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Lifestyle and personal factors associated with having macroscopic residual disease after ovarian cancer primary cytoreductive surgery
CONCLUSIONS: The association between ET and having no macroscopic residual disease is plausible given a strong underlying biologic hypothesis between this exposure and diagnosis with HGSC. If this or the parity finding is replicated, these factors could be included in risk stratification models to determine whether HGSC patients should receive PCS or neoadjuvant chemotherapy.PMID:36401943 | DOI:10.1016/j.ygyno.2022.10.018
Source: Ann Oncol - November 19, 2022 Category: Cancer & Oncology Authors: Minh Tung Phung Penelope M Webb Anna DeFazio Sian Fereday Alice W Lee David D L Bowtell Peter A Fasching Ellen L Goode Marc T Goodman Beth Y Karlan Jenny Lester Keitaro Matsuo Francesmary Modugno James D Brenton Toon Van Gorp Paul D P Pharoah Joellen M Sc Source Type: research

Awareness of the non-contraceptive benefits of reversible contraceptive methods in a cohort of Brazilian women: an exploratory study
CONCLUSIONS: We found low awareness regarding the associated lower risk of ovarian, endometrial and cervical cancer associated with the use of some contraceptives, evidencing the need to provide more information about the non-contraceptive benefits during training for health care providers.PMID:35377262 | DOI:10.1080/13625187.2022.2054983
Source: The European Journal of Contraception and Reproductive Health Care - April 4, 2022 Category: Reproduction Medicine Authors: Luis Bahamondes None Mar ía Y Makuch Source Type: research

Unique transcriptomic changes underlie hormonal interactions during mammary histomorphogenesis in female pigs
Endocrinology. 2021 Dec 16:bqab256. doi: 10.1210/endocr/bqab256. Online ahead of print.ABSTRACTSuccessful lactation and the risk for developing breast cancer depend on growth and differentiation of the mammary gland (MG) epithelium that is regulated by ovarian steroids (17beta-estradiol [E] and progesterone [P]) and pituitary-derived prolactin (PRL). Given that the MG of pigs share histomorphogenic features present in the normal human breast, we sought to define the transcriptional responses within the MG of pigs following exposure to all combinations of these hormones. Hormone-ablated female pigs were administered combina...
Source: Endocrinology - December 17, 2021 Category: Endocrinology Authors: Josephine F Trott Anke Schennink Katherine C Horigan Danielle G Lemay Julia R Cohen Thomas R Famula Julie A Dragon Russell C Hovey Source Type: research

Method of contraception and risk of ovarian cancer data
Data Brief. 2021 Oct 10;39:107469. doi: 10.1016/j.dib.2021.107469. eCollection 2021 Dec.ABSTRACTThe data presented here were obtained for a New Zealand nationwide population-based case-control analysis undertaken to assess the association between ovarian cancer and depot medroxyprogesterone acetate (DMPA), intrauterine contraceptive devices (IUDs), and vasectomy of a woman's sexual partner (Chesang et al., 2021). The research involved women aged 35 to 69 years. Controls were randomly selected from the New Zealand electoral roll. Cases were women with a diagnosis of incident ovarian cancer recruited from the New Zealand Can...
Source: Cancer Control - December 13, 2021 Category: Cancer & Oncology Authors: Jacqueline Chesang Ann Richardson John Potter Mary Sneyd Pat Coope Source Type: research

Method of Contraception and Risk of Ovarian Cancer Data
Ann Epidemiol. 2021 Apr 22:S1047-2797(21)00062-4. doi: 10.1016/j.annepidem.2021.04.006. Online ahead of print.ABSTRACTThe data presented here were obtained for New Zealand nationwide population-based case-control analysis undertaken to assess the association between ovarian cancer and depot medroxyprogesterone acetate (DMPA), intrauterine contraceptive devices (IUDs), and vasectomy of a woman's sexual partner [1]. Approval to conduct the research was obtained from Southern Health and Disability Ethics Committee (13/STH/26) and the University of Canterbury Ethics Committee (HEC 2013/08). Recruitment of participants and data...
Source: Annals of Epidemiology - April 25, 2021 Category: Epidemiology Authors: Jacqueline Chesang Ann Richardson John Potter Mary Sneyd Pat Coope Source Type: research

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