical (C), 2) laboratory and electrodiagnostics (L), and 3) neuroimaging (N). Neurologists were uniform in their practices across these domains except within the clinical domain, where the physical examination varied considerably among clinicians. All neurologists coordinated findings from the 3 domains to arrive at a final diagnosis. This practice of coordination varied across common disease categories (e.g., meningitis vs dementia). To codify this variance, we developed a provisional model of diagnostic practice derived from the data consisting of a 3-point coordinate shorth...
Source: Neurology - October 14, 2013 Category: Neurology Authors: Dhand, A., Engstrom, J., Dhaliwal, G. Tags: Cost effectiveness/economic, Decision analysis, All Clinical Neurology, Methods of education CONTEMPORARY ISSUES Source Type: research

Being bilingual may slow the onset of dementia
Conclusion This consecutive series of people treated at a specialist dementia clinic in India found that people with dementia who are bilingual developed dementia later than people who were monolingual. It is highly plausible that activities engaged in over a lifetime that increase our cognitive ability – such as understanding two or more languages – may have a protective effect against cognitive decline. However, this study cannot prove that being bilingual is directly protective against developing dementia. This study only characterised differences within a group of people who all developed dementia, rather than loo...
Source: NHS News Feed - November 8, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Neurology Older people Source Type: news

Healthy Brain Aging and the Multiple Reserve Hypothesis
Those of us in the medical professions are trained since early years to be concerned about the many forms and mechanisms of disease. We strive to be aggressive in our diagnosis and treatment of disease and in our research on disease mechanisms, known as pathogenesis. Often lost in our disease focused frame of mind is appreciation for the generation and maintenance of health, known as salutogenesis. The absence of disease is not the same as the presence of health, especially with aging. Many older people do not have major illnesses, but remain limited in their functional capacities. It is vital for persons of all ages, as w...
Source: Neurobiology of Aging - December 10, 2013 Category: Neuroscience Authors: Robert Frıedland Tags: Meeting Abstracts Source Type: research

Test could give two-year warning for Alzheimer's
Conclusion The researchers suggest that Alzheimer's disease can be predicted with an accuracy of 87.5% when thinning of the cortex in the right anterior cingulated gyrus is seen on MRI, alongside test results suggesting problems with recall and recognition. This research does not indicate a new "test", as MRI and psychological testing are standard procedures when investigating the signs and symptoms of dementia. What is novel in this approach is looking at a specific combination of results as a potential way of predicting which people with MCI may develop Alzheimer's disease. While this form of testing would be b...
Source: NHS News Feed - December 9, 2013 Category: Consumer Health News Tags: Neurology Source Type: news