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Cancer: Squamous Cell Carcinoma
Infectious Disease: Fusobacterium
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Total 43 results found since Jan 2013.
Intracellular Fusobacterium nucleatum infection increases METTL3-mediated m6A methylation to promote the metastasis of esophageal squamous cell carcinoma
CONCLUSIONS: This study indicates that intracellular Fn infection promotes ESCC development and metastasis, and eradicating Fn infection may be a promising strategy for treating ESCC.PMID:37619934 | DOI:10.1016/j.jare.2023.08.014
Source: Cell Research - August 24, 2023 Category: Cytology Authors: Songhe Guo Fangfang Chen Linfang Li Dou Shuheng Qifan Li Yuying Huang Zijun Li Wanli Liu Ge Zhang Source Type: research
Cathepsin-K inhibition enhances anti-cancerous activity within oral squamous cell carcinoma cells: Uncloaking the potency of new K21 formulation
CONCLUSION: Over expression of CatK can be reduced by a newly developed targeted K21 based drug delivery system leading to reduced migration and adhesion of oral squamous cell carcinoma cells. The K21 drug formulation can have great potential for cancer therapies due to targeting and cytotoxicity effects.PMID:37356748 | DOI:10.1016/j.yexcr.2023.113687
Source: Experimental Cell Research - June 25, 2023 Category: Cytology Authors: Rehan Imad Zeeshan Sheikh Mallikarjuna Rao Pichika Mak Kit-Kay Rehan Ahmed Siddiqui Syed Nudrat Nawaid Shah Spoorthi Banavar Jukka Matinlinna Seow Liang Lin Umer Daood Source Type: research
Subtype-based microbial analysis in non-small cell lung cancer
CONCLUSIONS: Microbiome diversity is crucial for maintaining homeostasis in the lung environment, and dysbiosis may be related to the development and prognosis of lung cancer. The mortality rate was high, and the microbiome was not diverse in SqCC. Further large-scale studies are required to investigate the role of the microbiome in the development of different lung cancer types.PMID:37345463 | DOI:10.4046/trd.2022.0149
Source: Respiratory Care - June 22, 2023 Category: Respiratory Medicine Authors: Hye Jin Jang Eunkyung Lee Young-Jae Cho Sang Hoon Lee Source Type: research
Cancers, Vol. 15, Pages 2668: Evaluation of the Oesophagogastric Cancer-Associated Microbiome: A Systematic Review and Quality Assessment
Conclusions. Functional analysis of cancer pathways can infer tumorigenesis within the cancer–microbe–immune axis. There is evidence that study design, experimental protocols and analytical techniques could be improved to achieve more accurate and representative results. Whole-genome sequencing is recommended to identify key metabolic and functional capabilities of candidate bacteria biomarkers.
Source: Cancers - May 9, 2023 Category: Cancer & Oncology Authors: Bhamini Vadhwana Munir Tarazi Piers R. Boshier George B. Hanna Tags: Review Source Type: research
Variations in protein expression associated with oral cancer
CONCLUSION: The present study revealed considerable changes in the expression of bacterial proteins in OSCC and enrich our understanding in this point.PMID:37038789 | DOI:10.3233/THC-236014
Source: Technology and Health Care - April 11, 2023 Category: Medical Devices Authors: Wei Jiang Zhiyan He Youmeng Zhang Shujun Ran Zhe Sun Weixu Chen Source Type: research
Oral Microflora and Its Potential Carcinogenic Effect on Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis
Cureus. 2023 Jan 9;15(1):e33560. doi: 10.7759/cureus.33560. eCollection 2023 Jan.ABSTRACTThe oral cavity has the second largest and most diverse microflora. A wide variety of bacteria, viruses, and fungi are present in the oral cavity. A significant number of studies have shown the important role of oral microflora in the initiation and pathogenesis of oral squamous cell carcinoma (OSCC). Microorganisms like Staphylococcus, Streptococcus, Neisseria, Prevotella, Fusobacterium, Porphyromonas, Herpes Simplex Virus I (HSV-1), Epstein-Barr Virus (EBV), Human Papilloma Virus (HPV), Candida plays an important role in OSCC. Increa...
Source: Herpes - February 13, 2023 Category: Infectious Diseases Authors: Mudiyayirakkani Muthusamy Pratibha Ramani Reshma Poothakulath Krishnan Hemashree K Gheena Sukumaran Abilasha Ramasubramanian Source Type: research
Oral bacterial contributions to gingival carcinogenesis and progression
Cancer Prev Res (Phila). 2023 Jan 23:CAPR-22-0511. doi: 10.1158/1940-6207.CAPR-22-0511. Online ahead of print.ABSTRACTSeveral periodontitis-associated species induce genes related to cell proliferation, cell-cycle progression, apoptosis, intracellular transport, immune and inflammatory responses, carcinogenesis, and cancer progression. Here, we reviewed studies showing strong associations between gingival squamous cell carcinoma (GSCC) and three periodontitis-related oral bacteria (Porphyromonas gingivalis, Fusobacterium nucleatum, and Prevotella intermedia) in the microenvironment. These bacteria produce cytoplasmic lipop...
Source: Cell Research - January 23, 2023 Category: Cytology Authors: Kohei Okuyama Souichi Yanamoto Source Type: research
