Filtered By:
Cancer: Hepatocellular Carcinoma

This page shows you your search results in order of relevance. This is page number 12.

Order by Relevance | Date

Total 40824 results found since Jan 2013.

What is in the Differential Diagnosis for Green, Blue or Violet Skin Conditions?
Discussion Acrocyanosis is commonly seen in the newborn period as the baby transitions to extra-uterine life. It appears as blue-purple coloration of the distal extremities which usually improves over several hours. Blue melanocytosis is also a common normal variant of skin color. It usually is seen on the posterior surface of the body around the spine and buttocks, but can also be on the upper parts of the extremities. It is a blue-black coloration that shows a normal skin undertone when palpated. This is the second in a short case series of differential diagnoses of colored skin conditions. An introduction to dermatologi...
Source: PediatricEducation.org - May 2, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Liver Tumors in Pediatric Patients
Surg Oncol Clin N Am. 2021 Apr;30(2):253-274. doi: 10.1016/j.soc.2020.11.006.ABSTRACTThe most recent advance in the care of children diagnosed with hepatoblastoma and hepatocellular carcinoma is the Pediatric Hepatic International Tumor Trial, which opened to international enrollment in 2018. It is being conducted as a collaborative effort by the pediatric multicenter trial groups in North America, Europe, and the Far East. This international effort was catalyzed by a new unified global risk stratification system for hepatoblastoma, an international histopathologic consensus classification for pediatric liver tumors, and a...
Source: The Surgical Clinics of North America - March 12, 2021 Category: Surgery Authors: Rebecka Meyers Eiso Hiyama Piotr Czauderna Greg M Tiao Source Type: research

The Relevance of Preoperative Identification of the Adamkiewicz Artery in Posterior Mediastinal Pediatric Tumors
CONCLUSIONS: In posterior mediastinal pediatric tumors, spinal DSA is a safe and reliable method for preoperative visualization of the AKA. It can show proximity to the tumor and guide the local therapy, thereby avoiding critical intra- and postoperative situations.PMID:34331163 | DOI:10.1245/s10434-021-10381-8
Source: Ann Oncol - July 31, 2021 Category: Cancer & Oncology Authors: Andreas Schmidt Johann-Martin Hempel Verena Ellerkamp Steven W Warmann Ulrike Ernemann J örg Fuchs Source Type: research

Abstract 2107: YAP protein expression and subcellular localization in pediatric liver tumors
Conclusion: All HCC tumors and 33% of the HB showed an increase in the nuclear localization of transcription factor YAP. The increased activity of YAP in the nuclei of tumor cells may indicate a crucial role for YAP in tumor proliferation and survival. Targeting YAP or its upstream pathway (Hippo) may provide a novel target for therapy.Citation Format: Michael J. LaQuaglia, James Grijalva, Kaly Mueller, Antonio Perez-Atayde, Heung Bae Kim, Ghazaleh Sadri-Vakili, Khashayar Vakili. YAP protein expression and subcellular localization in pediatric liver tumors. [abstract]. In: Proceedings of the 106th Annual Meeting of the Ame...
Source: Cancer Research - August 2, 2015 Category: Cancer & Oncology Authors: LaQuaglia, M. J., Grijalva, J., Mueller, K., Perez-Atayde, A., Kim, H. B., Sadri-Vakili, G., Vakili, K. Tags: Molecular and Cellular Biology Source Type: research

Selective Toxicity of Persian Gulf Sea Cucumber (Holothuria parva) and Sponge (Haliclona oculata) Methanolic Extracts on Liver Mitochondria Isolated from an Animal Model of Hepatocellular Carcinoma
Conclusions: Our results suggest that H. parva and H. oculata may be promising therapeutic candidates for the treatment of HCC, following further confirmatory in vivo experiments and clinical trials.,Results: Our results showed that H. parva methanolic extracts (250, 500, and 1000 µg/mL) and H. oculata methanolic extracts (200, 400, and 800 µg/mL) increased reactive oxygen species (ROS) formation, mitochondrial membrane potential (MMP), mitochondrial swelling, and cytochrome c release in the mitochondria obtained from cancerous hepatocytes, but not in mitochondria obtained from non-cancerous liver hepatocytes. These extr...
Source: Hepatitis Monthly - December 21, 2015 Category: Infectious Diseases Source Type: research

Ovine Pulmonary Adenocarcinoma: A Unique Model to Improve Lung Cancer Research
Conclusion As outlined here, OPA has great potential to be used as an excellent model for studying multiple aspects of human lung cancer biology. As a result, in vivo and in vitro OPA experimental models have been developed for the study of JSRV Env mediated oncogenesis; these have been successfully used to determine the molecular pathways involved in lung cancer pathogenesis. However, the potential for OPA to be used as a pre-clinical animal model for assessing human lung cancer treatment strategies has yet to be fully exploited. Naturally occurring OPA cases are readily available from infected flocks due to the endemic ...
Source: Frontiers in Oncology - April 25, 2019 Category: Cancer & Oncology Source Type: research

EANM procedure guideline for the treatment of liver cancer and liver metastases with intra-arterial radioactive compounds
Eur J Nucl Med Mol Imaging. 2022 Feb 11. doi: 10.1007/s00259-021-05600-z. Online ahead of print.ABSTRACTPrimary liver tumours (i.e. hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICC)) are among the most frequent cancers worldwide. However, only 10-20% of patients are amenable to curative treatment, such as resection or transplant. Liver metastases are most frequently caused by colorectal cancer, which accounts for the second most cancer-related deaths in Europe. In both primary and secondary tumours, radioembolization has been shown to be a safe and effective treatment option. The vast potential of per...
Source: Molecular Medicine - February 11, 2022 Category: Molecular Biology Authors: M Weber M Lam C Chiesa M Konijnenberg M Cremonesi P Flamen S Gnesin L Bodei T Kracmerova M Luster E Garin K Herrmann Source Type: research