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Condition: Bleeding
Procedure: Coronary Artery Bypass Graft

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Total 448 results found since Jan 2013.

Morbidity But Not Mortality Is Decreased After Off-Pump Coronary Artery Bypass Surgery.
CONCLUSIONS: Off-pump CABG was associated with less morbidity, shorter length of stay, and similar mortality compared with on-pump procedures, suggesting that it can be a safe and effective alternative to standard on-pump CABG. However, the limited use of off-pump CABG in this multicenter analysis may restrict the generalizability of these results, and realistically defines the limited degree of acceptance of this technique in a real-world environment. PMID: 24200395 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - November 5, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Brewer R, Theurer PF, Cogan CM, Bell GF, Prager RL, Paone G, Membership of the Michigan Society of Thoracic and Cardiovascular Surgeons Tags: Ann Thorac Surg Source Type: research

Association Between Intraprocedural Thrombotic Events and Adverse Outcomes After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction (a Harmonizing Outcomes With RevasculariZatiON and Stents in Acute Myocardial Infarction HORIZONS-AMI Substudy)
The present study sought to determine the extent to which adverse angiographic events encountered during percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI) are associated with adverse clinical outcomes. Patients with STEMI represent a cohort at particularly high risk of intraprocedural thrombotic events (IPTEs). The overall frequency and implications of IPTEs occurring in patients with STEMI have not been systematically quantified in previous studies. A total of 3,163 patients undergoing primary percutaneous coronary intervention with stent implantation for STEMI in the Harmonizing Ou...
Source: The American Journal of Cardiology - October 28, 2013 Category: Cardiology Authors: Ajay J. Kirtane, Prabhdeep Sandhu, Roxana Mehran, Margaret McEntegart, Ecaterina Cristea, Sorin J. Brener, Ke Xu, Martin Fahy, Philippe Généreux, Jeffrey D. Wessler, Gregg W. Stone Tags: Coronary Artery Disease Source Type: research

Outcomes of surgical aortic valve replacement in moderate risk patients: Implications for determination of equipoise in the transcatheter era
Objective: To determine the contemporary outcomes of surgical aortic valve replacement (SAVR) in a moderate surgical risk population.Methods: We studied 502 consecutive adults who had undergone isolated SAVR from January 2002 to June 2011 for severe aortic valve stenosis with a Society of Thoracic Surgery predicted risk of mortality of 4% to 8%. We included concomitant coronary artery bypass and aortic annular enlargement but not other concomitant procedures. The updated Valve Academic Research Consortium definitions were used, as appropriate.Results: The median age was 80 years (range, 49-96), 323 (64.3%) had New York Hea...
Source: The Journal of Thoracic and Cardiovascular Surgery - October 7, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Sebastian A. Iturra, Rakesh M. Suri, Kevin L. Greason, John M. Stulak, Harold M. Burkhart, Joseph A. Dearani, Hartzell V. Schaff Tags: Acquired Cardiovascular Disease Source Type: research

Early clinical and angiographic outcomes after robotic-assisted coronary artery bypass surgery
Objective: Robotic-assisted coronary artery bypass grafting has emerged as an alternative to traditional coronary artery bypass grafting or percutaneous intervention for patients with coronary artery disease. However, the safety and efficacy of this minimally invasive procedure have not been established in large series.Methods: From October 2009 to September 2012, 307 consecutive robotic-assisted coronary artery bypass grafting procedures were performed at a single US institution by 2 surgeons. Isolated, off-pump, left internal thoracic artery to left anterior descending coronary artery grafting was planned via a 3- to 4...
Source: The Journal of Thoracic and Cardiovascular Surgery - October 29, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Michael E. Halkos, Henry A. Liberman, Chandan Devireddy, Patrick Walker, Aloke V. Finn, Wissam Jaber, Robert A. Guyton, John D. Puskas Tags: Acquired Cardiovascular Disease Source Type: research

