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Cancer: Lung Cancer
Infectious Disease: Coronavirus

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Total 226 results found since Jan 2013.

Identifying luteolin as a potential drug for treating lung adenocarcinoma with COVID-19 affection based on integration analysis of pharmacology and transcriptome
CONCLUSION: HSP90AA1 was a target gene for further designing effective drugs for LUAD patients. Luteolin was a potential drug for treating patients with both LUAD and COVID-19.PMID:37694790 | DOI:10.2174/0929867331666230908090326
Source: Current Medicinal Chemistry - September 11, 2023 Category: Chemistry Authors: Ping Peng Na Li Ni Zhang Xiangning Fu Shu Peng Yujie Zhao Bo Ai Source Type: research

Retrospective Case-Control Study of REGEN-COV (casirivimab and imdevimab) Therapy for Patients with COVID-19 and Cancer Using the United States MarketScan ® Database
Conclusion Patients with cancer treated with REGEN-COV experienced a decreased risk for hospitalization, hospitalization duration, and total COVID-19-related costs. Patients with cancer were at a higher risk of being hospitalized for COVID-19 than were those without cancer. The use of neutralizing antibody therapy may reduce the risk of severe COVID-19 infection for patients with cancer with an otherwise high risk. Future replication studies should be conducted using other databases that include Medicaid users and other insured persons for comparison and validation.PMID:37666220 | DOI:10.1159/000533614
Source: Oncology - September 4, 2023 Category: Cancer & Oncology Authors: Kazue Takemoto Source Type: research

Patient Report on the Impact of Coronavirus Disease 2019 and Living With Lung Cancer
CONCLUSIONS: An integrative patient-reported view on the impact of COVID-19 is important for adequate preparation to ensure undisrupted treatment and allocation of resources.PMID:37663676 | PMC:PMC10472288 | DOI:10.1016/j.jtocrr.2023.100549
Source: Clinical Lung Cancer - September 4, 2023 Category: Cancer & Oncology Authors: Tendai M Chihuri Upal Basu Roy Amy Moore Anne-Marie Baird Tracey L Grant Bellinda L King-Kallimanis Source Type: research

Rapid discharge after anatomic lung resection: Is ambulatory surgery for early lung cancer possible?
CONCLUSIONS: Approximately 37% of the patients underwent rapid discharge following surgery with similar readmission rate to controls. Increasing age had higher odds for non-rapid discharge; segmentectomy was likely to lead to rapid discharge. Consideration of rapid discharge minimally invasive lung resection for early-stage lung cancer can result in significant reduction in inpatient resources without adverse patient outcomes.PMID:37586584 | DOI:10.1016/j.athoracsur.2023.07.046
Source: The Annals of Thoracic Surgery - August 16, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Daniel P Dolan Maxime Visa Dan Lee Kalvin C Lung Diego Avella Patino Chitaru Kurihara Rafael Garza-Castillon David D Odell Ankit Bharat Samuel Kim Source Type: research

Radiological assessment of immunotherapy effects and immune checkpoint-related pneumonitis for lung cancer
This article reviews the complications of immunotherapy in lung cancer and illustrates various radiologic patterns of ICI-pneumonitis. Additionally, it is tried to differentiate ICI-pneumonitis from other pulmonary pathologies common to lung cancer such as radiation pneumonitis, bacterial pneumonia and coronavirus disease of 2019 (COVID-19) infection in recent months. Maybe it is challenging to distinguish radiologically but clinical presentation may help.PMID:37525480 | DOI:10.1111/jcmm.17895
Source: Molecular Medicine - August 1, 2023 Category: Molecular Biology Authors: Qiongjie Hu Shaofang Wang Li Ma Ziyan Sun Zilin Liu Shuang Deng Jianlin Zhou Source Type: research

Occupational Contributions to Respiratory Health Disparities
This article focuses on the occupational contribution to disparities in asthma, chronic obstructive pulmonary disease, silicosis, coronavirus disease 2019, and lung cancer. Because occupational exposures are largely preventable through proper workplace controls, the recognition of occupational causes of disease can provide an opportunity for interventions to bring about health equity.PMID:37517841 | DOI:10.1016/j.ccm.2023.03.016
Source: Clinical Lung Cancer - July 30, 2023 Category: Cancer & Oncology Authors: Sheiphali A Gandhi Amy Heinzerling Jennifer Flattery Kristin J Cummings Source Type: research

Proteolytic inactivation of CXCL12 in the lungs and circulation of COVID-19 patients
Cell Mol Life Sci. 2023 Jul 28;80(8):234. doi: 10.1007/s00018-023-04870-0.ABSTRACTThe human chemokine stromal cell-derived factor-1 (SDF-1) or CXCL12 is involved in several homeostatic processes and pathologies through interaction with its cognate G protein-coupled receptor CXCR4. Recent research has shown that CXCL12 is present in the lungs and circulation of patients with coronavirus disease 2019 (COVID-19). However, the question whether the detected CXCL12 is bioactive was not addressed. Indeed, the activity of CXCL12 is regulated by NH2- and COOH-terminal post-translational proteolysis, which significantly impairs its ...
Source: Cellular and Molecular Life Sciences : CMLS - July 28, 2023 Category: Cytology Authors: Seppe Cambier Fabio Beretta No ëmie Pörtner Mieke Metzemaekers Ana Carolina de Carvalho Erik Martens Janne Kaes Celine Aelbrecht Cato Jacobs Pierre Van Mol Els Wauters Philippe Meersseman Greet Hermans Rafael Elias Marques Bart Vanaudenaerde Robin Vos J Source Type: research