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Early-life farm exposures and eczema among adults in the Agricultural Lung Health Study
CONCLUSIONS: In utero and childhood farming exposures are associated with decreased odds of having eczema with atopy in adults.PMID:36569583 | PMC:PMC9784317 | DOI:10.1016/j.jacig.2022.06.002
Source: Clinical Lung Cancer - December 26, 2022 Category: Cancer & Oncology Authors: Annah B Wyss Thanh T Hoang Hilde K Vindenes Julie D White Sinjini Sikdar Marie Richards Laura E Beane-Freeman Christine G Parks Mikyeong Lee David M Umbach Stephanie J London Source Type: research

Allergen immunotherapy, cancer, and immune disorders
Purpose of review The purpose of this review is to provide an update on the intriguing relationships between allergies, allergen immunotherapy, cancer, and immune disorders. Allergic diseases and cancer are increasing in incidence and prevalence and a potential relationship, or not, between these diseases have been suggested for many years. Recent findings Recent findings suggest that there may be some causative effects between certain types of cancer and allergic diseases, as described in the text. Some types of cancer may be more linked to the presence of an allergic disease, than others. However, epigenetic f...
Source: Current Opinion in Allergy and Clinical Immunology - November 4, 2022 Category: Allergy & Immunology Tags: IMMUNOTHERAPY AND NEW TREATMENTS: Edited by Giovanni Passalacqua and Robert Bush Source Type: research

Brigatinib induced photosensitivity
We present a case of blistering dermatitis suspected secondary to brigatinib.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: C. Yie, J. Rosenblum, E. Banta, S. Mawhirt Tags: M068 Source Type: research

Allergen immunotherapy, cancer, and immune disorders
Curr Opin Allergy Clin Immunol. 2022 Sep 21. doi: 10.1097/ACI.0000000000000858. Online ahead of print.ABSTRACTPURPOSE OF THE REVIEW: The purpose of this review is to provide an update on the intriguing relationships between allergies, allergen immunotherapy, cancer, and immune disorders. Allergic diseases and cancer are increasing in incidence and prevalence and a potential relationship, or not, between these diseases have been suggested for many years.RECENT FINDINGS: Recent findings suggest that there may be some causative effects between certain types of cancer and allergic diseases, as described in the text. Some types...
Source: Clinical Lung Cancer - September 27, 2022 Category: Cancer & Oncology Authors: David El-Qutob Victor Matheu Enrique Fernandez-Caldas Source Type: research

Innate Lymphoid Cells: Expression of PD-1 and Other Checkpoints in Normal and Pathological Conditions
Conclusions and Future Perspectives It is now evident that NK/ILC family plays a pivotal role in the immune defenses. Recent studies in murine and human settings demonstrated that the expression of several inhibitory checkpoints, that may be detrimental in the tumor context, is not restricted to T lymphocytes, revealing an important, yet poorly appreciated, contribution of their expression on innate immune cells. Thus, in the recent years different immunotherapy approaches, based on the blockade of inhibitory NK cell receptors, have been developed in order to unleash NK cell cytotoxicity. This is particularly important in...
Source: Frontiers in Immunology - April 25, 2019 Category: Allergy & Immunology Source Type: research

Biological monitoring of dermal and air exposure to cobalt at a Swedish hard metal production plant: does dermal exposure contribute to uptake?
ConclusionsOur data suggest that skin exposure to cobalt in the hard metal industry could affect the total uptake at the same order of magnitude as air exposure.
Source: Contact Dermatitis - July 4, 2017 Category: Dermatology Authors: Maria Klasson, Magnus Lindberg, Ing ‐Liss Bryngelsson, Helena Arvidsson, Carin Pettersson, Bente Husby, Håkan Westberg Tags: Original Article Source Type: research