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Specialty: Allergy & Immunology
Condition: Autoimmune Disease
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Total 1596 results found since Jan 2013.
Ginger Consumption May Mitigate Neutrophil Dysfunction Ginger Consumption May Mitigate Neutrophil Dysfunction
An oral ginger extract was associated with reduced action of the neutrophil activity associated with the development of autoimmune and inflammatory diseases.Medscape Medical News
Source: Medscape Allergy Headlines - September 22, 2023 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news
European Commission Approves First Tocilizumab Biosimilar European Commission Approves First Tocilizumab Biosimilar
The biosimilar, commercially called Tyenne, is indicated to treat several autoimmune diseases as well as cytokine release syndrome and COVID-19.Medscape Medical News
Source: Medscape Allergy Headlines - September 21, 2023 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news
An updated review of pandas/pans disease also known as idiopathic autoimmune encephalitis: what the allergist should know
CONCLUSION: Due to the complexity and variability in how patients with IAE may present to the Allergist/Immunologist office, an interdisciplinary approach is imperative to provide patients with the best medical care. Still, additional research is needed to further elucidate the mechanism(s) and optimal treatment algorithm for IAE in order to facilitate broader recognition and acceptance of this condition by the medical community.PMID:37634580 | DOI:10.1016/j.anai.2023.08.022
Source: Annals of Allergy, Asthma and Immunology - August 27, 2023 Category: Allergy & Immunology Authors: Hannah Hardin Wenhai Shao Jonathan A Bernstein Source Type: research
An updated review of pandas/pans disease also known as idiopathic autoimmune encephalitis: what the allergist should know
CONCLUSION: Due to the complexity and variability in how patients with IAE may present to the Allergist/Immunologist office, an interdisciplinary approach is imperative to provide patients with the best medical care. Still, additional research is needed to further elucidate the mechanism(s) and optimal treatment algorithm for IAE in order to facilitate broader recognition and acceptance of this condition by the medical community.PMID:37634580 | DOI:10.1016/j.anai.2023.08.022
Source: Annals of Allergy, Asthma and Immunology - August 27, 2023 Category: Allergy & Immunology Authors: Hannah Hardin Wenhai Shao Jonathan A Bernstein Source Type: research
An updated review of pandas/pans disease also known as idiopathic autoimmune encephalitis: what the allergist should know
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), further subcategorized as Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus (PANDAS), is a form of Idiopathic Autoimmune Encephalitis (IAE). Post-streptococcal autoimmunity seen in IAE manifests as various neuropsychiatric symptoms such as obsessive rituals, tics, anxiety, depression, and many others. IAE has clinically heterogeneous phenotypes that make accurate diagnosing difficult, though diagnostic testing such as the Cunningham Panel increases the likelihood of finding effective treatments.
Source: Annals of Allergy, Asthma and Immunology - August 25, 2023 Category: Allergy & Immunology Authors: Hannah Hardin, Wenhai Shao, Jonathan A. Bernstein Tags: Review Source Type: research
CAR-T Therapy for NHL Treats Concurrent Rheumatic Disease CAR-T Therapy for NHL Treats Concurrent Rheumatic Disease
CAR –T cell therapy for non-Hodgkin lymphoma appeared as safe and effective in patients with rheumatic autoimmune disease as in those without and also improved control of the underlying autoimmunity.Medscape Medical News
Source: Medscape Allergy Headlines - August 24, 2023 Category: Allergy & Immunology Tags: Rheumatology Source Type: news
How Does Global Warming Contribute to Disorders Originating from an Impaired Epithelial Barrier?
Ann Allergy Asthma Immunol. 2023 Aug 22:S1081-1206(23)00588-4. doi: 10.1016/j.anai.2023.08.010. Online ahead of print.ABSTRACTThe epithelial barrier represents the point of contact between the host and the external environment. It is the first line of defense against external insults in the skin, gastrointestinal and upper and lower respiratory tracts. The steep increase in chronic disorders in recent decades, including allergies and autoimmune disorders, has prompted studies to investigate the immune mechanisms of their underlying pathogeneses, all of which point to a thought-provoking shared finding: disrupted epithelial...
Source: Annals of Allergy, Asthma and Immunology - August 24, 2023 Category: Allergy & Immunology Authors: Cevdet Ozdemir Umut Can Kucuksezer Ismail Ogulur Yagiz Pat Duygu Yazici Ioana Agache Marek Jutel Kari C Nadeau M übeccel Akdis Cezmi A Akdis Source Type: research
Autoimmune Inflammatory Eye Disease: Demystifying Clinical Presentations for the Internist
AbstractPurpose of ReviewProvide a framework for recognizing key symptoms and clinical findings in patients with autoimmune inflammatory eye disease.Recent FindingsThe most common manifestations of autoimmune inflammatory eye disease are episcleritis, scleritis, uveitis (anterior, intermediate, posterior, and panuveitis), and keratoconjunctivitis sicca. Etiologies can be idiopathic or in association with a systemic autoimmune condition. Referral of patients who may have scleritis is critical for patients presenting with red eyes. Referral of patients who may have uveitis is critical for patients presenting often with float...
