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Total 149 results found since Jan 2013.

Providing End-of-Life Care in the Community: What Are the Challenges in Malaysia?
J Hosp Palliat Care. 2022 Sep 1;25(3):133-137. doi: 10.14475/jhpc.2022.25.3.133.ABSTRACTA 72-year-old woman with metastatic lung cancer to bone and brain and with left external iliac vein thrombosis was under the care of a community palliative care provider. She experienced an acute pain crisis due to acute limb ischemia of the left lower limb. Goals-of-care discussions were held with the patient and her family; she prioritized symptom control and end-of-life care at home. The family and patient were aware of her short prognosis. Her complex pain was managed by the community palliative team, and her family was empowered to...
Source: Cancer Control - September 7, 2023 Category: Cancer & Oncology Authors: Yoke Yeng Leong Ednin Hamzah Sylvia McCarthy Zee Nee Lim Source Type: research

Are psychedelics the answer to chronic pain: a review of current literature
Pain Pract. 2023 Jan 4. doi: 10.1111/papr.13203. Online ahead of print.ABSTRACTChronic pain is a common and complex problem, with an unknown etiology. Psychedelics like lysergic acid diethylamide (LSD) and psilocybin, may play a role in the management of chronic pain. Through activation of the serotonin-2A (5-HT2A ) receptor, several neurophysiological responses result in the disruption of functional connections in brain regions associated with chronic pain. Healthy reconnections can be made through neuroplastic effects, resulting in sustained pain relief. However, this process is not fully understood and evidence of effic...
Source: Cancer Control - January 4, 2023 Category: Cancer & Oncology Authors: Nina I Kooijman Tim Willegers Anke Reuser Wim M Mulleners Cornelis Kramers Kris C P Vissers Selina E I van der Wal Source Type: research

Isolated trigeminal neuralgia: An early weird presentation of carcinoma breast
We report an interesting case of a 52-year-old postmenopausal female who presented with a 2-month history of headache, tingling sensation, and sharp shooting pain over the left face, followed by left facial paresthesia with pain over the maxillary region. Magnetic resonance imaging scan revealed presence of enplaque altered signal intensity soft-tissue lesion along the left 5th nerve from its origin at pons, and positron emission tomography with concurrent computed tomography showed a 2.9 cm × 2.6 cm intensely 18F-fluorodeoxyglucose-avid breast mass, in the upper outer quadrant of the right breast. Core-needle ...
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Irappa Madabhavi Malay Sarkar KS Sandeep Mitul Modi Source Type: research

Coping With the Side Effects of Kidney-Cancer Treatment
Not long ago, the treatment options available to people with metastatic kidney cancer were few and feeble. Surgical removal of the affected tissue was an effective and often durable fix for people with cancer that was confined to the kidneys. But for the roughly 30% to 40% of people with kidney cancer that spreads to other parts of the body, the prognosis was dispiritingly grim. Fortunately, things are much different today. “Since the early 2000s, we’ve had a class of drugs called blood-vessel inhibitors, and these made an immediate impact,” says Dr. Primo Lara, a professor, clinician, and director of the...
Source: TIME: Health - October 27, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized Cancer healthscienceclimate Source Type: news

Opioid withdrawal syndrome developing after long-term administration of naldemedine
Palliat Support Care. 2022 May 11:1-3. doi: 10.1017/S147895152200044X. Online ahead of print.ABSTRACTOBJECTIVE: One of the side effects of opioid administration is opioid-induced constipation (OIC). To address this side effect, the oral peripheral μ opioid receptor antagonist naldemedine was developed. As this drug does not cross the blood-brain barrier, it is thought that it does not lead to opioid withdrawal syndrome (OWS) with central nervous system symptoms.METHODS: Here, we report a cancer patient who presented with symptoms centered round anxiety and irritation 4 months after administration of naldemedine for OIC an...
Source: Palliative and Supportive Care - May 11, 2022 Category: Palliative Care Authors: Mayumi Ishida Nozomu Uchida Akira Yabuno Kosei Hasegawa Naoki Mizunuma Takao Takahashi Hideki Onishi Source Type: research

Supporting Patients Through Their Radiation Therapy: Lung Cancer, Brain Metastases, and Bone Metastases (FR207)
Outcomes1. Describe common evidence-based indications for radiation therapy for lung cancer patients, including brain and bone metastatic disease2. Identify common acute and late-onset adverse effects associated with radiation therapy and describe ways to mitigate them3. Recognize opportunities for integrating palliative medicine into the care of patients receiving radiation therapyApproximately 60% of patients with cancer receive radiation therapy during their illness, and nearly half of these patients are treated with palliative intent.
Source: Journal of Pain and Symptom Management - April 12, 2022 Category: Palliative Care Authors: Shayna Rich, Dana Guyer, Joshua Jones, Emily Martin Source Type: research

Opioid Equianalgesic Tables are Broken
by Drew Rosielle (@drosielle)I am proposing we do away with equianalgesic table (EAT) as a tool to inform clinical decisions about opioid rotations/conversions. Fundamentally, EATs create too many problems, and there are simpler and safer ways to teach clinicians how to convert between different opioids.Part 1: New Data Can ' t Fix the EATA couple HPM fellows every year ask me which table do I prefer to use —the old EAT or the new one? By the old one, they refer to the table most of us used or were at least deeply familiar with for the last 10-20 years. By the new one, they mean the one created by Dr. Mary Lynn McPherson...
Source: Pallimed: A Hospice and Palliative Medicine Blog - March 21, 2022 Category: Palliative Care Tags: opioid pain rosielle Source Type: blogs

Total Pain Management and a Malignant Wound: The Importance of Early Palliative Care Referral
We present the case of a 53-year-old male with a three-year history of stage IV breast cancer. He was admitted to the internal medicine ward in July 2021 with uncontrolled pain related to a malignant wound in the left hemithorax. This was a case with physical, emotional, social, and existential factors contributing to severe pain, necessitating a multidisciplinary approach for adequate relief. Opioid titration and insomnia and anxiety treatment were initiated. Dressing care was applied with metronidazole impregnation and aminocaproic acid for hemorrhagic spots, followed by fat gauze. He was proposed to undergo antalgic rad...
Source: Cancer Control - February 2, 2022 Category: Cancer & Oncology Authors: Catarina Faria Vanessa Branco Pedro Ferreira Cristina Gouveia Sara Trevas Source Type: research

What Considerations Are There in Prescribing a Medical Cannabis Card?
Discussion Cannabis is a plant which has many pharmacologically active compounds with THC or tetrahydrocannabinol and cannabidiol (CBD) being the most studied. For this case, medical cannabis will be used to describe different forms of the plant used to pharmacologically treat a variety of medical conditions. Medical cannabis has been proposed and mainly studied in adult populations. Qualifying conditions for use of medical cannabis in this author’s US state currently include: ” Cancer – if the illness or its treatment produces one or more of the following: severe or chronic pain, nausea or severe vomitin...
Source: PediatricEducation.org - January 31, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Tube feeding in patients with dementia is associated with a longer palliative care unit stay
CONCLUSION: The present study showed that, in patients with an established diagnosis of dementia, TF is common and independently associated with a longer length of PCU stay. Nevertheless, the study was underpowered and the results deserve confirmation in larger studies.PMID:34971282 | DOI:10.1002/alz.052919
Source: The Journal of Alzheimers Association - December 31, 2021 Category: Psychiatry Authors: Hilal Zengin Ilker Tasci Source Type: research