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Specialty: Cardiology
Condition: Cardiomyopathy
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Total 533 results found since Jan 2013.
Glucose lowering does not necessarily reduce cardiovascular risk in type 2 diabetes
World J Cardiol. 2022 Apr 26;14(4):266-270. doi: 10.4330/wjc.v14.i4.266.ABSTRACTDiabetes mellitus (DM) is a health condition characterized by glucose dysregulation and affects millions of people worldwide. The presentation of heart failure in diabetic cardiomyopathy extends over a wide phenotypic spectrum, commencing from asymptomatic, subclinical structural abnormalities to severely symptomatic biventricular dysfunction with increased mortality risk. Similarly, the spectrum of systolic dysfunction in diabetic-induced heart failure is diverse. DM leads also to cardiac electrical remodeling reacting on various targets. Dipe...
Source: World Journal of Cardiology - May 18, 2022 Category: Cardiology Authors: Angeliki Bourazana Grigorios Giamouzis John Skoularigis Filippos Triposkiadis Andrew Xanthopoulos Source Type: research
En-571-02 screening for putative pathogenic variants in dilated cardiomyopathy genes identifies early disease and predicts mortality
Dilated cardiomyopathy (DCM) can present with the sentinel event of sudden cardiac death, as well as heart failure, ECG abnormalities, atrial fibrillation or stroke. Data are limited regarding genetic screening and the mortality associated with DCM in a general population.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Ravi Shah, Babken Asatryan, Ghaith Sharaf Dabbagh, Mohammed Khanji, Stefan van Duijvenboden, Daniele Muser, Andrew Paul Landstrom, Christopher Semsarian, Virend Somers, Patricia B. Munroe, Anwar A. Chahal Source Type: research
Cannabinoid receptor 2 activation alleviates diabetes-induced cardiac dysfunction, inflammation, oxidative stress, and fibrosis
In this study, we explored the role of CB2R signaling in myocardial dysfunction, oxidative/nitrative stress, inflammation, cell death, remodeling, and fibrosis associated with diabetic cardiomyopathy in type 1 diabetic mice. Control human heart left ventricles and atrial appendages, similarly to mouse hearts, had negligible CB2R expression determine by RNA sequencing or real-time RT-PCR. Diabetic cardiomyopathy was characterized by impaired diastolic and systolic cardiac function, enhanced myocardial CB2R expression, oxidative/nitrative stress, and pro-inflammatory response (tumor necrosis factor-α, interleukin-1β, intra...
Source: Atherosclerosis - April 23, 2022 Category: Cardiology Authors: Mohanraj Rajesh Partha Mukhopadhyay S ándor Bátkai Muhammad Arif Zolt án V Varga Csaba M átyás Janos Paloczi Andrea Lehocki Gy örgy Haskó Pal Pacher Source Type: research
COVID-19-induced cardiovascular damage differs from other prevalent viruses
Cardiol Plus. 2021 Oct 1;6(4):231-245. doi: 10.4103/2470-7511.334401. Epub 2021 Dec 30.ABSTRACTViral infections persist globally, among all ages, gender, and ethnicity. Of particular importance is COVID-19, associated with asymptomatic to severe symptoms, including complications/mortality. Cardiovascular disease (CVD) involves heart and blood vessel disorders including coronary heart disease, cerebrovascular disease, peripheral artery disease, thrombosis, and more. CVD associated with severe COVID-19 includes heart failure, coronary artery disease, cardiomyopathy, hypertension, and cerebrovascular disease/stroke. Data were...
Source: Atherosclerosis - April 4, 2022 Category: Cardiology Authors: Rachel S Parise Sindhu Ramesh Manoj Govindarajulu Amir Ajoolabady Timothy Moore Muralikrishnan Dhanasekaran Source Type: research
Tafamidis Reduces The Decline In Longitudinal Strain And Stroke Volume In Patients With Transthyretin Amyloid Cardiomyopathy
Left ventricular (LV) longitudinal strain and stroke volume are significant predictors of mortality in patients with transthyretin amyloid cardiomyopathy (ATTR-CM). In the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT), tafamidis significantly reduced mortality and CV-related hospitalizations. Further analysis of changes in echocardiographic measures in ATTR-ACT may provide additional insight into the efficacy of tafamidis.
Source: Journal of Cardiac Failure - April 1, 2022 Category: Cardiology Authors: Perry Elliott, Allan L. Klein, Fabio Fernandes, Balarama Gundapaneni, Marla B. Sultan, Sanjiv J. Shah Tags: 256 Source Type: research
Longitudinal Observational Study of Cardiac Outcome Risk Factor Prediction in Children, Adolescents, and Adults with Barth Syndrome
AbstractBarth Syndrome (BTHS) is an X-linked mitochondrial cardioskeletal myopathy caused by defects inTAFAZZIN, a gene responsible for cardiolipin remodeling. Altered mitochondrial levels of cardiolipin lead to cardiomyopathy (CM), muscle weakness, exercise intolerance, and mortality. Cardiac risk factors predicting outcome are unknown. Therefore, we conducted a longitudinal observational study to determine risk factors for outcome in BTHS. Subjects with minimum two evaluations (or one followed by death or transplant) were included. Cardiac size, function, and QTc data were measured by echocardiography and electrocardiogr...
Source: Pediatric Cardiology - March 3, 2022 Category: Cardiology Source Type: research
Functional and hemodynamic result with the PASCAL Ace percutaneous mitral valve repair: a single-center experience
CONCLUSIONS: PASCAL Ace is safe and effective in treating MR, resulting in a sustained MR reduction, a reverse cardiac remodelling, improvement of exercise capacity, quality of life, NT-proBNP levels and hemodynamics at follow-up.PMID:35231607 | DOI:10.1016/j.hjc.2022.02.004
Source: Hellenic Journal of Cardiology - March 1, 2022 Category: Cardiology Authors: Sebastian Barth Martina B Hautmann Christian Munoz-Perez Sebastian Kerber Jan Kikec Michael Zacher Borek Foldyna Lukas Lehmkuhl Philipp Halbfass Ulrich L üsebrink Karsten Hamm Source Type: research