Intra-aortic balloon counterpulsation - Basic principles and clinical evidence.
Abstract Intra-aortic balloon pump (IABP) counterpulsation has been the most widely used left ventricular assist device for nearly five decades. Due to diastolic inflation and systolic deflation, coronary blood flow is increased and afterload decreased translating into augmentation of oxygen supply and lowering of oxygen demand. However, IABP may be associated with serious complications, including major bleeding, stroke, local and systemic infections and vascular complications. These might counterbalance the potential beneficial hemodynamic effects. In clinical routine, IABP is mainly used in high-risk patients wi...
Source: Vascular Pharmacology - December 28, 2013 Category: Drugs & Pharmacology Authors: de Waha S, Desch S, Eitel I, Fuernau G, Lurz P, Sandri M, Schuler G, Thiele H Tags: Vascul Pharmacol Source Type: research

Efficacy of Prophylactic Intra‐Aortic Balloon Pump Therapy in Chronic Heart Failure Patients Undergoing Cardiac Surgery
This study investigated the efficacy of prophylactic intraoperative intra‐aortic balloon pump (IABP) usage in chronic heart failure patients with severely reduced left ventricular function undergoing elective cardiac surgery. Between January 2008 and December 2012, 107 patients with severely reduced left ventricular ejection fraction (LVEF <35%) received prophylactic intraoperative IABP implantation during open‐heart surgery. Surgical procedures performed were isolated coronary artery bypass grafting (CABG) in 35 patients (32.7%), aortic valve replacement in 12 (11.2%), mitral valve repair or replacement in 15 (14.0...
Source: Artificial Organs - February 1, 2014 Category: Transplant Surgery Authors: Yalin Yildirim, Simon Pecha, Mathias Kubik, Yousuf Alassar, Tobias Deuse, Samer Hakmi, Hermann Reichenspurner Tags: Thoughts and Progress Source Type: research

Procedural Volume and Outcomes With Radial or Femoral Access for Coronary Angiography and Intervention
ConclusionsProcedural volume and expertise are important, particularly for radial percutaneous coronary intervention. (A Trial of Trans-radial Versus Trans-femoral Percutaneous Coronary Intervention [PCI] Access Site Approach in Patients With Unstable Angina or Myocardial Infarction Managed With an Invasive Strategy [RIVAL]; NCT01014273)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - March 10, 2014 Category: Cardiology Source Type: research

Can the temporary use of right ventricular assist devices bridge patients with acute right ventricular failure after cardiac surgery to recovery?
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: Can the temporary use of right ventricular assist devices (RVADs) bridge patients to recovery who suffer acute right ventricular failure after cardiac surgery? More than 183 papers were found using the reported search, of which 13 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. Indications for surgical intervention included coronary artery bypas...
Source: Interactive CardioVascular and Thoracic Surgery - March 17, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Lang, S. A., O'Neill, B., Waterworth, P., Bilal, H. Tags: Adult Cardiac Source Type: research

Reprint of "Intra-aortic balloon counterpulsation - Basic principles and clinical evidence"
Abstract Intra-aortic balloon pump (IABP) counterpulsation has been the most widely used left ventricular assist device for nearly five decades. Due to diastolic inflation and systolic deflation, coronary blood flow is increased and afterload decreased translating into augmentation of oxygen supply and lowering of oxygen demand. However, IABP may be associated with serious complications, including major bleeding, stroke, local and systemic infections and vascular complications. These might counterbalance the potential beneficial hemodynamic effects. In clinical routine, IABP is mainly used in high-risk patients wi...
Source: Vascular Pharmacology - March 18, 2014 Category: Drugs & Pharmacology Authors: de Waha S, Desch S, Eitel I, Fuernau G, Lurz P, Sandri M, Schuler G, Thiele H Tags: Vascul Pharmacol Source Type: research

Ascending-to-Descending Aoritc Bypass: A Simple Solution to a Complex Problem.
CONCLUSIONS: The ascending-to-descending aortic bypass can be performed with low morbidity and mortality. It is an effective solution to complex aortic coarctation and represents a safe single-stage approach for patients with concomitant cardiac pathology. PMID: 24725830 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - April 8, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Said SM, Burkhart HM, Dearani JA, Connolly HM, Schaff HV Tags: Ann Thorac Surg Source Type: research

