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Bone marrow mesenchymal stem cell exosomal miR-345-3p ameliorates cerebral ischemia-reperfusion injury by targeting TRAF6
CONCLUSION: This study found that BMSCs-exosomal miR-345-3p protected against CIR injury by decreasing TRAF6.PMID:37670712 | DOI:10.2174/1567202620666230905121102
Source: Current Neurovascular Research - September 6, 2023 Category: Neurology Authors: Dan Hou Lei Zhang Yujie Hu Guoshuai Yang Dan Yu Source Type: research
2022 Cannon Lecture: An ode to signal transduction - how the growth hormone pathway revealed insight into height, malignancy and obesity
Am J Physiol Endocrinol Metab. 2023 Sep 6. doi: 10.1152/ajpendo.00265.2023. Online ahead of print.ABSTRACTWalter Cannon was a highly regarded American neurologist and physiologist with extremely broad interests. In the tradition of Cannon and his broad interests, we discuss our laboratory's multi-faceted work in signal transduction over the past 40+ years. We show how our questioning of how growth hormone (GH) in the blood communicates with cells throughout the body to promote body growth and regulate body metabolism led to insight into not only body height, but also important regulators of malignancy and body weight. High...
Source: Am J Physiol Endocri... - September 6, 2023 Category: Endocrinology Authors: Christin Carter-Su Lawrence S Argetsinger Nadezhda V Svezhova Source Type: research
Bone marrow mesenchymal stem cell exosomal miR-345-3p ameliorates cerebral ischemia-reperfusion injury by targeting TRAF6
CONCLUSION: This study found that BMSCs-exosomal miR-345-3p protected against CIR injury by decreasing TRAF6.PMID:37670712 | DOI:10.2174/1567202620666230905121102
Source: Current Neurovascular Research - September 6, 2023 Category: Neurology Authors: Dan Hou Lei Zhang Yujie Hu Guoshuai Yang Dan Yu Source Type: research
2022 Cannon Lecture: An ode to signal transduction - how the growth hormone pathway revealed insight into height, malignancy and obesity
Am J Physiol Endocrinol Metab. 2023 Sep 6. doi: 10.1152/ajpendo.00265.2023. Online ahead of print.ABSTRACTWalter Cannon was a highly regarded American neurologist and physiologist with extremely broad interests. In the tradition of Cannon and his broad interests, we discuss our laboratory's multi-faceted work in signal transduction over the past 40+ years. We show how our questioning of how growth hormone (GH) in the blood communicates with cells throughout the body to promote body growth and regulate body metabolism led to insight into not only body height, but also important regulators of malignancy and body weight. High...
Source: American Journal of Physiology. Endocrinology and Metabolism - September 6, 2023 Category: Physiology Authors: Christin Carter-Su Lawrence S Argetsinger Nadezhda V Svezhova Source Type: research
Bone marrow mesenchymal stem cell exosomal miR-345-3p ameliorates cerebral ischemia-reperfusion injury by targeting TRAF6
CONCLUSION: This study found that BMSCs-exosomal miR-345-3p protected against CIR injury by decreasing TRAF6.PMID:37670712 | DOI:10.2174/1567202620666230905121102
Source: Current Neurovascular Research - September 6, 2023 Category: Neurology Authors: Dan Hou Lei Zhang Yujie Hu Guoshuai Yang Dan Yu Source Type: research
2022 Cannon Lecture: An ode to signal transduction - how the growth hormone pathway revealed insight into height, malignancy and obesity
Am J Physiol Endocrinol Metab. 2023 Sep 6. doi: 10.1152/ajpendo.00265.2023. Online ahead of print.ABSTRACTWalter Cannon was a highly regarded American neurologist and physiologist with extremely broad interests. In the tradition of Cannon and his broad interests, we discuss our laboratory's multi-faceted work in signal transduction over the past 40+ years. We show how our questioning of how growth hormone (GH) in the blood communicates with cells throughout the body to promote body growth and regulate body metabolism led to insight into not only body height, but also important regulators of malignancy and body weight. High...
Source: Am J Physiol Endocri... - September 6, 2023 Category: Endocrinology Authors: Christin Carter-Su Lawrence S Argetsinger Nadezhda V Svezhova Source Type: research
Bone marrow mesenchymal stem cell exosomal miR-345-3p ameliorates cerebral ischemia-reperfusion injury by targeting TRAF6
CONCLUSION: This study found that BMSCs-exosomal miR-345-3p protected against CIR injury by decreasing TRAF6.PMID:37670712 | DOI:10.2174/1567202620666230905121102
Source: Current Neurovascular Research - September 6, 2023 Category: Neurology Authors: Dan Hou Lei Zhang Yujie Hu Guoshuai Yang Dan Yu Source Type: research
Flavonoids as promising anticancer therapeutics: Contemporary research, nanoantioxidant potential, and future scope
Phytother Res. 2023 Sep 5. doi: 10.1002/ptr.7975. Online ahead of print.ABSTRACTFlavonoids are natural polyphenolic compounds considered safe, pleiotropic, and readily available molecules. It is widely distributed in various food products such as fruits and vegetables and beverages such as green tea, wine, and coca-based products. Many studies have reported the anticancer potential of flavonoids against different types of cancers, including solid tumors. The chemopreventive effect of flavonoids is attributed to various mechanisms, including modulation of autophagy, induction of cell cycle arrest, apoptosis, and antioxidant...
Source: Cell Research - September 5, 2023 Category: Cytology Authors: Mukta Gupta Javed Ahmad Javed Ahamad Snehashis Kundu Archit Goel Awanish Mishra Source Type: research
Transcranial Direct Current Stimulation in Nicotine Use: Nursing Implications for Patient Outcomes
J Addict Nurs. 2023 Jul-Sep 01;34(3):E74-E78. doi: 10.1097/JAN.0000000000000542.ABSTRACTTobacco use is a leading cause of cancer, cardiovascular and respiratory disease, and preventable death in the United States. The brains of individuals with nicotine dependence are characterized by damaged mesolimbic pathways in the medial portion of the limbic and frontal lobes, creating positive reinforcing mechanisms. Transcranial direct current stimulation (tDCS) targets this neuroadaptation to improve smokers' nicotine-related outcomes, such as craving and smoking behavior, by depolarizing or hyperpolarizing the neurons of the brai...
Source: Cancer Control - September 5, 2023 Category: Cancer & Oncology Authors: Seok Hyun Gwon Han-Joo Lee Hyochol Brian Ahn Source Type: research
Toward Precision Oncology in Glioblastoma with a Personalized Cancer Genome Reporting Tool and Genetic Changes Identified by Whole Exome Sequencing
This study demonstrates the prospects of precision/personalized medicine in GBM specifically, and neurosurgical oncology more generally, including the potential for genomic profiling coupled with personalized cancer genome reporting. Further research and larger studies are warranted to validate these findings and advance the treatment options and outcomes for patients with GBM.PMID:37669106 | DOI:10.1089/omi.2023.0117
Source: Cancer Control - September 5, 2023 Category: Cancer & Oncology Authors: Onur Erdogan Şeyma Çolakoğlu Özkaya Can Erzik Kaya Bilguvar Kaz ım Yalçın Arga Fatih Bayrakl ı Source Type: research
