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Predictors of Placement of Inpatient Palliative Care Consult Orders Among Patients With Breast, Lung, and Colon Cancer in a Safety Net Hospital System.
CONCLUSION: In this cohort of patients in a safety net hospital, markers of pain, advanced disease, and poor prognosis were associated with placement of inpatient palliative care consult orders. PMID: 29034687 [PubMed - as supplied by publisher]
Source: The American Journal of Hospice and Palliative Care - January 1, 2017 Category: Palliative Care Authors: Smith LN, Rhodes RL, Xuan L, Halm EA Tags: Am J Hosp Palliat Care Source Type: research

Colorectal cancer patients' preferences for type of caregiver during survivorship care.
CONCLUSIONS: CRC survivors frequently consult their GP in the current situation, and for symptoms that could alarm them to a possible recurrent disease consult both their GP and secondary care provider. Patient and tumour characteristics influence patients' preferred caregiver. PMID: 29343143 [PubMed - as supplied by publisher]
Source: Primary Care - January 17, 2018 Category: Primary Care Authors: Wieldraaijer T, Duineveld LAM, Donkervoort SC, Busschers WB, van Weert HCPM, Wind J Tags: Scand J Prim Health Care Source Type: research

Understanding Underuse of Advance Care Planning Among a Cohort of African American Patients With Advanced Cancer: Formative Research That Examines Gaps in Intent to Discuss Options for Care.
CONCLUSIONS: Despite being hospitalized with advanced cancer and having poor prognosis, intent to discuss ACP options, PC, and hospice in this population was variable, and completion of these activities was low. This formative research is needed to develop education and counseling interventions for this high-risk, vulnerable population. PMID: 31006248 [PubMed - as supplied by publisher]
Source: The American Journal of Hospice and Palliative Care - April 20, 2019 Category: Palliative Care Authors: Rhodes RL, Ukoha NCE, Williams KA, Elwood B, Knox-Rice T, Lee SC, Tiro JA, Skinner CS, Halm EA Tags: Am J Hosp Palliat Care Source Type: research

Collaborative care plans reduce subspecialty consults: the experience from a safety net hospital.
Abstract Several strategies have been proposed to improve referrals and communication between primary care providers (PCPs) and specialists. In this article, we describe the effectiveness of collaborative care plans (CCPs) in reducing utilization of specialist resources in a capitated health plan based in a safety net hospital. To operationalize individual care plans, a single clinic called the Total Care Clinic (TCC) was launched. Midlevel providers were assigned to subspecialties and trained in specific algorithms of care that they were responsible for. Midlevel providers in the TCC were invited to attend in-hou...
Source: The American Journal of Managed Care - March 31, 2020 Category: Health Management Authors: Mooradian AD, Stone R, Palacio C, Stewart E Tags: Am J Manag Care Source Type: research

Comparison of Cancer Care and Outcomes between a Public Safety-Net Hospital and a Private Cancer Center.
Abstract We compared the cancer outcomes and care-associated service defects between Jackson Memorial Hospital (ABC), a large public safety-net hospital, and Sylvester Comprehensive Cancer Center (XYZ), a private not-for-profit cancer center in patients with stage II-III colorectal cancer (CC) who received adjuvant chemotherapy (AC) and in patients with diffuse large B cell lymphoma (DLBCL). Colorectal cancer patients treated at ABC were more likely to have undergone urgent surgery. While in the CC cohort, three-year overall survival and relapse-free survival rates were significantly higher among patients treated ...
Source: Journal of Health Care for the Poor and Underserved - August 30, 2013 Category: Global & Universal Authors: Bayraktar UD, Warsch S, Chen E, Lima CM, Pereira D Tags: J Health Care Poor Underserved Source Type: research

Embedding electronic decision-support tools for suspected cancer in primary care: a qualitative study of GPs' experiences.
Abstract Aim The purpose of this evaluation was to obtain views from general practitioners (GPs) who piloted the electronic risk assessment tools (eRATs) for suspected lung or colorectal cancer. We wanted to find out whether GPs were able to integrate these tools into their everyday practice. We were also keen to identify facilitators and barriers to their more widespread use. BACKGROUND: Cancer remains one of UK's biggest health problems, in terms of morbidity and mortality. Comparative European data show that five-year survival figures for many cancers are lower in the United Kingdom than in comparable Euro...
Source: Primary Care - March 3, 2015 Category: Primary Care Authors: Dikomitis L, Green T, Macleod U Tags: Prim Health Care Res Dev Source Type: research

Faecal immunochemical tests for the diagnosis of symptomatic colorectal cancer in primary care: the benefit of more than one sample.
CONCLUSION: Use of a one-sample FIT instead of a three-sample FIT as a diagnostic aid may result in the missing of one tenth of symptomatic CRCs and adenomas with HGD. PMID: 29183266 [PubMed - in process]
Source: Primary Care - December 1, 2017 Category: Primary Care Authors: Högberg C, Söderström L, Lilja M Tags: Scand J Prim Health Care Source Type: research

Indian Health Service Care System and Cancer Stage in American Indians and Alaska Natives.
CONCLUSION: Our results suggest that enrollment in the IHSCS reduced the disparity between AI/ANs and NHWs with respect to late-stage cancer diagnoses. PMID: 29503298 [PubMed - in process]
Source: Journal of Health Care for the Poor and Underserved - March 7, 2018 Category: International Medicine & Public Health Authors: Burnett-Hartman AN, Adams SV, Bansal A, McDougall JA, Cohen SA, Karnopp A, Warren-Mears V, Ramsey SD Tags: J Health Care Poor Underserved Source Type: research

