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Melanoma: How and When to Consider Clinical Diagnostic Technologies
In response to rising rates of melanoma worldwide, novel non-invasive melanoma detection techniques are emerging to facilitate the early detection of melanoma and decrease unnecessary biopsies of benign pigmented lesions. Because they often report similar study findings, it may be difficult to determine how best to incorporate these technologies into clinical practice based on their supporting studies alone. As an expansion of the recent article by Fried et al.1, which reviewed the clinical data supporting these non-invasive melanoma detection techniques, the first article in this continuing medical education series provid...
Source: Journal of the American Academy of Dermatology - December 13, 2021 Category: Dermatology Authors: Lauren Skudalski, Reid Waldman, Philip E. Kerr, Jane M. Grant-Kels Source Type: research
Racial/Ethnic Health Disparities in Dermatology in the United States Part 2: Disease-specific Epidemiology, Characteristics, Management, and Outcomes
Racial and ethnic disparities in dermatology negatively affect outcomes such as mortality and quality of life. Dermatologists and dermatologic surgeons should be familiar with disease-specific inequities that may influence their practice. The second article in this two-part continuing medical education series highlights gaps in frequency, clinical presentation, management, and outcomes by race and ethnicity. We review cutaneous malignancies including basal cell carcinoma, squamous cell carcinoma, melanoma, Merkel cell carcinoma, dermatofibrosarcoma protuberans, and cutaneous T cell lymphoma, and inflammatory disorders incl...
Source: Journal of the American Academy of Dermatology - February 6, 2022 Category: Dermatology Authors: Kimberly Shao, Jette Hooper, Hao Feng Source Type: research
Skin cancer: Primary, secondary, and tertiary prevention. Part II.
Skin cancer is the most commonly diagnosed cancer worldwide. Understanding the natural history of skin cancer will provide a framework for the creation of prevention and control strategies that aim to reduce skin cancer burden. The strategies include health promotion, primary prevention, secondary prevention, and tertiary prevention. Health promotion and primary prevention were covered in the first part of this 2-part review. The second part covers the secondary and tertiary prevention of skin cancer.
Source: Journal of the American Academy of Dermatology - February 14, 2022 Category: Dermatology Authors: Kristina D. Rojas, Mariana E. Perez, Michael A. Marchetti, Anna J. Nichols, Frank J. Penedo, Natalia Jaimes Tags: Continuing medical education Source Type: research
Skin cancer: Primary, secondary, and tertiary prevention. Part I
Skin cancer is the most commonly diagnosed cancer worldwide. Understanding the natural history of skin cancer provides the framework for the creation of prevention and control strategies that aim to reduce the skin cancer burden. Based on the target (individual vs population), disease stage, and risk factors (modifiable vs nonmodifiable), strategies can be categorized into 4 levels —health promotion (also known as primordial prevention), primary prevention, secondary prevention, and tertiary prevention.
Source: Journal of the American Academy of Dermatology - February 14, 2022 Category: Dermatology Authors: Mariana Perez, Juanita Arango Abisaad, Kristina D. Rojas, Michael A. Marchetti, Natalia Jaimes Tags: Continuing medical education Source Type: research
CME examination Skin cancer quiz part 2: Question
Source: Journal of the American Academy of Dermatology - July 16, 2022 Category: Dermatology Tags: Continuing medical education Source Type: research
CME examination Skin cancer quiz part 1: Question
Source: Journal of the American Academy of Dermatology - July 16, 2022 Category: Dermatology Tags: Continuing medical education Source Type: research
Variations in genetics, biology, and phenotype of cutaneous disorders in skin of color – Part I: Genetic, biologic, and structural differences in skin of color
Skin of color (SOC) populations include those who identify as Black/African, Hispanic/Latinx, Asian/Pacific Islander, American Indian/Native Alaskan, Indigenous Australian, Middle Eastern, biracial/multiracial, or non-White; this list is far from exhaustive and may vary between and within cultures. Recent genetic and immunological studies have suggested that cutaneous inflammatory disorders (atopic dermatitis, psoriasis, and hidradenitis suppurativa) and malignancies (melanoma, basal cell carcinoma, and cutaneous T-cell lymphoma) may have variations in their immunophenotype among SOC.
Source: Journal of the American Academy of Dermatology - July 6, 2022 Category: Dermatology Authors: Jessica B. Brown-Korsah, Shanice McKenzie, Deega Omar, Nicole C. Syder, Nada Elbuluk, Susan C. Taylor Tags: Continuing medical education Source Type: research
Risk of melanoma and nonmelanoma skin cancer with immunosuppressants, part I: Calcineurin inhibitors, thiopurines, IMDH inhibitors, mTOR inhibitors, and corticosteroids
Immunosuppression is a well-documented risk factor for skin cancer, as exemplified by the 65- to 250-fold higher squamous cell carcinoma risk, 10-fold higher basal cell carcinoma risk, and 0 to 8-fold higher melanoma risk in solid organ transplant recipients (SOTRs) receiving potent, prolonged courses of immunosuppressive therapies. Numerous immune system components have been shown to either suppress or promote tumor growth, and immunosuppressive drugs may have additional effects on proliferative pathways independent of the immune system.
