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Concurrency of Early-Age Exposure to Chinese Famine and Diabetes Increases Recurrence of Ischemic Stroke
Conclusions: Concurrency of early-age famine exposure and diabetes mellitus was associated with a higher risk of stroke recurrence within 12 months, and adherence to evidence-based KPI did not reduce the risk significantly.
Source: Frontiers in Neurology - January 20, 2021 Category: Neurology Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Association of hemoglobin glycation index with outcomes of acute ischemic stroke in type 2 diabetic patients.
Conclusion Both low HGI and high HGI was associated with an increased risk of poor prognosis in diabetic patients with ischemic stroke, compared with moderate HGI. PMID: 29560815 [PubMed - as supplied by publisher]
Source: Neurological Research - March 23, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Prospective Study of Fasting Blood Glucose and Intracerebral Hemorrhagic Risk Clinical Sciences
The objective of the current study was to examine the potential impact of long-term fasting blood glucose concentration on subsequent risk of ICH.Methods—This prospective study included 96 110 participants of the Kailuan study, living in Kailuan community, Tangshan city, China, who were free of cardiovascular diseases and cancer at baseline (2006). Fasting blood glucose concentration was measured in 2006, 2008, 2010, and 2012. Updated cumulative average fasting blood glucose concentration was used as primary exposure of the current study. Incident ICH from 2006 to 2015 was confirmed by review of medical records.Results...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Cheng Jin, Guohong Li, Kathryn M. Rexrode, Mahmut E. Gurol, Xiaodong Yuan, Ying Hui, Chunyu Ruan, Anand Vaidya, Yanxiu Wang, Shouling Wu, Xiang Gao Tags: Cardiovascular Disease, Diabetes, Type 2, Epidemiology, Risk Factors, Intracranial Hemorrhage Original Contributions Source Type: research

Pancreatic {beta}-Cell Function and Prognosis of Nondiabetic Patients With Ischemic Stroke Clinical Sciences
Conclusions—In this large-scale registry, β-cell dysfunction was associated with an increased risk of 12-month poor prognosis in nondiabetic patients with ischemic stroke.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Yuesong Pan, Weiqi Chen, Jing Jing, Huaguang Zheng, Qian Jia, Hao Li, Xingquan Zhao, Liping Liu, Yongjun Wang, Yan He, Yilong Wang Tags: Diabetes, Type 2, Secondary Prevention, Ischemic Stroke Original Contributions Source Type: research