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Total 126 results found since Jan 2013.

Applying the COM-B behaviour model to understand factors which impact school immunisation nurses' attitudes towards designing and delivering a HPV educational intervention in post-primary schools for 15-17  year old students in Northern Ireland, UK
CONCLUSION: IMNs feel that they are the most appropriate professionals to design/deliver HPV education for 15-17 year old students. National policy change, based on collaboration between the Public Health Agency and Education Authority, is a key factor in facilitating IMNs to implement this school-based HPV education intervention.PMID:37543445 | DOI:10.1016/j.vaccine.2023.07.066
Source: Vaccine - August 5, 2023 Category: Allergy & Immunology Authors: Terri Flood Marian McLaughlin Ciara M Hughes Iseult M Wilson Source Type: research

The Clinical Utility of Circulating HPV DNA Biomarker in Oropharyngeal, Cervical, Anal, and Skin HPV-Related Cancers: A Review
Pathogens. 2023 Jul 5;12(7):908. doi: 10.3390/pathogens12070908.ABSTRACTHuman papillomavirus (HPV) is recognized as being related to a wide variety of known cancers: cervical, oropharyngeal, anal, vaginal, penile, and skin. For some of these cancers, rigorous algorithms for screening, therapeutical interventions, and follow-up procedures have been established. Vaccination using the nonvalent anti-HPV vaccine, which prevents infection regarding the most frequently involved high-risk HPV types (16, 18, 31, 33, 45, 52, and 58) and low-risk HPV types (6 and 11), has also extensively prevented, controlled, and even eradicated H...
Source: Cancer Control - July 29, 2023 Category: Cancer & Oncology Authors: Ioana Maria Andrioaie Ionut Luchian Costin D ămian Giorgio Nichitean Elena Porumb Andrese Theodor Florin Pantilimonescu Bogdan Trandab ăț Liviu Jany Prisacariu Dana Gabriela Budal ă Daniela Cristina Dimitriu Luminita Smaranda Iancu Ramona Gabriela Urs Source Type: research

Prevalence and distribution of high-risk Human Papillomavirus in Western T ürkiye between 2019 and 2022
This study indicates the need for higher coverage of HPV vaccination in Western Türkiye.PMID:37347660 | DOI:10.1556/030.2023.02066
Source: Acta Microbiologica et Immunologica Hungarica - June 22, 2023 Category: Microbiology Authors: G ülfem Terek Ece Do ğukan Pira G ökçe Lara Bodur Source Type: research

Phase II Trial of MEDI0457 and Durvalumab for Patients With Recurrent/Metastatic Human Papillomavirus-Associated Cancers
CONCLUSIONS: The combination of MEDI0457 and durvalumab demonstrated acceptable safety and tolerability in patients with advanced HPV-16/18 cancers. The low ORR among patients with cervical cancer led to study discontinuation despite a clinically meaningful disease control rate.PMID:37104874 | DOI:10.1093/oncolo/oyad085
Source: Cancer Control - April 27, 2023 Category: Cancer & Oncology Authors: Van K Morris Amir Jazaeri Shannon N Westin Curtis Pettaway Solly George Ryan W Huey Michaela Grinsfelder Aaron Shafer Benny Johnson David Vining Ming Guo Bryan Fellman Michael Frumovitz Source Type: research

Highlights into historical and current immune interventions for cancer
Int Immunopharmacol. 2023 Feb 27;117:109882. doi: 10.1016/j.intimp.2023.109882. Online ahead of print.ABSTRACTImmunotherapy is an additional pillar when combined with traditional standards of care such as chemotherapy, radiotherapy, and surgery for cancer patients. It has revolutionized cancer treatment and rejuvenated the field of tumor immunology. Several types of immunotherapies, including adoptive cellular therapy (ACT) and checkpoint inhibitors (CPIs), can induce durable clinical responses. However, their efficacies vary, and only subsets of cancer patients benefit from their use. In this review, we address three goal...
Source: International Immunopharmacology - February 27, 2023 Category: Allergy & Immunology Authors: Kathryn Cole Zaid Al-Kadhimi James E Talmadge Source Type: research

The relationship of human papillomavirus positivity with tumor characteristics in an Irish penile cancer population
CONCLUSIONS: Our data is representative of the Irish landscape in penile cancer over the last five years. Using p16INK4a staining, we demonstrate a high rate of HPV prevalence in penile cancer cases in our patient cohort, which is associated with prognostically worse tumor subtypes. This would suggest that HPV vaccination of adolescent boys is a useful public health intervention in preventing penile cancer in the Irish male population.PMID:36656691 | DOI:10.5489/cuaj.7821
Source: Canadian Urological Association Journal - January 19, 2023 Category: Urology & Nephrology Authors: Eva Browne Megan Power Foley John O'Kelly Aisling Nic An R íogh Nigam Shah Christine Shilling John P Keane Padraig Daly Ivor M Cullen Source Type: research