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Condition: Chronic Kidney Disease
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Total 1632 results found since Jan 2013.

Effect of High-Dose Atorvastatin on Renal Function in Subjects With Stroke or Transient Ischemic Attack in the SPARCL Trial Clinical Sciences
Conclusions— This post hoc analysis suggests that atorvastatin treatment may improve renal function in patients with prior stroke or transient ischemic attack with and without chronic kidney disease, and that atorvastatin treatment may prevent eGFR decline in patients with stroke and diabetes mellitus. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00147602.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Amarenco, P., Callahan, A., Campese, V. M., Goldstein, L. B., Hennerici, M. G., Messig, M., Sillesen, H., Welch, K. M. A., Wilson, D. J., Zivin, J. A. Tags: Lipids, Secondary prevention, Cerebrovascular disease/stroke Clinical Sciences Source Type: research

Importance of Considering Competing Risks in Time-to-Event Analyses: Application to Stroke Risk in a Retrospective Cohort Study of Elderly Patients With Atrial Fibrillation Original Articles
Conclusions: The incidence of death without stroke was 9-fold higher than that of stroke, leading to biased estimates of stroke risk with traditional time-to-event methods. Statistical methods that appropriately account for competing risks should be used to mitigate this bias.
Source: Circulation: Cardiovascular Quality and Outcomes - July 11, 2018 Category: Cardiology Authors: Abdel-Qadir, H., Fang, J., Lee, D. S., Tu, J. V., Amir, E., Austin, P. C., Anderson, G. M. Tags: Atrial Fibrillation, Epidemiology, Primary Prevention, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Proteinuria, but Not eGFR, Predicts Stroke Risk in Chronic Kidney Disease: Chronic Renal Insufficiency Cohort Study Clinical Sciences
Conclusions— Proteinuria and albuminuria are better predictors of stroke risk in patients with chronic kidney disease than estimated glomerular filtration rate. The impact of therapies targeting proteinuria/albuminuria in individuals with chronic kidney disease on stroke prevention warrants further investigation.
Source: Stroke - July 27, 2015 Category: Neurology Authors: Sandsmark, D. K., Messe, S. R., Zhang, X., Roy, J., Nessel, L., Lee Hamm, L., He, J., Horwitz, E. J., Jaar, B. G., Kallem, R. R., Kusek, J. W., Mohler, E. R., Porter, A., Seliger, S. L., Sozio, S. M., Townsend, R. R., Feldman, H. I., Kasner, S. E., CRIC S Tags: Clinical Sciences Source Type: research

MELAS Syndrome: How Stroke-like are the Stroke episodes? (P1.255)
Conclusions:Patients with MELAS syndrome may present with recurrent strokes in the arterial territory rather than SLEs. Clinicians should entertain the possibility of a mitochondrial disease in young patients with cryptogenic stroke and pursue appropriate diagnostic evaluations and treatment.Disclosure: Dr. Liaw has nothing to disclose. Dr. Lewis has nothing to disclose. Dr. Saini has nothing to disclose. Dr. Gultekin has nothing to disclose. Dr. Koch has nothing to disclose. Dr. Asdaghi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Liaw, N., Lewis, R., Saini, V., Gultekin, S. H., Koch, S., Asdaghi, N. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Prospective association between {beta}2-microglobulin levels and ischemic stroke risk among women
Conclusion: High levels of B2M were associated with an increased risk of ischemic stroke among women.
Source: Neurology - June 5, 2017 Category: Neurology Authors: Rist, P. M., Jimenez, M. C., Rexrode, K. M. Tags: All Cerebrovascular disease/Stroke, Case control studies, Risk factors in epidemiology ARTICLE Source Type: research

Clinical Features and Functional Outcome of Stroke After Transient Ischemic Attack
Conclusions: Atherothrombotic stroke with concomitant vascular risk factors were more frequent in the stroke patients with than without previous TIA. Antithrombotic therapy was conducted only in one-third of the patients even after TIA. The stroke patients with history of TIA were at great risk of disabling stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 17, 2011 Category: Neurology Authors: Takao Hoshino, Satoko Mizuno, Satoru Shimizu, Shinichiro Uchiyama Tags: Original Articles Source Type: research

Plasma FGF23 and the risk of stroke: The Northern Manhattan Study (NOMAS)
Conclusions: Elevated FGF23 was a risk factor for overall stroke and ICH events, in particular in a racially and ethnically diverse urban community, independent of chronic kidney disease.
Source: Neurology - May 12, 2014 Category: Neurology Authors: Wright, C. B., Dong, C., Stark, M., Silverberg, S., Rundek, T., Elkind, M. S. V., Sacco, R. L., Mendez, A., Wolf, M. Tags: All Cerebrovascular disease/Stroke, Cohort studies, Incidence studies, Intracerebral hemorrhage ARTICLE Source Type: research

Gender Difference in Stroke Case Fatality: An Integrated Study of Hospitalization and Mortality
Conclusions: Among persons hospitalized with a stroke in Nebraska between 2005 and 2009, the crude case fatality rate was 50% higher in women. However, after accounting for age and other variables, adjusted mortality rates were essentially the same for men and women.
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2011 Category: Neurology Authors: David DeVries, Ying Zhang, Ming Qu, Jihyun Ma, Ge Lin Tags: Original Articles Source Type: research

