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Total 29465 results found since Jan 2013.

Implementation of a pharmaceutical care programme for patients receiving new molecular ‐targeted agents in a clinical trial unit
A pharmaceutical care programme was implemented at our hospital in early 2013. The main objectives were to analyse and describe the pharmaceutical interventions made, to calculate adherence, interventions and to evaluate patient satisfaction with the care programme. We performed a single‐centre descriptive and prospective intervention in cancer patients who received oral chemotherapy as part of a clinical trial in 2013. Eighty‐three patients were included. Median age was 58 years (range, 31–80) and 42 patients (50.6%) were men. We recorded 23 interventions, 13 of which were associated with drug interactions. The mea...
Source: European Journal of Cancer Care - January 20, 2016 Category: Cancer & Oncology Authors: G. Riu, L. Gaba, I. Victoria, G. Molas, F. Pazo, B. G ómez, N. Creus, L. Vidal Tags: Original Article Source Type: research

An investigation into the nutritional status of patients receiving an Enhanced Recovery After Surgery (ERAS) protocol versus standard care following Oesophagectomy
ConclusionA standardised post-operative nutrition protocol, within an ERAS framework, results in earlier transition to oral intake; however, malnutrition remains prevalent post surgery. Further large-scale studies are warranted to examine individualised decision-making regarding nutrition support within an ERAS protocol.
Source: Supportive Care in Cancer - April 26, 2018 Category: Cancer & Oncology Source Type: research

Perception of need for nutritional support in advanced cancer patients with cachexia: a survey in palliative care settings
ConclusionsPatients with cancer cachexia expressed a greater need for nutritional support. They wished to receive nutritional support from medical staff when they become unable to take sufficient nourishment orally and the negative impact of cachexia becomes apparent. Most patients wished to receive parenteral nutrition and hydration.
Source: Supportive Care in Cancer - June 25, 2018 Category: Cancer & Oncology Source Type: research

Olanzapine in the treatment of refractory nausea and vomiting in palliative care settings
We report a case of gallbladder carcinoma who presented to us with intractable vomiting which was not relieved with a combination of traditional antiemetics but showed marked improvement with olanzapine.
Source: Indian Journal of Palliative Care - July 16, 2018 Category: Palliative Care Authors: Nishkarsh Gupta Sidharth Puri Vinod Kumar Rakesh Garg Sachidanand Jee Bharati Seema Mishra Sushma Bhatnagar Source Type: research

A case report of the efficacy and usefulness of asenapine in the treatment of a cancer patient with delirium and aphagia.
Abstract OBJECTIVE: Controlling hyperactive and mixed delirium is extremely important for the continuation of cancer treatment in palliative care. In general, oral antipsychotics are the first-line drug therapy for delirium; however, oral administration is problematic in patients presenting dysphagia. In this case report, we describe an end-stage cancer patient with aphagia who developed delirium and responded to sublingual antipsychotic asenapine for treating delirium. We also discuss the effectiveness of asenapine in hyperactive delirium as well as its usefulness for treating delirium in palliative care. ME...
Source: Palliative and Supportive Care - December 26, 2018 Category: Palliative Care Authors: Osawa K, Ukai S, Kuriyama T Tags: Palliat Support Care Source Type: research

Patient Counseling Guidelines for the Use of Cannabis for the Treatment of Chemotherapy-Induced Nausea/Vomiting and Chronic Pain.
Authors: Makary P, Parmar JR, Mims N, Khanfar NM, Freeman RA Abstract The use of cannabis medications has grown in recent years for the symptomatic relief of chemotherapy-induced nausea/vomiting (CINV) and chronic pain (cancer-related and non-cancer-related). As states legalize the use of cannabis, it is important for pharmacists and other health care professionals to be aware of how to counsel patients receiving prescriptions for cannabis medications. The aim of this study was to develop patient counseling guidelines for the use of cannabis products in treatment of CINV and chronic pain. A literature search was pe...
Source: Journal of Pain and Palliative Care Pharmacotherapy - May 10, 2019 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Continuous measurement of combined oximetry and transcutaneous carbon dioxide in patients with opioid-treated chronic pain in a palliative care setting
Conclusion: It is feasible to continuously monitor ventilation noninvasively using combined SpO2 and TcCO2 to detect hypoventilation in the palliative care setting. Patients with advanced cancer administered opioids in palliative care are at risk of manifesting hypercapnia and hypoxemia.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Chhajed, P. N., Leuppi-Taegtmeyer, A., Shwarz-Zindel, M. S., Dieterle, T., Zylicz, B., Leuppi, J. D. Tags: Rehabilitation and chronic care Source Type: research

