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Cancer: Liver Cancer
Infectious Disease: HIV AIDS
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Total 40 results found since Jan 2013.
A spliceosome-associated gene signature aids in predicting prognosis and tumor microenvironment of hepatocellular carcinoma
In conclusion, a spliceosome-related six-gene signature exhibited good performance for predicting the OS of patients with HCC, which may aid in clinical decision-making for individual treatment.PMID:37301543 | DOI:10.18632/aging.204765
Source: Aging - June 10, 2023 Category: Biomedical Science Authors: Huaxiang Wang Ruling Wang Jian Fang Source Type: research
NIO-1, a novel inhibitor of OCT1, enhances the antitumor action of radiofrequency ablation against hepatocellular carcinoma
CONCLUSION: This study demonstrated the clinical importance of OCT1 expression in HCC for the first time. Our findings also revealed that NIO-1 aids RFA therapy by targeting OCT1.PMID:37246325 | DOI:10.2174/1566524023666230526154739
Source: Molecular Medicine - May 29, 2023 Category: Molecular Biology Authors: Hua Yang Yang Yang Xiaozheng Zou Qian Zhang Xiaoli Li Chunyu Zhang Yanan Wang LiLi Ren Source Type: research
Ganetespib (STA-9090) augments sorafenib efficacy via necroptosis induction in hepatocellular carcinoma: Implications from preclinical data for a novel therapeutic approach
Biomed Pharmacother. 2023 May 20;164:114918. doi: 10.1016/j.biopha.2023.114918. Online ahead of print.ABSTRACTSorafenib, a multikinase inhibitor, is a first-line treatment for advanced hepatocellular carcinoma, but its long-term effectiveness is limited by the emergence of resistance mechanisms. One such mechanism is the reduction of microvessel density and intratumoral hypoxia caused by prolonged sorafenib treatment. Our research has demonstrated that HSP90 plays a critical role in conferring resistance to sorafenib in HepG2 cells under hypoxic conditions and N-Nitrosodiethylamine-exposed mice as well. This occurs through...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 22, 2023 Category: Drugs & Pharmacology Authors: Sameh Saber Alexandru Madalin Hasan Osama A Mohammed Lobna A Saleh Abdullah A Hashish Mohannad Mohammad S Alamri Ahmed Y Al-Ameer Jaber Alfaifi Ahmed Senbel Adel Mohamed Aboregela Tarig Babikir Algak Khalid Mustafa Ahmed Abdel-Reheim Simona Cavalu Source Type: research
Survival outcomes in Veterans with hepatocellular carcinoma, with and without HIV infection
CONCLUSION: HIV status was not associated with worse survival among HCC patients, in a single-payer, equal access health care system. These results suggest that HIV infection alone should not exclude PLWH from receiving standard therapy.PMID:37070557 | DOI:10.1097/QAD.0000000000003568
Source: Cancer Control - April 18, 2023 Category: Cancer & Oncology Authors: Yvonne H Sada Wilson L da Costa Jennifer R Kramer Elizabeth Y Chiao Efthalia Zafeiropoulou Yongquan Dong Liang Chen Bich N Dang Source Type: research
Viral hepatitis in persons living with HIV in the post-COVID era
AIDS Rev. 2023;25(1):1-13. doi: 10.24875/AIDSRev.M23000061.ABSTRACTCoinfection with hepatitis viruses A to E is frequent in persons living with HIV (PLWH) and causes significant morbidity and mortality. Oro-fecal transmissible hepatitis A and E mostly produce acute self-limited episodes in poor income regions and in non-vaccinated travelers. In high-income countries, outbreaks of hepatitis A occur in men having sex with men (MSM) and chronic hepatitis E is occasionally reported among PLWH with severe immunodeficiency. Chronic hepatitis B, C, and D are frequent in PLWH in highly endemic regions and globally in persons who i...
Source: AIDS Reviews - March 23, 2023 Category: Infectious Diseases Authors: Vicente Soriano V íctor Moreno-Torres Carmen de Mendoza Octavio Corral Pablo Barreiro Source Type: research