Source: Journal of the American Academy of Dermatology - November 29, 2022 Category: Dermatology Authors: Margaret Ann Kreher, Mary Margaret B. Noland, Sailesh Konda, Maria I. Longo, Rodrigo Valdes-Rodriguez Tags: Continuing medical education Source Type: research
Risk of melanoma and nonmelanoma skin cancer with immunosuppressants, part II: Methotrexate, alkylating agents, biologics, and small molecule inhibitors
In solid organ transplant recipients, skin cancer risk associated with posttransplant immunosuppression has been well-described, and screening practices generally reflect these risks. In addition to agents used posttransplant, other classes of immunosuppressants also have the potential to raise the risk of nonmelanoma skin cancer (NMSC) or melanoma. In the present manuscript, the evidence for melanoma and NMSC risk associated with methotrexate, cyclophosphamide, biologic cytokine inhibitors including TNF (tumor necrosis factor)-alpha and interleukin inhibitors, costimulation blockers such as abatacept, integrin inhibitors ...
Source: Journal of the American Academy of Dermatology - November 29, 2022 Category: Dermatology Authors: Margaret Ann Kreher, Sailesh Konda, Mary Margaret B. Noland, Maria I. Longo, Rodrigo Valdes-Rodriguez Tags: Continuing medical education Source Type: research
Q&A: Dr. John Mazziotta on the future of UCLA’s medical school and health system
Earlier in his life, Dr. John C. Mazziotta thought about becoming an architect. With a keen eye for form and function, he would apply his skills to the construction of great buildings. Instead, he chose medicine. Now, after more than 30 years at UCLA — where he has been chair of the department of neurology, an associate vice chancellor and executive vice dean, and founding director of the Ahmanson-Lovelace Brain Mapping Center — that style of visual thinking will serve him well in his new roles as vice chancellor for UCLA Health Sciences, dean of the David Geffen School of Medicine at UCLA and CEO of UCLA Health. “Th...
Source: UCLA Newsroom: Health Sciences - May 27, 2015 Category: Universities & Medical Training Source Type: news
What Do Germans Want to Know About Skin Cancer? A Nationwide Google Search Analysis From 2013 to 2017
Conclusions: Our study provides insight into terms and fields of interest related to skin cancer relevant to the German population. Furthermore, temporal trends and courses are shown. This information could aid in the development and implementation of effective and sustainable awareness campaigns by developing information sources targeted to the population’s broad interest or by implementing new Internet campaigns.
Source: Journal of Medical Internet Research - May 2, 2018 Category: General Medicine Authors: Stefanie Seidl Barbara Schuster Melvin R üth Tilo Biedermann Alexander Zink Source Type: research
Core Content for Undergraduate Medical Education in Spain: Recommendations of the Instructors’ Group of the Spanish Academy of Dermatology and Venereology (AEDV)
Conclusions The AEDV's group of instructors have defined their recommendations on the core content that medical faculties should adopt for the undergraduate subject of dermatology in Spain.
Source: Actas Dermo-Sifiliograficas - February 3, 2016 Category: Dermatology Source Type: research
Building a gold standard to construct search filters: a case study with biomarkers for oral cancer.
CONCLUSIONS: The gold standard dataset is likely to be high quality and useful for future development and evaluation of filters for OSCC studies of potential prognostic biomarkers.
IMPLICATIONS: The methodology we used is generalizable to other domains requiring a reference standard to evaluate the performance of search filters. A gold standard is essential because the labels regarding relevance enable computation of diagnostic metrics, such as sensitivity and specificity. Librarians and informationists with data analysis skills could contribute to developing gold standard datasets and subsequent filters tuned for thei...
Source: Journal of the Medical Library Association : JMLA - January 4, 2015 Category: Databases & Libraries Tags: J Med Libr Assoc Source Type: research
Melanoma Skin Self-Examination Education During Mammography: Health Burden of Women Impairs Implementation
AbstractIdentification of barriers to seeking health care for a concerning mole found during skin self-examination (SSE) by women educated during screening mammography. In this sequential mixed methods research, interviews with women who found a concerning mole and did not have health-care follow-up were analyzed and a survey was created. One year after SSE education, barriers to having health care for a self-identified concerning mole were assessed. The electronic medical records for all participants, who received education, were reviewed to ascertain who received health care related to a concerning mole or a screening ma...
Source: Journal of Cancer Education - February 23, 2020 Category: Cancer & Oncology Source Type: research
Abstracts from the First Annual Scholarly Day.
This article reprints a selection of the abstracts.
PMID: 26130877 [PubMed]
Source: Baylor University Medical Center Proceedings - July 1, 2015 Category: Universities & Medical Training Tags: Proc (Bayl Univ Med Cent) Source Type: research