Efficacy and Safety of Adjusted-Dose Prasugrel Compared With Clopidogrel in Japanese Patients With Acute Coronary Syndrome.
Conclusions: Prasugrel 20/3.75mg was associated with a low incidence of ischemic events, similar to the results of TRITON-TIMI 38, and with a low risk of clinically serious bleeding in Japanese ACS patients. PMID: 24759796 [PubMed - as supplied by publisher]
Source: Circulation Journal - April 22, 2014 Category: Cardiology Authors: Saito S, Isshiki T, Kimura T, Ogawa H, Yokoi H, Nanto S, Takayama M, Kitagawa K, Nishikawa M, Miyazaki S, Nakamura M Tags: Circ J Source Type: research

Impact of Dual Antiplatelet Therapy on Outcomes Among Aspirin-Resistant Patients Following Coronary Artery Bypass Grafting
This study was designed to define the impact of dual antiplatelet therapy (dAPT) on clinical outcomes among aspirin-resistant patients who underwent coronary artery surgery. We randomly assigned 219 aspirin-resistant patients according to multiple electrode aggregometry to receive clopidogrel (75 mg) plus aspirin (300 mg) or aspirin-monotherapy (300 mg). The primary end point was a composite outcome of all-cause death, nonfatal myocardial infarction, stroke, or cardiovascular hospitalization assessed at 6 months postoperatively. The primary end point occurred in 6% of patients assigned to dAPT and 10% of patients rando...
Source: The American Journal of Cardiology - March 3, 2014 Category: Cardiology Authors: Hrvoje Gasparovic, Mate Petricevic, Tomislav Kopjar, Zeljko Djuric, Lucija Svetina, Bojan Biocina Tags: Coronary Artery Disease Source Type: research

Perioperative outcomes after on- and off-pump coronary artery bypass grafting.
Abstract Although numerous reports describe the results of off-pump coronary artery bypass grafting (CABG) at specialized centers and in select patient populations, it remains unclear how off-pump CABG affects real-world patient outcomes. We conducted a large, multicenter observational cohort study of perioperative death and morbidity in on-pump (ON) versus off-pump (OFF) CABG. We reviewed Veterans Affairs Surgical Quality Improvement Program data for all patients (N=65,097) who underwent isolated CABG from October 1997 through April 2011 (intention-to-treat data were available from 2005 onward). The primary outco...
Source: Texas Heart Institute Journal - April 1, 2014 Category: Cardiology Authors: Bakaeen FG, Chu D, Kelly RF, Holman WL, Jessen ME, Ward HB Tags: Tex Heart Inst J Source Type: research

Characteristics, treatment and one-year outcomes of patients with acute coronary syndrome in a tertiary hospital in India.
CONCLUSIONS: ACS population was older than previously described in India. Evidence-based pharmacotherapy and interventions, and outcomes were comparable to the developed nations. PMID: 24814108 [PubMed - in process]
Source: Indian Heart J - March 1, 2014 Category: Cardiology Authors: Isezuo S, Subban V, Krishnamoorthy J, Pandurangi UM, Janakiraman E, Kalidoss L, Sankardas MA Tags: Indian Heart J Source Type: research

Optimal Conduit for Diabetic Patients: Propensity Analysis of Radial and Right Internal Thoracic Arteries.
CONCLUSIONS: In diabetic patients undergoing multivessel revascularization with either RA or RITA grafts to the circumflex coronary, long-term survival is similar. However, RA patients experienced significantly fewer respiratory or sternal wound adverse events. The RA is the preferred conduit to extend to more diabetic patients the recognized survival benefit of a multiple arterial graft strategy. PMID: 24878172 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - May 28, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Hoffman DM, Dimitrova KR, Lucido DJ, Dincheva GR, Geller CM, Balaram SK, Ko W, Swistel DG, Tranbaugh RF Tags: Ann Thorac Surg Source Type: research