Source: Current Allergy and Asthma Reports - August 1, 2023 Category: Allergy & Immunology Source Type: research
Shared Pathogenicity Features and Sequences between EBV, SARS-CoV-2, and HLA Class I Molecule-binding Motifs with a Potential Role in Autoimmunity
AbstractEpstein-Barr virus (EBV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are extraordinary in their ability to activate autoimmunity as well as to induce diverse autoimmune diseases. Here we reviewed the current knowledge on their relation. Further, we suggested that molecular mimicry could be a possible common mechanism of autoimmunity induction in the susceptible individuals infected with SARS-CoV-2. Molecular mimicry between SARS-CoV-2 and human proteins, and EBV and human proteins, are present. Besides, relation of the pathogenicity associated with both coronavirus diseases and EBV supports the...
Source: Clinical Reviews in Allergy and Immunology - July 28, 2023 Category: Allergy & Immunology Source Type: research
RelB-deficient autoinflammatory pathology presents as interferonopathy, but in mice is IFN-independent
Autoimmune diseases are leading causes of ill health and morbidity and have diverse etiology. Two signaling pathways are key drivers of autoimmune pathology, interferon and NF κB/RelA, defining the two broad labels of interferonopathies and relopathies. Prior work established that genetic loss of function of the NFκB subunit RelB leads to autoimmune and inflammatory pathology in mice and humans.
Source: Journal of Allergy and Clinical Immunology - July 14, 2023 Category: Allergy & Immunology Authors: Hector I. Navarro, Yi Liu, Anna Fraser, Diane Lefaudeux, Jennifer J. Chia, Linda Vong, Chaim M. Roifman, Alexander Hoffmann Source Type: research
RelB-deficient autoinflammatory pathology presents as interferonopathy, but in mice is interferon-independent
Autoimmune diseases are leading causes of ill health and morbidity and have diverse etiology. Two signaling pathways are key drivers of autoimmune pathology, interferon and nuclear factor- κB (NF-κB)/RelA, defining the 2 broad labels of interferonopathies and relopathies. Prior work has established that genetic loss of function of the NF-κB subunit RelB leads to autoimmune and inflammatory pathology in mice and humans.
Source: Journal of Allergy and Clinical Immunology - July 14, 2023 Category: Allergy & Immunology Authors: H éctor I. Navarro, Yi Liu, Anna Fraser, Diane Lefaudeux, Jennifer J. Chia, Linda Vong, Chaim M. Roifman, Alexander Hoffmann Source Type: research
Autoimmune Inflammatory Eye Disease: Demystifying Clinical Presentations for the Internist
AbstractPurpose of ReviewProvide a framework for recognizing key symptoms and clinical findings in patients with autoimmune inflammatory eye disease.Recent FindingsThe most common manifestations of autoimmune inflammatory eye disease are episcleritis, scleritis, uveitis (anterior, intermediate, posterior, and panuveitis), and keratoconjunctivitis sicca. Etiologies can be idiopathic or in association with a systemic autoimmune condition. Referral of patients who may have scleritis is critical for patients presenting with red eyes. Referral of patients who may have uveitis is critical for patients presenting often with float...
Source: Current Allergy and Asthma Reports - July 12, 2023 Category: Allergy & Immunology Source Type: research
Autoimmune Connective Tissue Diseases: Systemic Lupus Erythematosus and Rheumatoid Arthritis
Systemic lupus erythematosus and rheumatoid arthritis are just 2 of several autoimmune connective tissue diseases that are primarily chronic in nature but can present to the emergency department by virtue of an acute exacerbation of disease. Beyond an acute exacerbation of disease, their predilection for invading multiple organ systems lends itself to the potential for patients presenting to the emergency department with either a single or isolated symptom or a myriad of signs and/or symptoms indicative of a degree of disease complexity and severity that warrant timely recognition and resuscitation.
Source: Immunology and Allergy Clinics of North America - July 1, 2023 Category: Allergy & Immunology Authors: Jonathan Rose Source Type: research
Activated Phosphoinositide 3-Kinase δ Syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity
When comparing the phenotypic overlap of autoimmune-lymphoproliferative inborn errors of immunity (IEI) APDS demonstrates high penetrance, low genetic heterogeneity, early-onset as risk factor for severe disease and high phenotypic overlap with other IEIs.
Source: Journal of Allergy and Clinical Immunology - June 27, 2023 Category: Allergy & Immunology Authors: Maria Elena Maccari, Martin Wolkewitz, Charlotte Schwab, Tiziana Lorenzini, Jennifer W. Leiding, Nathalie Aladjdi, Hassan Abolhassani, Wadih Abou-Chahla, Alessandro Aiuti, Saba Azarnoush, Safa Baris, Vincent Barlogis, Federica Barzaghi, Ulrich Baumann, Ma Source Type: research
