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Total 241 results found since Jan 2013.

Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry
Discussion Tibroviruses are highly undercharacterized rhabdoviruses with unknown pathogenic potential. All isolated tibroviruses (BAV, BHV, CPV, SWBV, and TIBV) have only been found in biting midge vectors or in various, apparently healthy non-human mammals (Cybinski et al., 1980; Standfast et al., 1984; Cybinski and Gard, 1986; Gibbs et al., 1989). The discovery of BASV, EKV-1, and EKV-2 genomes in human sera (Grard et al., 2012; Stremlau et al., 2015) suggests that at least some tibroviruses could infect humans. Because BASV was discovered in the serum of a severely ill individual, tibroviruses should be considered pote...
Source: Frontiers in Microbiology - April 25, 2019 Category: Microbiology Source Type: research

COVID-19 vaccination in mastocytosis: recommendations of the European Competence Network on Mastocytosis (ECNM) and American Initiative in Mast Cell Diseases (AIM)
J Allergy Clin Immunol Pract. 2021 Apr 5:S2213-2198(21)00386-X. doi: 10.1016/j.jaip.2021.03.041. Online ahead of print.ABSTRACTMastocytosis is a neoplasm characterized by an accumulation of mast cells in various organs and increased risk for severe anaphylaxis in patients with concomitant allergies. Covid-19 is a pandemic that is associated with a relatively high rate of severe lung disease and mortality. The mortality is particularly high in those with certain comorbidities and increases with age. Recently, several companies have developed an effective vaccination against Covid-19. Although the reported frequency of sever...
Source: Clinical Lung Cancer - April 8, 2021 Category: Cancer & Oncology Authors: Patrizia Bonadonna Knut Brockow Marek Niedoszytko Hanneke Oude Elberink Cem Akin Boguslaw Nedoszytko Joseph H Butterfield Ivan Alvarez-Twose Karl Sotlar Juliana Schwaab Mohamad Jawhar Mariana Castells Wolfgang R Sperr Olivier Hermine Jason Gotlib Roberta Source Type: research

Is your kid actin out? A series of six patients with inherited ARPC1B deficiency and review of the literature
CONCLUSION: ARPC1B deficiency has a variable and heterogeneous clinical spectrum, expanded by these cases to include keloid scars and Epstein-Barr virus chronic hepatitis. A novel deletion in exon 8 is shared by three unrelated families and might be the result of a founder effect.PMID:36708766 | DOI:10.1016/j.jaip.2022.12.045
Source: Clinical Lung Cancer - January 28, 2023 Category: Cancer & Oncology Authors: Estefan ía Vásquez-Echeverri Marco Antonio Yamazaki-Nakashimada Edna Venegas Montoya Selma Cecilia Scheffler Mendoza Lina Maria Castano-Jaramillo Edgar Alejandro Medina-Torres Maria Edith Gonz ález-Serrano Melissa Espinosa-Navarro Juan Carlos Bustamant Source Type: research

AI Cough-Monitoring Can Change the Way We Diagnose Disease
How many times do you cough a day? Do you cough more when you’re indoors or outside? Or more often after you eat? Or at night? Chances are, your cough memory might not be that accurate. But all of that information about your coughing patterns could be an untapped resource to better understand your health. Coughs may be benign ways to clear a little extra phlegm, or they could be early signs of more serious conditions such as asthma, GERD (gastroesophageal reflux disease), or even lung cancer. “In the era of precision health, it’s ironic that such a problematic symptom is simply unmeasured,” says Pet...
Source: TIME: Health - April 3, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthscienceclimate Technology Source Type: news

Emollients for preventing atopic eczema: Cost-effectiveness analysis of the BEEP trial
CONCLUSIONS: In line with effectiveness endpoints, advice given in the BEEP trial to apply daily emollient during infancy for eczema prevention in high-risk children does not appear cost-effective.PMID:37574761 | DOI:10.1111/cea.14381
Source: Clinical Lung Cancer - August 14, 2023 Category: Cancer & Oncology Authors: Tracey H Sach Stella T Lartey Charlotte Davies Joanne R Chalmers Rachel H Haines Lucy E Bradshaw Alan A Montgomery Kim S Thomas Sara J Brown Matthew J Ridd Sandra Lawton Mike J Cork Carsten Flohr Eleanor Mitchell Richard Swinden Laura Wyatt Stella Tarr Su Source Type: research

