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Cancer: Squamous Cell Carcinoma
Drug: Docetaxel
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Total 152 results found since Jan 2013.
Neoadjuvant triplet chemotherapy with docetaxel, cisplatin plus 5-FU vs docetaxel, cisplatin plus S-1 for advanced esophageal squamous cell carcinoma: Propensity score matched analysis
CONCLUSIONS: Neoadjuvant DCS therapy for resectable advanced ESCC did not result in significantly higher clinical and pathological response than neoadjuvant DCF therapy. However, neoadjuvant DCS therapy for resectable ESCC required comparatively shorter hospital stays and incurred lower costs, making it an attractive therapeutic option.PMID:37708864 | DOI:10.1159/000533790
Source: Oncology - September 14, 2023 Category: Cancer & Oncology Authors: Junya Kitadani Toshiyasu Ojima Keiji Hayata Taro Goda Akihiro Takeuchi Shinta Tominaga Naoki Fukuda Tomoki Nakai Hiroki Yamaue Manabu Kawai Source Type: research
Identification of an endoplasmic reticulum stress-related prognostic risk model with excellent prognostic and clinical value in oral squamous cell carcinoma
CONCLUSION: A prognostic model with high clinical application value was constructed. Immune cells, cellular stemness, and TMB may be involved in the progression of OSCC.PMID:37647077 | DOI:10.18632/aging.204983
Source: Aging - August 30, 2023 Category: Biomedical Science Authors: Mingyang Cheng Xin Fan Mu He Xianglin Dai Xiaoli Liu Jinming Hong Laiyu Zhang Lan Liao Source Type: research
Survival Impact of Second-Line Immune Checkpoint Inhibitors in Older Patients With Advanced Squamous-Cell NSCLC: Post Hoc Analysis of the CAPITAL Study
CONCLUSIONS: We found that second-line ICI treatment seemed to have a little impact on OS.PMID:37304652 | PMC:PMC10250914 | DOI:10.1016/j.jtocrr.2023.100514
Source: Clinical Lung Cancer - June 12, 2023 Category: Cancer & Oncology Authors: Yoshihito Kogure Akiko Kada Hiroya Hashimoto Shinji Atagi Yuichi Takiguchi Hideo Saka Noriyuki Ebi Akira Inoue Takayasu Kurata Yuka Fujita Yoichi Nishii Hidetoshi Itani Takeo Endo Akiko M Saito Takuo Shibayama Nobuyuki Yamamoto Akihiko Gemma Source Type: research
Nanoencapsulation of Docetaxel Induces Concurrent Apoptosis and Necroptosis in Human Oral Cancer Cells (SCC-9) via TNF- α/RIP1/RIP3 Pathway
Indian J Clin Biochem. 2023 Jul;38(3):351-360. doi: 10.1007/s12291-022-01055-7. Epub 2022 Aug 9.ABSTRACTHuman oral squamous cell carcinoma is the sixth most frequent malignant cancer, with an unacceptably high death rate that affects people's health. Albeit, there are several clinical approaches for diagnosing and treating oral cancer they are still far from ideal. We previously synthesised and characterised the docetaxel nanoformulation (PLGA-Dtx) and discovered that docetaxel nanoencapsulation may suppress oral cancer cells. The goal of this study was to figure out the mechanism involved in the suppression of oral cancer...
Source: Clinical Biochemistry - May 26, 2023 Category: Biochemistry Authors: Parul Gupta Arpita Singh Ajay Kumar Verma Surya Kant Anuj Kumar Pandey Anupam Mishra Puneet Khare Ved Prakash Source Type: research
Paclitaxel combined with platinum (PTX) versus fluorouracil combined with cisplatin (PF) in the treatment of unresectable esophageal cancer: a systematic review and meta-analysis of the efficacy and toxicity of two different regimens
CONCLUSIONS: PTX may be the preferred regimen for CCRT of esophageal squamous cell carcinoma, with better short-term therapeutic effect and 2-year OS rate and lower gastrointestinal toxicity.PMID:37201087 | PMC:PMC10186517 | DOI:10.21037/jgo-23-33
Source: Cancer Control - May 18, 2023 Category: Cancer & Oncology Authors: Li'ang Xu Xiaoxi Chen Lan Wang Jing Han Qi Wang Shutang Liu Xiaolin Zhang Chun Han Source Type: research
Therapeutic strategy aiming at R0 resection for borderline-resectable esophageal squamous cell carcinoma using induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil
CONCLUSION: DCF induction therapy and subsequent CS or definitive CRT are promising treatment strategies for cT3br esophageal SCC.PMID:37060435 | DOI:10.1007/s11748-023-01934-7
Source: Cancer Control - April 15, 2023 Category: Cancer & Oncology Authors: Masanobu Nakajima Hiroto Muroi Maiko Kikuchi Tsukasa Kubo Noboru Inoue Keisuke Ihara Masatoshi Nakagawa Shinji Morita Takatoshi Nakamura Kazuyuki Kojima Source Type: research
M1 macrophage predicted efficacy of neoadjuvant camrelizumab combined with chemotherapy vs chemotherapy alone for locally advanced ESCC: A pilot study
CONCLUSIONS: Neoadjuvant camrelizumab combined with chemotherapy improved ORR in locally advanced ESCC. M1-type tumor-associated macrophages and CD56dim NK cells might be utilized to predict camrelizumab efficacy.PMID:36969032 | PMC:PMC10038194 | DOI:10.3389/fonc.2023.1139990
Source: Cancer Control - March 27, 2023 Category: Cancer & Oncology Authors: Shu Wang Guanghui Xu Mengbin Li Jiyang Zheng Yuhao Wang Xiangying Feng Jialin Luo Shibo Wang Huan Liu Weiming Duan Hushan Zhang Depei Huang Feilong Zhao Yongzhan Nie Jianjun Yang Source Type: research
Clinical significance and integrative analysis of the cuproptosis-associated genes in head and neck squamous cell carcinoma
Aging (Albany NY). 2023 Mar 20;15. doi: 10.18632/aging.204579. Online ahead of print.ABSTRACTHead and neck squamous cell carcinoma (HNSC) is a kind of malignant tumor originating from the oropharynx, larynx, nasopharynx and oral cavity. The incidence of HNSC is increasing and it is the sixth malignant tumor in the world at present. "Cuprotosis" is a novel cuper-dependent cell death mode that is closely related to mitochondrial respiration. Tumorigenesis is closely related to the dysregulation of cell death. However, the relationship between cuprotosis and HNSC remains unclear. Here, we investigated the association between ...
Source: Aging - March 22, 2023 Category: Biomedical Science Authors: Qiu Peng Xianjie Jiang Shiming Tan Xuemeng Xu Longzheng Xia Nayiyuan Wu Jinguan Lin Linda Oyang Yanyan Tang Mingjing Peng Min Su Xia Luo Yaqian Han Qianjin Liao Yujuan Zhou Source Type: research