Herb medicine for relieving radiation induced oral mucositis: A systematic review and meta-analysis protocol
Conclusion: This study will provide evidence to help determine whether Chinese herbal medicine is effective and safe for use in the prevention and/or treatment of radiotherapy induced OM. Ethics and dissemination: No additional formal ethical recognition or informed consent is required since no primary data collection is involved. The study result will be published in peer-reviewed journals or at related conferences. PROSPERO registration number: PROSPERO CRD42019141900.
Source: Medicine - December 1, 2019 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

A prospective study on oral adverse effects in head and neck cancer patients submitted to a preventive oral care protocol
ConclusionsThe findings of this study suggest a positive effect of an oral preventive care program for head and neck cancer patients submitted to RT. The PBMT associated with a rigorous POCP resulted in satisfactory control of oral adverse effects, reduction of quality of life impacts, and interruption of RT regimen due to severe OM.
Source: Supportive Care in Cancer - January 2, 2020 Category: Cancer & Oncology Source Type: research

Unfolding role of erector spinae plane block for the management of chronic cancer pain in the palliative care unit
Prashant Sirohiya, Pratishtha Yadav, Sachidanand Jee Bharati, Bhatnagar SushmaIndian Journal of Palliative Care 2020 26(1):142-144 Pain adversely affects the quality of life in cancer patients. Although conventional oral analgesics and co-analgesics manage 80%–90% of pain, interventional pain management techniques may be useful in the management of cancer pain refractory to opioid analgesia or in patients unable to tolerate systemic opioids. Herein, we report three cases depicting the successful role of erector spinae plane block in our palliative care unit for the management of differen...
Source: Indian Journal of Palliative Care - January 27, 2020 Category: Palliative Care Authors: Prashant Sirohiya Pratishtha Yadav Sachidanand Jee Bharati Bhatnagar Sushma Source Type: research

A Multi-Centered Case Series Highlighting the Clinical Use and Dosing of Lidocaine and Mexiletine for Refractory Cancer Pain.
Authors: Atayee RS, Naidu D, Geiger-Hayes J, Saphire ML, Hausdorff J, Edmonds KP Abstract Lidocaine infusion for pain control has been used for years. While some centers transition from continuous infusion lidocaine to oral mexiletine, there are no published studies to guide this conversion in pain and palliative care settings. This is a retrospective case series of 10 cancer patients across four institutions, with attention to dosing of both agents, and subsequent decrease in morphine-equivalent daily dosing (MEDD). The mean age was 55 years (range 34-78). The mean bolus dose of lidocaine was 1.6 mg/kg, infuse...
Source: Journal of Pain and Palliative Care Pharmacotherapy - February 25, 2020 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Traditional Chinese medicine for oral squamous cell carcinoma: A Bayesian network meta-analysis protocol
Conclusions: The findings will provide reference for evaluating the efficacy and safety of different traditional Chinese medicine for OSCC, and provide a helpful evidence for clinicians to formulate the best adjuvant treatment strategy for OSCC patients. Trial registration number: INPLASY202090082.
Source: Medicine - October 23, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Cost of home vs clinic administration of paclitaxel in metastatic breast cancer.
CONCLUSIONS: Home administration of oral paclitaxel and encequidar was associated with lower administration costs compared with once-every-3-weeks IV paclitaxel (175 mg/m2) and protein-bound paclitaxel, resulting in potential cost savings for payers. PMID: 33395244 [PubMed - as supplied by publisher]
Source: The American Journal of Managed Care - December 24, 2020 Category: Health Management Authors: Sharma D, Wojtynek J, Fox KM, Cooper C, Dokubo I Tags: Am J Manag Care Source Type: research

Body mass index and self-care behaviors related to oral health –related quality of life in patients with oral squamous cell carcinoma within three months posttreatment
ConclusionsThe severity of adverse effects after self-care behaviors and using feeding tubes during treatment strongly influenced overall OHRQoL and seven specific dimensions of OHRQoL.
Source: Supportive Care in Cancer - February 19, 2021 Category: Cancer & Oncology Source Type: research

The impact of the COVID-19 outbreak on supportive care for oral mucositis: current concepts and practice
AbstractThe outbreak of coronavirus disease 2019 (COVID-19) markedly affected the way healthcare professionals approach patients with cancer worldwide, not only in terms of therapeutic decision-making but also in terms of supportive care. With the rapid appearance of signs and symptoms and the need of close re-assessment, standard management of oral mucositis has been challenged by physical distancing and limited resources due to the global crisis. Building on the clinical experience developed during the acute phase by members of the Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/Intern...
Source: Supportive Care in Cancer - March 20, 2021 Category: Cancer & Oncology Source Type: research