CD24: a potential new marker in differentiating malignant mesothelioma from pulmonary adenocarcinoma
Conclusions CD24 positivity can accurately discriminate MM from MLA. Prospective studies are warranted to clarify whether CD24 could integrate with other immunomarkers to facilitate the diagnosis of mesothelial malignancies.
Source: Journal of Clinical Pathology - February 21, 2013 Category: Pathology Authors: Pinato, D. J., Nya, P., Sharma, R., Mauri, F. A. Tags: Immunology (including allergy), Lung cancer (oncology), Respiratory cancer, Lung cancer (respiratory medicine) Short report Source Type: research

Lung T-cell responses to nontypeable Haemophilus influenzae in patients with chronic obstructive pulmonary disease
Conclusion: NTHi activates lung T cells in patients with COPD. This proinflammatory profibrotic response might be a key cause of inflammation in patients with COPD and has implications for treatment.
Source: Journal of Allergy and Clinical Immunology - November 12, 2012 Category: Allergy & Immunology Authors: Paul T. King, Steven Lim, Adrian Pick, James Ngui, Zdenka Prodanovic, William Downey, Cliff Choong, Anthony Kelman, Elizabeth Baranyai, Michelle Francis, Randall Moshinsky, Philip G. Bardin, Peter W. Holmes, Stephen R. Holdsworth Tags: Asthma and lower airway disease Source Type: research

Abdominal trauma and lung nodules
Introduction Splenosis represents the deposition of viable splenic tissue in a different anatomic compartment, usually following trauma. The extent of deposition is related to the severity of trauma and amount of pulp tissue released into the abdominal and pelvic cavities. Thoracic splenosis, is the deposition of splenic tissue within the thoracic cavity and occurs in about 18% of cases.1 This splenic tissue is thought to perform normal splenic functions and draws its blood supply from surrounding tissue. The condition is usually discovered incidentally, and patients are often asymptomatic males as in the case described be...
Source: Postgraduate Medical Journal - May 17, 2013 Category: Journals (General) Authors: Nazareth, D., Seshadri, N., Binukrishnan, S., Ledson, M., Walshaw, M., Mohan, K. Tags: Journalology, Immunology (including allergy), Pain (neurology), Lung cancer (oncology), Screening (oncology), Radiology, Lung cancer (respiratory medicine), Clinical diagnostic tests, Radiology (diagnostics), Ethics Images in medicine Source Type: research

Use of immunohistochemistry in the diagnosis of problematic breast lesions
This article reviews the common uses of immunohistochemistry in diagnostic breast pathology. It is important to be aware of the limitations of individual antibodies. Such problems can often be overcome by using panels of antibodies. Quality control is also essential: internal and external controls should show appropriate staining. Immunohistochemistry must be interpreted in combination with the morphology seen on H&E sections. Myoepithelial markers, such as smooth muscle actin, smooth muscle myosin heavy chain and p63, are useful for distinguishing invasive carcinoma from sclerosing lesions and ductal carcinoma in situ...
Source: Journal of Clinical Pathology - May 22, 2013 Category: Pathology Authors: Lee, A. H. S. Tags: Immunology (including allergy), Breast cancer, Skin cancer, Gynecological cancer, Lung cancer (oncology), Lung cancer (respiratory medicine), Dermatology Review Source Type: research

Aberrant anaplastic lymphoma kinase expression in high-grade pulmonary neuroendocrine carcinoma
Conclusions Thus, this aberrant expression is probably of a wild-type ALK and a potential pitfall when implementing sensitive ALK immunohistochemistry in the molecular diagnosis of lung cancer.
Source: Journal of Clinical Pathology - July 22, 2013 Category: Pathology Authors: Nakamura, H., Tsuta, K., Yoshida, A., Shibata, T., Wakai, S., Asamura, H., Furuta, K., Tsuda, H. Tags: Molecular genetics, Immunology (including allergy), Endocrine cancer, Lung cancer (oncology), Lung cancer (respiratory medicine) Original article Source Type: research

Molecular determinations of EGFR and EML4-ALK on a single slide of NSCLC tissue
Conclusions EGFR mutation analysis can be performed on the same sample previously submitted to the EML4-ALK FISH procedure.
Source: Journal of Clinical Pathology - July 22, 2013 Category: Pathology Authors: Ulivi, P., Puccetti, M., Capelli, L., Chiadini, E., Bravaccini, S., Calistri, D., Zoli, W., Amadori, D., Candoli, P. Tags: Immunology (including allergy), Lung cancer (oncology), Lung cancer (respiratory medicine) Short report Source Type: research

Lung Docs to Focus on CT Screening Debate
BARCELONA (MedPage Today) -- The city known for Gaudi and Picasso will play host to controversy over early detection of lung cancer and new data on hot topics like e-cigarettes at the European Respiratory Society meeting.
Source: MedPage Today Allergy - September 6, 2013 Category: Allergy & Immunology Source Type: news