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Cancer: Lung Cancer
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Total 37236 results found since Jan 2013.
LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis
CONCLUSIONS: LINC00668 acted as an oncogene in NSCLC progression through miR-518c-3p/TRIP4 axis. Our study disclosed a new mechanism of LINC00668 functioned in NSCLC and may give a deeper insight of the targeted therapy of NSCLC in the future.PMID:37718780 | DOI:10.3233/CBM-230154
Source: Cancer Biomarkers : Section A of Disease Markers - September 18, 2023 Category: Cancer & Oncology Authors: Zhibin Lu Zhichao Xiao Qi Wang Chunfeng Pan Yang Xia Weibing Wu Liang Chen Source Type: research
RNF152 Suppresses Fatty Acid Oxidation and Metastasis of Lung Adenocarcinoma by Inhibiting IRAK1-Mediated AKR1B10 Expression
This study aimed to identify the role of ring finger protein 152 (RNF152) in LUAD. RNF152 was down-regulated in LUAD, and low RNF152 expression correlated with a poor prognosis in LUAD patients. RNF152 overexpression inhibited the proliferation and malignant phenotype of LUAD cells, whereas RNF152 knockdown exerted an opposite effect. Tumor cells overexpressing RNF152 showed less fatty acid oxidation compared with control cells, whereas RNF152 knockdown induced fatty acid uptake and oxidation. Further analysis revealed the binding reaction between RNF152 and interleukin-1 receptor-associated kinase 1 (IRAK1). RNF152 reduce...
Source: Am J Pathol - September 17, 2023 Category: Pathology Authors: Dengyan Zhu Yunfei Nie Yang Zhao Xiaoming Chen Zhichang Yang Yang Yang Source Type: research
Process improvement in lymphadenectomy for lung cancer: The wave of the future?
Ann Thorac Surg. 2023 Sep 15:S0003-4975(23)00958-X. doi: 10.1016/j.athoracsur.2023.09.007. Online ahead of print.NO ABSTRACTPMID:37717886 | DOI:10.1016/j.athoracsur.2023.09.007
Source: The Annals of Thoracic Surgery - September 17, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Valerie W Rusch Source Type: research
RNF152 Suppresses Fatty Acid Oxidation and Metastasis of Lung Adenocarcinoma by Inhibiting IRAK1-Mediated AKR1B10 Expression
This study aimed to identify the role of ring finger protein 152 (RNF152) in LUAD. RNF152 was down-regulated in LUAD, and low RNF152 expression correlated with a poor prognosis in LUAD patients. RNF152 overexpression inhibited the proliferation and malignant phenotype of LUAD cells, whereas RNF152 knockdown exerted an opposite effect. Tumor cells overexpressing RNF152 showed less fatty acid oxidation compared with control cells, whereas RNF152 knockdown induced fatty acid uptake and oxidation. Further analysis revealed the binding reaction between RNF152 and interleukin-1 receptor-associated kinase 1 (IRAK1). RNF152 reduce...
Source: The American Journal of Pathology - September 17, 2023 Category: Pathology Authors: Dengyan Zhu Yunfei Nie Yang Zhao Xiaoming Chen Zhichang Yang Yang Yang Source Type: research
Process improvement in lymphadenectomy for lung cancer: The wave of the future?
Ann Thorac Surg. 2023 Sep 15:S0003-4975(23)00958-X. doi: 10.1016/j.athoracsur.2023.09.007. Online ahead of print.NO ABSTRACTPMID:37717886 | DOI:10.1016/j.athoracsur.2023.09.007
Source: The Annals of Thoracic Surgery - September 17, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Valerie W Rusch Source Type: research
RNF152 Suppresses Fatty Acid Oxidation and Metastasis of Lung Adenocarcinoma by Inhibiting IRAK1-Mediated AKR1B10 Expression
This study aimed to identify the role of ring finger protein 152 (RNF152) in LUAD. RNF152 was down-regulated in LUAD, and low RNF152 expression correlated with a poor prognosis in LUAD patients. RNF152 overexpression inhibited the proliferation and malignant phenotype of LUAD cells, whereas RNF152 knockdown exerted an opposite effect. Tumor cells overexpressing RNF152 showed less fatty acid oxidation compared with control cells, whereas RNF152 knockdown induced fatty acid uptake and oxidation. Further analysis revealed the binding reaction between RNF152 and interleukin-1 receptor-associated kinase 1 (IRAK1). RNF152 reduce...