Comparison of Associations of Outcomes After Stroke With Estimated GFR Using Chinese Modifications of the MDRD Study and CKD-EPI Creatinine Equations: Results From the China National Stroke Registry
Background: The CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) creatinine equation estimates glomerular filtration rate (GFR) more precisely than the MDRD (Modification of Diet in Renal Disease) Study equation. The risk implications of this equation have been compared with the MDRD Study equation in different demographic and clinical characteristics. However, whether a Chinese modification of this equation performs better than a Chinese modification of the MDRD Study equation in risk prediction in Chinese patients with stroke is unknown.Study Design: Prospective cohort study, China National Stroke Registry.Set...
Source: American Journal of Kidney Diseases - October 7, 2013 Category: Urology & Nephrology Authors: Xianwei Wang, Yang Luo, Yilong Wang, Chunxue Wang, Xingquan Zhao, David Wang, Liping Liu, Gaifen Liu, Yongjun Wang, China National Stroke Registry Investigators Tags: Pathogenesis and Treatment of Kidney Disease Source Type: research

Increased risk of stroke in patients with chronic kidney disease after recurrent hypoglycemia
Conclusions: CKD was associated with a higher risk of stroke and mortality in patients with hypoglycemia. Recurrent hypoglycemia considerably increased the risk of stroke and overall mortality in patients with CKD regardless of whether they had diabetes. These results suggest that hypoglycemia has a crucial role in stroke and death in patients with CKD.
Source: Neurology - August 18, 2014 Category: Neurology Authors: Yu, T.-M., Lin, C.-L., Chang, S.-N., Sung, F.-C., Kao, C.-H. Tags: Prognosis, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Risk of Thromboembolic Events in Atrial Fibrillation With Chronic Kidney Disease Clinical Sciences
Conclusions— Impaired renal function is an independent predictor of stroke or systemic embolism in patients with nonvalvular AF. Consideration of renal function may improve stroke risk stratification in patients with AF.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Zeng, W.-T., Sun, X.-T., Tang, K., Mei, W.-Y., Liu, L.-J., Xu, Q., Cheng, Y.-J. Tags: Embolic stroke Clinical Sciences Source Type: research

Comment: The benefits of antiplatelets on stroke-- More arguments to keep patients adherent
The role of antiplatelet agents in stroke prevention is well documented, especially for secondary prevention, but many patients with no previous stroke but with other risk factors (high cardiovascular risk, women with diabetes mellitus, chronic kidney disease, peripheral artery disease, or asymptomatic carotid stenosis) can also benefit. The findings of Jung et al.1 are therefore clinically relevant and can be used to reassure patients that even if antiplatelet agents fail to prevent stroke, they can mitigate its severity. Although it is an observational study, a randomized trial to test the effect of antiplatelet agents o...
Source: Neurology - March 16, 2015 Category: Neurology Authors: Niewada, M. Tags: MRI, All Cerebrovascular disease/Stroke, Class II, Case control studies, Natural history studies (prognosis) ARTICLE Source Type: research

Race Does Not Predict Discharge Functional Status in Acute Ischemic Stroke Patients with Renal Impairment after Systemic tPA (P7.142)
Conclusions: Our data are consistent with previous studies that renal impairment is a predictor of poor discharge outcome. Although limited by relatively small numbers, our analysis did not demonstrate AA race predicted poor discharge functional status.Disclosure: Dr. Sands has nothing to disclose. Dr. Kumar has nothing to disclose. Dr. Shiue has nothing to disclose. Dr. Bavarsad Shahripour has nothing to disclose. Dr. Alexandrov has received personal compensation for activities with Genentech, Inc.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Sands, K., Kumar, G., Shiue, H., Bavarsad Shahripour, R., Alexandrov, A. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Neurons Over Nephrons Clinical Sciences
Background and Purpose—Because of the perceived risk of contrast-induced acute kidney injury (AKI), many centers require pre-imaging serum creatinine levels, potentially delaying care. We performed a systematic review and meta-analysis evaluating AKI rates in patients with acute ischemic stroke receiving computed tomographic angiography (CTA) and computed tomographic perfusion (CTP).Methods—We searched MEDLINE, EMBASE, and the Web of Science through December 2016 for studies reporting on AKI in patients with acute ischemic stroke receiving CTA/CTP. Using a random-effects model, estimates were pooled across studies. Out...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Waleed Brinjikji, Andrew M. Demchuk, Mohammad H. Murad, Alejandro A. Rabinstein, Robert J. McDonald, Jennifer S. McDonald, David F. Kallmes Tags: Imaging, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Acute and Chronic Kidney Dysfunction and Outcome After Stroke Thrombectomy
AbstractData on the impact of kidney dysfunction on outcome in patients with stroke due to large vessel occlusion are scarce. The few available studies are limited by only considering single kidney parameters measured at one time point. We thus investigated the influence of both chronic kidney disease (CKD) and acute kidney injury (AKI) on outcome after mechanical thrombectomy. We included consecutive patients with anterior circulation large vessel occlusion stroke receiving mechanical thrombectomy at our center over an 8-year period. We extracted clinical data from a prospective registry and investigated kidney serum para...
Source: Translational Stroke Research - January 4, 2021 Category: Neurology Source Type: research