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Condition: Hughes Syndrome
Drug: Aspirin
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Total 646 results found since Jan 2013.
Geriatric patient with neurological symptoms and prolonged aPTT
Inn Med (Heidelb). 2023 Sep 20. doi: 10.1007/s00108-023-01581-3. Online ahead of print.ABSTRACTA 73-year-old man with dementia was referred to our clinic with hypernatremia and volume depletion. New-onset neurogenic dysphagia was likely the reason for both. The patient had chronic embolic strokes on the computed tomography (CT) images. Documentation from previous hospitalizations in different hospitals revealed a repeatedly prolonged activated partial thromboplastin time (aPTT); 5 years prior, antiphospholipid antibody syndrome had already been suspected, but the necessary workup was never completed. We diagnosed the patie...
Source: Hamostaseologie - September 20, 2023 Category: Hematology Authors: Aisuluu Atakanova Anne Heiligers Martin Kirschner Cornelius Bollheimer Susanne Fleig Source Type: research
Recurrent MiscarriageGreen-top Guideline No. 17
BJOG. 2023 Jun 19. doi: 10.1111/1471-0528.17515. Online ahead of print.ABSTRACTIn this guideline, recurrent miscarriage has been defined as three or more first trimester miscarriages. However, clinicians are encouraged to use their clinical discretion to recommend extensive evaluation after two first trimester miscarriages, if there is a suspicion that the miscarriages are of pathological and not of sporadic nature. Women with recurrent miscarriage should be offered testing for acquired thrombophilia, particularly for lupus anticoagulant and anticardiolipin antibodies, prior to pregnancy. [Grade C] Women with second trimes...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - June 19, 2023 Category: OBGYN Authors: Lesley Regan Rajendra Rai Sotirios Saravelos Tin-Chiu Li Royal College of Obstetricians and Gynaecologists Source Type: research
Acute coronary syndromes in Antiphospholipid syndrome-above suspicion: a systematic review
In this study, we conducted a systematic review of the literature utilizing the Pubmed platform, in order to acquire clinical information about acute coronary syndromes in patients with APS. The obtained articles were reviewed in order to register the clinical characteristics, the rate of occurrence, the prognosis and the therapeutic approach of these patients. APS should be considered in young patients with acute myocardial infarction, even in patients with normal coronary arteries. The pharmaceutical approach is mainly based on the vitamin K antagonists, and in certain occasions aspirin, without any definite guidelines o...
Source: Atherosclerosis - November 19, 2022 Category: Cardiology Authors: Nevras Vasileios Milaras Nikias Katsioulis Christos Sotiriou Zoi Tsalamandris Sotirios Gkounti Georgia Sideris Skevos Source Type: research
Cardiovascular disease risk in antiphospholipid syndrome: Thrombo-inflammation and atherothrombosis
J Autoimmun. 2022 Mar 2;128:102813. doi: 10.1016/j.jaut.2022.102813. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is an autoimmune disorder characterized by the presence of antiphospholipid antibodies (aPL) (lupus anticoagulant, anticardiolipin antibodies and anti-beta2glycoprotein I (anti-β2GPI) antibodies) and a plethora of macro- and micro-vascular manifestations, affecting predominantly young adults. Cardiovascular events are the leading causes of morbidity and mortality in APS. APL-mediated thrombo-inflammation and atherothrombosis are emerging pathogenetic mechanisms of cardiovascular disease (CVD) ...
Source: Journal of Autoimmunity - March 5, 2022 Category: Allergy & Immunology Authors: Maria G Tektonidou Source Type: research
Clinical and therapeutic value of the adjusted Global Antiphospholipid Syndrome Score in primary obstetric antiphospholipid syndrome
CONCLUSION: aGAPSS appears to be useful in predicting the occurrence of a first thrombotic event in POAPS patients, and these stratification of patients could be helpful in selecting patients who would benefit from thromboprophylaxis with LDA.PMID:35157809 | DOI:10.1177/09612033221078223
Source: Lupus - February 14, 2022 Category: Rheumatology Authors: Sebasti án Udry Stephanie Morales Per éz Cristina Belizna Federico Aranda Enrique Esteve-Valverde Silvia Per és Wingeyer Diego S Fern ández-Romero Jos é O Latino Gabriela de Larra ñaga Jaume Alijotas-Reig Source Type: research