Source: The American Journal of Pathology - September 17, 2023 Category: Pathology Authors: Dengyan Zhu Yunfei Nie Yang Zhao Xiaoming Chen Zhichang Yang Yang Yang Source Type: research
Process improvement in lymphadenectomy for lung cancer: The wave of the future?
Ann Thorac Surg. 2023 Sep 15:S0003-4975(23)00958-X. doi: 10.1016/j.athoracsur.2023.09.007. Online ahead of print.NO ABSTRACTPMID:37717886 | DOI:10.1016/j.athoracsur.2023.09.007
Source: The Annals of Thoracic Surgery - September 17, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Valerie W Rusch Source Type: research
RNF152 Suppresses Fatty Acid Oxidation and Metastasis of Lung Adenocarcinoma by Inhibiting IRAK1-Mediated AKR1B10 Expression
This study aimed to identify the role of ring finger protein 152 (RNF152) in LUAD. RNF152 was down-regulated in LUAD, and low RNF152 expression correlated with a poor prognosis in LUAD patients. RNF152 overexpression inhibited the proliferation and malignant phenotype of LUAD cells, whereas RNF152 knockdown exerted an opposite effect. Tumor cells overexpressing RNF152 showed less fatty acid oxidation compared with control cells, whereas RNF152 knockdown induced fatty acid uptake and oxidation. Further analysis revealed the binding reaction between RNF152 and interleukin-1 receptor-associated kinase 1 (IRAK1). RNF152 reduce...
Source: Am J Pathol - September 17, 2023 Category: Pathology Authors: Dengyan Zhu Yunfei Nie Yang Zhao Xiaoming Chen Zhichang Yang Yang Yang Source Type: research
Initial versus early switch to targeted therapy during first-line treatment among patients with biomarker-positive advanced or metastatic non-small cell lung cancer in the United States
CONCLUSION: In both unadjusted and adjusted analyses, there were no differences in the clinical outcomes observed among patients with a/mNSCLC in this study. This study found that initiating chemotherapy with an early switch to targeted therapy (within 56 days) of receiving biomarker positive results may be an acceptable strategy for a patient for whom immediate care is needed.PMID:37717466 | DOI:10.1016/j.ctarc.2023.100761
Source: Cell Research - September 17, 2023 Category: Cytology Authors: Lisa M Hess Patrick Peterson Tomoko Sugihara Naleen Raj Bhandari Peter M Krein Anthony Sireci Source Type: research
Concordance of ctDNA and tissue mutations in NSCLC: A meta-analysis
This article includes a total of 15 research data and collected data reports from 15 groups of NSCLC patients. The results are displayed using tissue samples as the gold standard. The Pearson correlation coefficients of sensitivity and specificity were used to calculate rho=0.044, and P=0.893. The Q-test found poor homogeneity and high heterogeneity in sensitivity and specificity among research data from various literature studies (I2>50%, P<0.1). The area under the SROC curve is 0.97 (95% CI: 0.96~0.99). The small sample subgroup has high heterogeneity, and the combined diagnosis effect size is 26[6~111], lower than...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Chengyuan Yu Yitong Han Mu Wang Peiyan Hua Yan Zhang Bin Wang Source Type: research
Effect of Yifei Qinghua Granule on the Tumor Microenvironment in Lung Cancer by Regulating the Inflammatory Pathway
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):118-124. doi: 10.14715/cmb/2023.69.8.18.ABSTRACTTo investigate the mechanism of action of inflammatory molecules regulating the tumor microenvironment and anti-tumor through Yifei Qinghua granules and phloroglucinol-containing serum intervening in the changes of tumor microenvironment in vitro in the co-culture of lung cancer cells and bone marrow cells. A549 lung adenocarcinoma cell line and ST2 bone marrow stromal cell line were selected and a transwell chamber was used to establish the co-culture system of the two kinds of cells. They were divided into normal saline, phl...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: LiHong Zhang Zhijiang Zhuang Liang Geng G E Wang Yun Cui Tongde Tian Sheng Wang Bian Shi Source Type: research
Integrated bioinformatics analysis of microarray data from non-small cell lung cancer
In conclusion, the identification of hsa-miR-21, hsa-miR-141, hsa-miR-200b hsa-miR-30a, hsa-miR-30d and hsa-miR-145 provides a new theoretical basis for understanding the development of NSCLC.PMID:37715441 | DOI:10.14715/cmb/2023.69.7.35
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Lulu Feng Wenping Cai Shan Jin Caipu Chun Chengyan Wang Luping Ma Hao Peng Xingxing Dong Jinfang Jiang Xianling Lu Lijuan Pang Source Type: research
