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Nutrition: Vitamins

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Total 439 results found since Jan 2013.

A metabolomic investigation of serum perfluorooctane sulfonate and perfluorooctanoate
CONCLUSIONS: In this large metabolomic study, we observed robust positive associations with PFOS for several molecules. Further investigation of these metabolites may offer insight into PFOS-related biologic effects.PMID:37716341 | DOI:10.1016/j.envint.2023.108198
Source: Cancer Control - September 16, 2023 Category: Cancer & Oncology Authors: Jongeun Rhee Erikka Loftfield Demetrius Albanes Tracy M Layne Rachael Stolzenberg-Solomon Linda M Liao Mary C Playdon Sonja I Berndt Joshua N Sampson Neal D Freedman Steven C Moore Mark P Purdue Source Type: research

Carbohydrate polymers-based surface modified nano delivery systems for enhanced target delivery to colon cancer - A review
Int J Biol Macromol. 2023 Aug 29:126581. doi: 10.1016/j.ijbiomac.2023.126581. Online ahead of print.ABSTRACTCarbohydrate polymers-based surface-modified nano-delivery systems have gained significant attention in recent years for enhancing targeted delivery to colon cancer. These systems leverage carbohydrate polymers' unique properties, such as biocompatibility, biodegradability, and controlled release. These properties make them suitable candidates for drug delivery applications. Nano-delivery systems loaded with bioactive compounds are well-studied for targeted colorectal cancer delivery. However, those drugs' target rea...
Source: International Journal of Biological Macromolecules - August 31, 2023 Category: Biochemistry Authors: Ibrahim Abdel Aziz Ibrahim Abdullah R Alzahrani Ibrahim M Alanazi Naiyer Shahzad Imran Shahid Alaa Hisham Falemban Mohd Fahami Nur Azlina Palanisamy Arulselvan Source Type: research

Delta tocotrienol as a supplement to FOLFOXIRI in first-line treatment of metastatic colorectal cancer. A randomized, double-blind, placebo-controlled phase II study
CONCLUSION: The addition of δ-tocotrienol to FOLFOXIRI did not statistically significant prolong the time to first hospitalization or death compared to FOLFOXIRI plus placebo. Toxicity was manageable and not statistically different. There was a statistically significant difference in dose reductions of oxaliplatin pointing to a possible neuroprotective effect of δ-tocotrienol.PMID:37646150 | DOI:10.1080/0284186X.2023.2249225
Source: Acta Oncologica - August 30, 2023 Category: Cancer & Oncology Authors: Louise Raunkilde Torben Fr østrup Hansen Birgitte Mayland Havelund Caroline Brenner Thomsen S øren Rafael Rafaelsen Jan Lindebjerg Lars Henrik Jensen Source Type: research

Association of DNA methylation of vitamin D metabolic pathway related genes with colorectal cancer risk
CONCLUSIONS: This study indicated that the cumulative methylation levels of significant CpG sites in VDR and CYP24A1 and all CpG sites in CYP2R1 were inversely associated with colorectal cancer risk.PMID:37644572 | PMC:PMC10463505 | DOI:10.1186/s13148-023-01555-0
Source: Clinical Colorectal Cancer - August 29, 2023 Category: Cancer & Oncology Authors: Yi-Fan Wang Lei Li Xue-Qing Deng Yu-Jing Fang Cai-Xia Zhang Source Type: research

Circulating vitamin D concentration and risk of 14 cancers: a bidirectional Mendelian randomization study
CONCLUSIONS: Our findings provide support for a causal relationship between circulating vitamin D concentration and risk of MSC. Additionally, we found a causal relationship between circulating vitamin D concentration and risk of colorectal cancer in reverse-MR analysis. This evidence indicate that vitamin D is of great significance in the prevention and treatment of MSC and the prognosis of colorectal cancer.PMID:37642723 | DOI:10.1007/s00432-023-05322-9
Source: Clinical Colorectal Cancer - August 29, 2023 Category: Cancer & Oncology Authors: Yuxuan Dai Yu Chen Yifu Pu Rui Jiang Source Type: research

Calcium, Vitamin D, and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):47-55. doi: 10.4166/kjg.2023.091.ABSTRACTColorectal cancer has a high incidence and mortality worldwide, with Westernized lifestyles and diet being significant contributing factors. Vitamin D and calcium have been known to reduce the incidence of colorectal cancer by affecting cell differentiation, proliferation, and apoptosis. Despite observational studies which have suggested that a higher serum vitamin D level can lower the risk of colorectal cancer and improve survival rates, no large-scale randomized controlled trials to establish these benefits have been conducted to date. Ca...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Young-Jo Wi Soo-Young Na Source Type: research