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Cancer: Squamous Cell Carcinoma
Infectious Disease: Human Papillomavirus (HPV)
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Total 1532 results found since Jan 2013.
Neuroendocrine carcinoma of the cervix: About a rare case and literature review
CONCLUSION: To improve the survival of patients with large-cell neuroendocrine carcinomas of the uterine cervix, it is imperative to conduct multicenter clinical trials aimed at defining an effective, standardized treatment.PMID:37729821 | DOI:10.1016/j.ijscr.2023.108835
Source: Hand Surgery - September 20, 2023 Category: Surgery Authors: Imane El Abbassi S O Tanguara Y Bencherifi M Ennachit M Benhessou M El Kerroumi Source Type: research
Targeted proteomic quantitation of NRF2 signaling and predictive biomarkers in HNSCC
Mol Cell Proteomics. 2023 Sep 14:100647. doi: 10.1016/j.mcpro.2023.100647. Online ahead of print.ABSTRACTThe NFE2L2(NRF2) oncogene and transcription factor drives a gene expression program that promotes cancer progression, metabolic reprogramming, immune evasion and chemoradiation resistance. Patient stratification by NRF2 activity may guide treatment decisions to improve outcome. Here, we developed a mass spectrometry (MS)-based targeted proteomics assay based on internal standard triggered parallel reaction monitoring (IS-PRM) to quantify 69 NRF2 pathway components and targets, as well as 21 proteins of broad clinical si...
Source: Molecular and Cellular Proteomics : MCP - September 16, 2023 Category: Molecular Biology Authors: Nathan T Wamsley Emily M Wilkerson Li Guan Kyle M LaPak Travis P Schrank Brittany J Holmes Robert W Sprung Petra Erdmann Gilmore Sophie P Gerndt Ryan S Jackson Randal C Paniello Patrik Pipkorn Sidharth V Puram Jason T Rich Reid R Townsend Jos é P Zevallo Source Type: research
Prevalence of human papillomavirus infection in abnormal pap smears
CONCLUSION: Our study shows that the percentage of HR-HPV-positive case increases with the severity of cytologic morphology. HPV had 4 times higher positivity in squamous intraepithelial lesion as compared to ASCUS.PMID:37681080 | PMC:PMC10481853 | DOI:10.25259/Cytojournal_8_2021
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Jaya Mishra Sweety Kalantri Vandana Raphael Biswajit Dey Yookarin Khonglah Ananya Das Source Type: research
Cancers, Vol. 15, Pages 4405: Squamous Cell Carcinoma of the Oral Cavity, Oropharynx, and Larynx: A Scoping Review of Treatment Guidelines Worldwide
Maria Paula Curado
Head and neck cancer (HNC) treatments have been based on single or multimodal therapies with surgery, radiotherapy (RT), chemotherapy, and immunotherapy. However, treatment recommendations among countries may differ due to technological/human resources and usual local practices. This scoping review aims to identify, compare, and map the clinical practice guidelines (CPGs) for treating squamous cell carcinoma (SCC) of the oral cavity, oropharynx, and larynx worldwide. A search strategy on global CPGs for HNC was performed by using five electronic databases and grey literature. CPGs were selected for ...
Source: Cancers - September 3, 2023 Category: Cancer & Oncology Authors: Lady Paola Aristizabal Arboleda Genival Barbosa de Carvalho Alan Roger Santos-Silva Gisele Aparecida Fernandes Jose Guilherme Vartanian David I. Conway Shama Virani Paul Brennan Luiz Paulo Kowalski Maria Paula Curado Tags: Systematic Review Source Type: research
Whole-genome CpG-resolution DNA Methylation Profiling of HNSCC Reveals Distinct Mechanisms of Carcinogenesis for Fine-scale HPV+ Cancer Subtypes
This study revealed that the previously observed hypermethylation of HPV(+) HNSCC is due solely to the IMU subtype, illustrating the importance of fine-scale subtype analysis in such a heterogeneous disease. Particularly, IMU has significantly higher methylation of transposable elements, which can be tested as a prognosis biomarker in future translational studies.PMID:37654626 | PMC:PMC10467604 | DOI:10.1158/2767-9764.CRC-23-0009
Source: Cell Research - September 1, 2023 Category: Cytology Authors: Tingting Qin Shiting Li Leanne E Henry Elysia Chou Raymond G Cavalcante Bailey F Garb Nisha J D'Silva Laura S Rozek Maureen A Sartor Source Type: research
Evaluation of programmed cell death ligand 1 expression in a contemporary cohort of penile squamous cell carcinoma and its correlation with clinicopathologic and survival parameters: A study of 134 patients
CONCLUSIONS: Overall, PD-L1 expression is associated with high-grade and metastatic tumors. Lower PD-L1 expression is observed more frequently in HPV-associated (warty or basaloid) subtypes than in other, predominantly HPV-independent types. As a result, PD-L1 positivity, including higher expression, portends lower overall and cancer-specific survival. These data provide a rational for further investigating PD-L1-based immunotherapeutics in PC.PMID:37639681 | DOI:10.1093/ajcp/aqad107
Source: American Journal of Clinical Pathology - August 28, 2023 Category: Pathology Authors: Anandi Lobo Sourav K Mishra Shilpy Jha Ankit Tiwari Rahul Kapoor Shivani Sharma Seema Kaushal N Sri Kiranmai M Rakshitha Das Kamal P Peddinti Shailendra K Sharma Nitin Bhardwaj Samriti Arora Deepika Jain Ekta Jain Gauri Munjal Sayali Shinde Vipra Malik He Source Type: research
Vulvar squamous cell carcinoma due to human papillomavirus type 11
Skin Res Technol. 2023 Aug;29(8):e13436. doi: 10.1111/srt.13436.NO ABSTRACTPMID:37632178 | DOI:10.1111/srt.13436
Source: Cell Research - August 26, 2023 Category: Cytology Authors: Pati Aji Achdiat Retno Hesty Maharani Nizami Hamada Reiva Farah Dwiyana Laila Tsaqilah Hermin Aminah Usman None Zulfan Source Type: research