Advanced Stage of Disease and Systemic Inflammation as Factors Associated With Referral of Patients With Colorectal Cancer to a Palliative Care Unit.
CONCLUSION: Advanced disease stage and NLR were associated with referral of patients with CCR to a PCU. PMID: 32031005 [PubMed - as supplied by publisher]
Source: The American Journal of Hospice and Palliative Care - February 6, 2020 Category: Palliative Care Authors: Silva TH, Peres WAF, Rosa KSDC, Schilithz AOC, de Oliveira LC, Murad LB Tags: Am J Hosp Palliat Care Source Type: research

Weekly Overseas Health IT Links –24th September, 2022.
This article makes the case and explains what will be required to make it happen.We hear a lot about “digital health” these days. As data about our health piles up — thanks to sources like electronic health records, personal fitness apps and gadgets, and home genome test kits — weshould understand a lot more than we used to about what ’s wrong with our health and what to do about it. But having a lot of data is not enough. We have to be aware of what we have, understand what it means, and act on that understanding. While the challenges are in some ways more acute in the United States because of its fragmented sys...
Source: Australian Health Information Technology - September 24, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

An Era Of Precision Medicine And Rapid Learning
At a recent White House event, President Obama presented his proposals for a Precision Medicine Initiative. The key elements include a national research system where 1 million or more volunteers can share their (privacy protected) electronic health records, genetics, and other data, and a national cancer initiative. The proposals will be developed in more detail based on meetings led by the National Institutes of Health (NIH) Director Francis Collins. If national health policy adopts these proposals, much about today’s medical care system—including biomedical science, medical education, diagnostics, treatment optio...
Source: Health Affairs Blog - February 20, 2015 Category: Health Management Authors: Lynn Etheredge Tags: All Categories Big Data Chronic Care Innovation Medicaid Medicare Policy Public Health Research Source Type: blogs

Researchers develop non-invasive method to detect tumor-causing mutations in saliva
IMPACT Current methods to screen for lung cancer mutations in plasma or blood are complicated, technique-dependent and not readily available. Electric field-induced release and measurement is a reliable method to detect tumor-causing, lung cancer mutations in saliva that would be non-invasive, cost-effective and rapid. Clinicians could also use this technology to adjust their therapeutic strategies in real-time, improving clinical outcomes. FINDINGS Lung cancer is the leading cause of cancer-related deaths worldwide, accounting for 27 percent of all cancer deaths among both men and women, with about 225,000 new cases diagn...
Source: UCLA Newsroom: Health Sciences - November 14, 2014 Category: Universities & Medical Training Source Type: news

NF κB and Kidney Injury
Conclusion As a critical regulator of inflammation and cell survival, the NFκB pathway is a promising target for diagnosing and treating kidney diseases. For modulation of the NFκB pathway in the clinic, a number of molecules can effectively inhibit NFκB signaling by targeting the receptors, associated adaptors, IKKs, IκBs and transcriptional regulators (144). There is further clinical evidence on small-molecule inhibitors of IKKα and NIK from recent trials on anti-cancer therapies (145). These clinical trials showed that the cancer-selective pharmacodynamic response of DTP3, the co...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Cancer specialist perspectives on implementing an online communication system with primary care providers
Conclusions: Accessing eOncoNote as a separate system was challenging to incorporate into the workflow, and cancer specialists highlighted the need for integration with their EMR. eOncoNote did not affect information sharing with PCPs, as there was limited uptake within primary care.PMID:36696651 | DOI:10.1370/afm.20.s1.3246
Source: Annals of Family Medicine - January 25, 2023 Category: Primary Care Authors: Bojana Petrovic Scott Morgan Amir Afkham Mary Ann O'Brien Jonathan Sussman Margaret Fitch Sharon McGee Clare Liddy Nancy Schneider Eva Grunfeld Source Type: research

Abstract A23: Comprehensive next-generation sequencing-based genomic profiling identifies actionable genomic alterations in diverse pediatric tumor types: The Foundation Medicine (FMI) experience
Conclusions: Comprehensive NGS-based genomic profiling identified alterations in 75% of 193 unselected pediatric cancer clinical cases; and 56% of these patients (N=109) were found to have at least one therapeutically actionable alteration. Widespread deployment of this approach may provide treatment options for pediatric cancer patients. Citation Format: Matthew J. Hawryluk, Kai Wang, Juliann Chmielecki, Siraj M. Ali, Gary Palmer, Lazaro Garcia, Emily White, Roman Yelensky, Philip J. Stephens, Jeffrey S. Ross, Vincent A. Miller. Comprehensive next-generation sequencing-based genomic profiling identifies actionable genomic...
Source: Cancer Research - October 9, 2014 Category: Cancer & Oncology Authors: Hawryluk, M. J., Wang, K., Chmielecki, J., Ali, S. M., Palmer, G., Garcia, L., White, E., Yelensky, R., Stephens, P. J., Ross, J. S., Miller, V. A. Tags: Pediatric Cancer Genomics and Epigenomics Source Type: research