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Allergic Contact Dermatitis To Fentanyl TTS With Good Tolerance To Systemic Fentanyl.
CONCLUSION: We present the case of allergic contact dermatitis (ACD) due to hypersensitivity to fentanyl with good tolerance to buprenorphine. Positive PT in this patient suggests a type IV hypersensitivity mechanism. Allergic reactions to opioids are frequently immediate, but delayed reactions could appear, especially when the drug is administered topically. PMID: 31131754 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - May 29, 2019 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Validation of a 16th Century Traditional Chinese Medicine Use of Ginkgo biloba as a Topical Antimicrobial
This study aimed to examine the traditional use of Ginkgo seeds as topical treatment for skin disorders for potential antibacterial efficacy. This is the first study to test and compare the antibacterial activity of various Ginkgo seed extracts on skin pathogens. In this work, we confirmed the ethnomedicinal importance of seeds in the treatment of skin diseases. As reported in the Compendium of Materia Medica Ben Cao Gang Mu, only the seeds were used for medicinal uses, especially as a topical treatment for skin infections. Moreover, our study validates the antimicrobial activity of the seed (i.e., seed coats and immature...
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

BET Bromodomain Inhibitor iBET151 Impedes Human ILC2 Activation and Prevents Experimental Allergic Lung Inflammation
This study was supported by grants from GSK and the UK Medical Research Council (U105178805). Conflict of Interest Statement AM has grant funding from GSK and AstraZeneca/MedImmune. MB, DJ, AP, DT, and AvO are employees of GSK. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments We are grateful to the Ares staff, genotyping facility, and flow cytometry core for their technical assistance. We thank Jen Walker for advice on the manuscript. Supplementary Material The Supplem...
Source: Frontiers in Immunology - April 8, 2019 Category: Allergy & Immunology Source Type: research

Spring health cheat sheet
As the spring weather approaches, many common winter infections recede. However, warmer temperatures can introduce a new set of health challenges. As trees and flowers bloom and grass grows, susceptible children will start to display symptoms of seasonal allergies, triggering flares of asthma and eczema. And, As children spend more time outdoors, parents also need to watch for exposure to ticks, poison ivy and excess sun. Here are a few tips to keeping your child healthy this spring. Seasonal allergies: What can you do? During allergy season: have your child bathe after spending time outdoors to remove allergens fro...
Source: Thrive, Children's Hospital Boston - April 7, 2017 Category: Pediatrics Authors: Carolyn Sax Tags: Health & Wellness Parenting allergies asthma Carolyn Sax conjunctivitis lyme disease sunburn Source Type: news